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Syllabus(As per ER 1991)Antiseptics and Disinfectants-Proflavine*, Benzalkonium chloride, Cetrimide, Phenol, chloroxylenol, Formaldehyde solution, Hexachlophene, Nitrofurantoin. Sulphonamides- Sulphadiazine, Sulphaguanidine, Phthalylsulphathaizole, Succinylsulphathiazole, Sulphadimethoxine, Sulphamethoxypyridazine, Co-trimoxazole, sulfacetamide* Antileprotic Drugs-Clofazimine, Thiambutosine, Dapsone*, solapsone, Anti-tubercular Drugs- Isoniazid*, PAS*, Streptomycin, Rifampicin, Ethambutol*, Thiacetazone, Ethionamide, cycloserine, pyrazinamide*. Antimoebic and Anthelmintic Drugs- Emetine, Metronidazole, Halogenated hydroxyquinolines, Diloxanide furoate, Paromomycin, Piperazine*, Mebendazole, D.E.C.* Antibiotics- Benzyl penicillin*, Phenoxy methyl penicillin*, Benzathine penicillin, Ampicillin*, Cloxacillin, Carbencicillin, Gentamicin, Neomycin, Erythromycin, Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofulvin, Chloramphenicol. Antifungal agents- Udecylenic acid, Tolnaftate, Nystatin, Amphotericin, Hamycin. Antimalarial Drugs-Chloroquine*, Amodiaquine, Primaquine, Proguanil, Pyrimethamine*, Quinine, Trimethoprim. Tranquilizers-Chlorpromazine*, Prochlorperazine, Trifluoperazine, Thiothixene, Haloperiodol*, Triperiodol, Oxypertine, Chlordizepoxide, Diazepam*, Lorazepam, Meprobamate. Hypnotics- Phenobarbitone*, Butobarbitone, Cylobarbitone, Nitrazepam, Glutethimide*, Methyprylon, Paraldehyde, Triclofosodium. General Anaesthetics-Halothane*, Cyclopropane*, Diethyl ether*, Methohexital sodium, Thiopecal sodium, Trichloroethylene . Antidepressant Drugs- Amitriptyline, Nortryptyline, Imperamine*, Phepelzine, Tranylcypromine. Analeptics- Theophylline, Caffeine*, Coramine*, Dextro-amphetamine.Adrenergic drugs- Adrenaline*, Noradrenaline, Isoprenaline*, Phenylephrine, Salbutamol, Terbutaline, Ephedrne*, Pseudoephedrine. Adrenergic antagonist- Tolazoline, Propranolol*, Practolol. Cholinergic Drugs- Neostigmine*, Pyridostigmine, Pralidoxime, Pilocarpine, Physostigmine*. Cholinergic Antagonists- Atropine*, Hyoscine, Homatropine, Propantheline*, Benztropine, Tropicamide, Biperiden*. Diuretic Drugs- Furosemide*, Chlorothiazide, Hydrochlorothiazidc*, Benzthiazide, Urea*, Mannitol*, Ethacrynic Acid. Cardiovascular Drugs- Ethylnitrite*, Glyceryl trinitrate, Alpha methyldopa, Guanethidine, Clofibrate, Quinidine. Hypoglycaemic Agents- Insulin, Chlorpropamide*, Tolbutamide, Glibenclamide, Phenformin*, Metformin. Coagulants and Anti coagulants- Heparin, Thrombin, Menadione*, Bisphydroxy-coumarin, Warfarin sodium. Local Anaesthetics- Lignocaine*, Procaine*, Benzocaine, Histamine and anti-Histaminic Agents- Histamine, Diphenhydramine*, Promethazine, Cyproheptadine, Mepyramine*, Pheniramine, Chlorpheniramine*, Analgesics and Anti-pyretics- Morphine, Pethidine, Codeine, Mathadone, Aspirin*, Paracetamol, Analgin, Dextropropoxphene, Pentazocine. Non-steriodal anti-inflammatory agents- Indomethacin*, Phenylbutazone*, Oxyphenbutazone, Ibuprofen. Thyroxine and Antithyroids- Thyroxine*, Methimazole, Methyl thiouracil, Propylthiouracil. Diagnostic Agents- Lopanoic Acid, Propyliodone, Sulfobromopthalein-sodium, Indigotindisulfonate, Indigo Carmine, Evans blue, Congo Red, Fluorescein sodium. Anticonvulsants, cardiac glycosides, Antiarrhythmic, Antihypertensives&Vitamins.Steroidal Drugs- Betamethasone, Cortisone, Hydrocortisone, Prednisolone, Progesterone, Testosterone, Oestradiol, Nandrolone. Anti-Neoplastic Drugs- Actinomycin, Azathioprie, Busulphan, Chloramubucil, Cisplatin, Cyclophosphamide, Daunorubicin Hydrochoride, Fluorouracil, Mercaptopurine, Methotrexate, Mytomycin.
Introduction. Centrak Nervous System Stimulants. Antidepressants and Antinxienty Agent (Anxiolytic). Antipsychotic Agents and Hallucinogens. General Anaestetics. Hypnotics and Sedatives. Skeletal Muscle Relaxants. Tranquilizing Agents. Anticonvulsant Drugs. Analgesics (Narcotcs). Anpyertic Analgesics. Nonsteroidal Anti- Inflammatory Agents. Adrenergic Agents. Adrenergic Blocking Agents. Cardiovascular Agents. Histamines & Antihistaminic Agents. antitussives & Expectorants. Coagulants and Anticoagulants
Pharmaceutical Organic Chemistry has been written keeping in mind the severe need for a comprehensive text to meet the curriculum needs of the undergraduate pharmacy students. It not only provides all the curriculum topics to the students but also contains all the vital reactions/mechanisms that the students look for in an organic chemistry book. - Entire subject matter has been written in a systematic and lucid style in simple language. - All the basic concepts and fundamentals of organic chemistry have been explained with well-chosen examples. - For better understanding of the subject matter, important points have been highlighted in the form of the textboxes titled as Remember, Learning Plus and Noteworthy Points, wherever required. - Summary of the topics in the form of Memory Focus has been given at relevant places to help the students to revise the subject matter quickly. - Stepwise mechanism of the reactions as per the syllabus has been illustrated, laying emphasis on the reactive intermediates involved. - At the end of each chapter, Revision Questions including descriptive questions and short answer questions have been given for the students to practice. Multiple Choice Questions with answers have been included at the end of each chapter.
The second edition of the book continues to offer a range of pedagogical features maintaining the balanced approach of the text. The attempts have been made to further strengthen the conceptual understanding by introducing more ideas and a number of solved problems. Comprehensive in approach, this text presents a rigorous treatment of organic chemistry to enable undergraduate students to learn the subject in a clear, direct, easily understandable and logical manner. Presented in a new and exciting way, the goal of this book is to make the study of organic chemistry as stimulating, interesting, and relevant as possible. Beginning with the structures and properties of molecules, IUPAC nomenclature, stereochemistry, and mechanisms of organic reactions, proceeding next to detailed treatment of chemistry of hydrocarbons and functional groups, then to organometallic compounds and oxidation–reduction reactions, and ending with a study of selected topics (such as heterocyclic compounds, carbohydrates, amino acids, peptides and proteins, drugs and pesticides, dyes, synthetic polymers and spectroscopy), the book narrates a cohesive story about organic chemistry. Transitions between topics are smooth, explanations are lucid, and tie-ins to earlier material are frequent to maintain continuity. The book contains over 500 solved problems from simple to really challenging ones with suitable explanations. In addition, over 275 examples and solved problems on IUPAC nomenclature, with varying levels of difficulty, are included. About Some Key Features of the Book • EXPLORE MORE: Four sets of solved problems provide in-depth knowledge and enhanced understanding of some important aspects of organic chemistry. • MINI ESSAYS: Three small essays present interesting write-ups to provide students with introductory knowledge of chemistry of natural products such as lipids, terpenes, alkaloids, steroids along with nucleic acids and enzymes. • NOTABILIA: Twenty-two ‘notabilia boxes’ interspersed throughout the text highlight the key aspects of related topics, varying from concepts of chemistry to the chemistry related to day-to-day life. • STRUCTURES AND MECHANISMS NOT IN ORDER: Cites examples of common errors made by students while drawing structural formulae and displaying arrows in reaction mechanisms and helps them to improve on language of organic chemistry by teaching appropriate drawings and their significance. • GLOSSARY: Includes ‘Name reactions’, ‘Reagents’, and some important terms for quick revision by students. Clearly written and logically organized, the authors have endeavoured to make this complex and important branch of science as easy as possible for students to learn from and for teachers to teach from.
Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.
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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization