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One of the most striking features of the twentieth century has been the rapid growth of the pharmaceutical industry and the large increases in the use and consumption of its products. This trend began in the first half of the century, but accelerated most sharply after the Second World War, when the creation of national systems of healthcare created mass markets for drugs. The industry then assumed a major economic, social and political significance, and became one of the most highly regulated sectors of the economy, attracting the attention of industry analysts as well as academics. This volume brings together a collection of papers exploring and reflecting upon some of the significant strands in the current studies of pharmaceuticals in the twentieth century. They touch upon many of the issues that are matters of concern and debate today, and their international and multidisciplinary approaches enrich our understanding of an object, of an industry, and of a process that are at the heart of our highly medicalized contemporary societies.
Examines the impact and importance of the health education film in Europe and North America in the first half of the twentieth century.
A key volume on a central aspect of the history of medicine and its social relations, The History of Healthcare in Public and Private examines how the modernisation of healthcare resulted in a wide variety of changing social arrangements in both public and private spheres. This book considers a comprehensive range of topics ranging from children's health, mental disorders and the influence of pharmaceutical companies to the systems of twentieth century healthcare in Britain, Eastern Europe and South Africa. Covering a broad chronological, thematic and global scope, chapters discuss key themes such as how changing economies have influenced configurations of healthcare, how access has varied according to lifecycle, ethnicity and wealth, and how definitions of public and private have shifted over time. Containing illustrations and a general introduction that outlines the key themes discussed in the volume, The History of Healthcare in Public and Private is essential reading for any student interested in the history of medicine.
The essays in this collection examine how human heredity was understood between the end of the First World War and the early 1970s. The contributors explore the interaction of science, medicine and society in determining how heredity was viewed across the world during the politically turbulent years of the twentieth century.
The tension between innovation and financialisation is central to the business corporation. Innovation entails a 'retain-and-reinvest' allocation regime that can form a foundation for stable and equitable economic growth. Driven by shareholder-value ideology, financialisation entails a shift to 'downsize-and-distribute'. This Element investigates this tension in global pharmaceuticals, focusing on the two leading UK companies AstraZeneca and GlaxoSmithKline. In the 2000s both adopted US-style governance, including stock buybacks and stock-based executive pay. Over the past decade, however, first AstraZeneca and then GlaxoSmithKline transitioned to innovation. Critical was the cessation of buybacks to refocus capabilities on investing in an innovative drugs pipeline. Enabling this shift were UK corporate-governance institutions that mitigated US-style shareholder-value maximisation. Reinventing capitalism for the sake of stable and equitable economic growth means eliminating value destruction caused by financialisation and supporting value creation through collective and cumulative innovation. This title is also available as Open Access on Cambridge Core.
In its decades-long effort to assure the safety, efficacy, and security of medicines and other products, the Food and Drug Administration has struggled with issues of funding, proper associations with industry, and the balance between consumer choice and consumer protection. Today, these challenges are compounded by the pressures of globalization, the introduction of novel technologies, and fast-evolving threats to public health. With essays by leading scholars and government and private-industry experts, FDA in the Twenty-First Century addresses perennial and new problems and the improvements the agency can make to better serve the public good. The collection features essays on effective regulation in an era of globalization, consumer empowerment, and comparative effectiveness, as well as questions of data transparency, conflicts of interest, industry responsibility, and innovation policy, all with an emphasis on pharmaceuticals. The book also intervenes in the debate over off-label drug marketing and the proper role of the FDA before and after a drug goes on the market. Dealing honestly and thoroughly with the FDA's successes and failures, these essays rethink the structure, function, and future of the agency and the effect policy innovations may have on regulatory institutions abroad.
This collection takes the perspective that the historiography of science, technology, and medicine needs a broader approach toward regulation. The authors explore the distinct social worlds involved in regulation, the forms of evidence and expertise mobilized, and means of intervention chosen to tame drugs in factories, consulting rooms and courts.
This book reconstructs the early circulation of penicillin in Spain, a country exhausted by civil war (1936–1939), and oppressed by Franco’s dictatorship. Embedded in the post-war recovery, penicillin’s voyages through time and across geographies – professional, political and social – were both material and symbolic. This powerful antimicrobial captivated the imagination of the general public, medical practice, science and industry, creating high expectations among patients, who at times experienced little or no effect. Penicillin’s lack of efficacy against some microbes fueled the search for new wonder drugs and sustained a decades-long research agenda built on the post-war concept of development through scientific and technological achievements. This historical reconstruction of the social life of penicillin between the 1940s and 1980s – through the dictatorship to democratic transition – explores political, public, medical, experimental and gender issues, and the rise of antibiotic resistance.
Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.
This fascinating study of early cinema in the Netherlands Indies explores the influences of new media technology on colonial society. The Komedi Bioscoop traces the emergence of a local culture of movie-going in the Netherlands Indies (present-day Indonesia) from 1896 until 1914. It outlines the introduction of the new technology by independent touring exhibitors, the constitution of a market for moving picture shows, the embedding of moving picture exhibitions within the local popular entertainment scene, and the Dutch colonial authorities’ efforts to control film consumption and distribution. Dafna Ruppin focuses on the cinema as a social institution in which technology, race, and colonialism converged. In her illuminating study, moving picture venues in the Indies—ranging from canvas or bamboo tents to cinema palaces of brick and stone—are perceived as liminal spaces in which daily interactions across boundaries could occur within colonial Indonesia’s multi-ethnic and increasingly polarized colonial society.