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This biographical collection highlights individuals who made outstanding achievements in the arenas of pharmaceuticals and biotechnology. Pharmaceutical Achievers presents chronologically the major directions of pharmaceutical research and, in their historical context, the breakthroughs in treating various diseases. It concludes with a look at tomorrow's medicines. This work is particularly useful in the classroom, where its accounts of challenges and triumphs may inspire students to consider careers that support pharmaceutical research and development.
This book was designed to help teachers supplement science curricula with human stories of discovery in the chemical sciences. Chemical Achievers presents the lives and work of two types of achievers. First are the historical greats, those chemical scientists most often referred to in introductory courses. Second are those scientists who made contributions in areas of the chemical sciences that are of special relevance to modern life and the career choices students will make. The human faces summarized in this book range from Robert Boyle to Glenn Seaborg and Stephanie Kwolek. In this lively and comprehensive collection of photographs and biographies, Bowden illuminates how much the chemical sciences owe to the individual achiever. Over 150 images can be easily reproduced as overhead transparencies or other visual teaching aids.
The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.
Every business faces the existential threat of competitors producing cheaper copies. Even patent filings, market dominance and financial resources can't shield them from copycats. So what can we do -- and, what can we learn from companies that have endured and even prospered for centuries despite copycat competition? In a book of narrative history and practical strategy, IMD professor of management and innovation Howard Yu shows that succeeding in today's marketplace is no longer just a matter of mastering copycat tactics, companies also need to leap across knowledge disciplines, and to reimagine how a product is made or a service is delivered. This proven tactic can protect a company from being overtaken by new (and often foreign) copycat competitors. Using riveting case studies of successful leaps and tragic falls, Yu illustrates five principles to success that span a wide range of industries, countries, and eras. Learn about how P&G in the 19th century made the leap from handcrafted soaps and candles to mass production of its signature brand Ivory, leaped into the new fields of consumer psychology and advertising, then leaped again, at the risk of cannibalizing its core product, into synthetic detergents and won with Tide in 1946. Learn about how Novartis and other pharma pioneers stayed ahead by making leaps from chemistry to microbiology to genomics in drug discovery; and how forward-thinking companies, including China's largest social media app -- WeChat, Tokyo-based Internet service provider Recruit Holdings, and Illinois-headquartered John Deere are leaping ahead by leveraging the emergence of ubiquitous connectivity, the inexorable rise of intelligent machines, and the rising importance of managerial creativity. Outlasting competition is difficult; doing so over decades or a century is nearly impossible -- unless one leaps. Ultimately, Leap is a manifesto for how pioneering companies can endure and prosper in a world of constant change and inevitable copycats.
Named a Best Book of the Year by The New Yorker and The Boston Globe An authoritative, illuminating, and deeply humane history of addiction—a phenomenon that remains baffling and deeply misunderstood despite having touched countless lives—by an addiction psychiatrist striving to understand his own family and himself “Carl Erik Fisher’s The Urge is the best-written and most incisive book I’ve read on the history of addiction. In the midst of an overdose crisis that grows worse by the hour and has vexed America for centuries, Fisher has given us the best prescription of all: understanding. He seamlessly blends a gripping historical narrative with memoir that doesn’t self-aggrandize; the result is a full-throated argument against blaming people with substance use disorder. The Urge is a propulsive tour de force that is as healing as it is enjoyable to read.” —Beth Macy, author of Dopesick Even after a decades-long opioid overdose crisis, intense controversy still rages over the fundamental nature of addiction and the best way to treat it. With uncommon empathy and erudition, Carl Erik Fisher draws on his own experience as a clinician, researcher, and alcoholic in recovery as he traces the history of a phenomenon that, centuries on, we hardly appear closer to understanding—let alone addressing effectively. As a psychiatrist-in-training fresh from medical school, Fisher was soon face-to-face with his own addiction crisis, one that nearly cost him everything. Desperate to make sense of the condition that had plagued his family for generations, he turned to the history of addiction, learning that the current quagmire is only the latest iteration of a centuries-old story: humans have struggled to define, treat, and control addictive behavior for most of recorded history, including well before the advent of modern science and medicine. A rich, sweeping account that probes not only medicine and science but also literature, religion, philosophy, and public policy, The Urge illuminates the extent to which the story of addiction has persistently reflected broader questions of what it means to be human and care for one another. Fisher introduces us to the people who have endeavored to address this complex condition through the ages: physicians and politicians, activists and artists, researchers and writers, and of course the legions of people who have struggled with their own addictions. He also examines the treatments and strategies that have produced hope and relief for many people with addiction, himself included. Only by reckoning with our history of addiction, he argues—our successes and our failures—can we light the way forward for those whose lives remain threatened by its hold. The Urge is at once an eye-opening history of ideas, a riveting personal story of addiction and recovery, and a clinician’s urgent call for a more expansive, nuanced, and compassionate view of one of society’s most intractable challenges.
A fast-paced, medical-historical mystery, filled with twists and turns.-Chicago Tribune
Profiles more than 200 American men and women who made significant contributions to science during the twentieth century.
The West's history is one of extraordinary success; no other region, empire, culture, or civilization has left so powerful a mark upon the world. The Rise of Western Power charts the West's achievements-representative government, the free enterprise system, modern science, and the rule of law-as well as its misdeeds-two frighteningly destructive World Wars, the Holocaust, imperialistic domination, and the Atlantic slave trade. Adopting a global perspective, Jonathan Daly explores the contributions of other cultures and civilizations to the West's emergence. Historical, geographical, and cultural factors all unfold in the narrative. Adopting a thematic structure, the book traces the rise of Western power through a series of revolutions-social, political, technological, military, commercial, and industrial, among others. The result is a clear and engaging introduction to the history of Western civilization.
Since ancient times the search for cures for the great scourges that have afflicted humankind has been an ongoing quest, but it is only within the last 200 years that major breakthroughs have occurred and the development of modern medicine has accelerated. The stories behind these miraculous cures are those of intense rivalries and jealousies, bitter public humiliation, unswerving dedication, subterfuge, and great personal struggles. Often these medical advances have truly changed the world. When Edward Jenner developed the concept of vaccination, and with it the cure for smallpox, he found a way to defeat a disease that had affected half a billion people - more than all those affected by wars and other epidemics combined. And while the Black Death still lingers in pockets around the world, it no longer threatens to destroy entire civilisations as it once did. Smallpox, Syphilis and Salvation uncovers the compelling stories of the men and women, innovations and accidents that have led to diseases from polio to syphilis, diphtheria to diabetes, tetanus to leukaemia no longer being the death sentences they once were. It also sounds a note of warning - for some of these diseases are fighting back. It is estimated that tuberculosis now claims one life every fifteen seconds, while new 'superbugs' are resistant to penicillin and other antibiotics. Diseases may once again threaten to crush the world's population, either in the form of biological warfare or simply because they want to survive as much as we do...