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The last forty years have witnessed the discovery of five human hepatitis viruses: hepatitis virus A, B, C, D, and E, and two related blood-borne viruses: GB virus C and TT virus. Viral Hepatitis provides a comprehensive overview of the latest developments and research studies in human viral hepatitis. Written by leading international scientists in the field, this book covers topics ranging from the history of these viruses to their molecular biology, diagnosis, epidemiology and control. It will be an invaluable reference source for hepatitis researchers, reference and diagnostic laboratories, clinicians, public health officers and graduate and medical students. Book jacket.
Perspectives in Virology IX: Antiviral Mechanisms is a collection of scientific papers presented at the Ninth Gustav Stern Symposium on Perspectives in Virology: Antiviral Mechanisms, held at Notre Dame, Indiana in February 1974. The majority of the papers in this volume concentrate on the different ways the human body defends itself against viral attack. Others deal with artificial means of interfering with the life cycle of viruses. Topics covered in this compendium include defective interfering (DI) particles as antiviral agents; detection and identification by immune electron microscopy of fastidious agents associated with respiratory illness, acute nonbacterial gastroenteritis, and hepatitis A; and synthetic vaccines. Cellular immune response in viral infections; transfer factor and cellular immunity to viral infection; and studies on adenine rabinoside are presented as well. Virologists, microbiologists, pathologists, pharmacologists, and researchers in the fields of medicine and pathology will find the book insightful and informative.
This latest volume provides a comprehensive review of the latest developments and research studies on the pathogenesis and molecular biology of human congenital infections. It reviews current diagnostic techniques and epidemiological data while describing the progress in research and understanding of continuing prevention of congenital infections and prognosis.
Animal Virus Structure provides a comprehensive, state-of-the-art summary of the structure, molecular composition, and principal antigenic and biological properties of each currently recognized family of animal viruses. Information deriving from electron microscopy, computer image processing and X-ray diffraction is integrated systematically with biochemical data into three-dimensional molecular models of viral architecture. A brief account of virus/cell interaction and pathogenicity completes each chapter.
Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control
This book is directed toward the molecular composition, pathogenesis, diagnosis, treatment and control of congenital and other related diseases of the newborn that are caused by a variety of viruses. These viruses comprise several families that include Herpesviridae (HSV-1, HSV-2, HSV-6, HSV-7, CMV and varcilla-zoster); Parvoviridae (parvovirus B19); Lentiviridae (HIV); Hepadnaviridae (HBV); Flaviviridae (HCV); and Togaviridae (RV). Leading researchers in childhood diseases and virology from Brazil, Germany, Ireland, Italy, Japan, Spain, and the United States of America report on the up-to-date advances in the molecular virology, immunology, biochemistry, pathology, diagnosis, prevalence and treatment of selected congenital and other related diseases of the newborn.* Contains recommendations for diagnosis, risk assessment, prophylaxis and treatment of viral and parasitic infections of most organisms involved in congenital diseases* An impressive list of internationally known scientists in the field of congenital diseases and related subjects
When, in late 2011, it became public knowledge that two research groups had submitted for publication manuscripts that reported on their work on mammalian transmissibility of a lethal H5N1 avian influenza strain, the information caused an international debate about the appropriateness and communication of the researchers' work, the risks associated with the work, partial or complete censorship of scientific publications, and dual-use research of concern in general. Recognizing that the H5N1 research is only the most recent scientific activity subject to widespread attention due to safety and security concerns, on May 1, 2012, the National Research Council's Committee on Science, Technology and Law, in conjunction with the Board on Life Sciences and the Institute of Medicine's Forum on Microbial Threats, convened a one-day public workshop for the purposes of 1) discussing the H5N1 controversy; 2) considering responses by the National Institute of Allergy and Infectious Diseases (NIAID), which had funded this research, the World Health Organization, the U.S. National Science Advisory Board for Biosecurity (NSABB), scientific publishers, and members of the international research community; and 3) providing a forum wherein the concerns and interests of the broader community of stakeholders, including policy makers, biosafety and biosecurity experts, non-governmental organizations, international organizations, and the general public might be articulated. Perspectives on Research with H5N1 Avian Influenza: Scientific Enquiry, Communication, Controversy summarizes the proceedings of the workshop.
Infectious diseases are an ever present threat to humans. In recent years, the threat of these emerging viruses has been greater than ever before in human history, due in large part to global travel by larger numbers of people, and to a lesser extent to disruptions in the interface between developed and undeveloped areas. The emergence of new deadly viruses in human populations during recent decades has confirmed this risk. They remain the third leading cause of deaths in the US and the second world-wide. Emerging Viruses in Human Populations provides a comprehensive review of viruses that are emerging or that threaten to emerge among human populations in the twenty-first century. It discusses the apprehension over emerging viruses that has intensified due to concerns about bioterrorism.* Presents the history of emerging viruses * Includes chapters on SARS, Pandemic Threat of Avian Influenza Viruses, West Nile Virus, Monkeypox Virus, Hantavirus, Nipah Virus and Hendra Virus, Japanese Encephalitis Virus, Dengue and Crimean-Congo Hemorrhagic Fever Viruses * Discusses surveillance for newly emerging diseases
Named a Most Anticipated Book of 2022 by Literary Hub A leading microbiologist tackles the scientific and sociopolitical impact of viruses in twelve striking essays. Invisible in the food we eat, the people we kiss, and inside our own bodies, viruses flourish—with the power to shape not only our health, but our social, political, and economic systems. Drawing on his expertise in microbiology, Joseph Osmundson brings readers under the microscope to understand the structure and mechanics of viruses and to examine how viruses like HIV and COVID-19 have redefined daily life. Osmundson’s buoyant prose builds on the work of the activists and thinkers at the forefront of the HIV/AIDS crisis and critical scholars like José Esteban Munoz to navigate the intricacies of risk reduction, draw parallels between queer theory and hard science, and define what it really means to “go viral.” This dazzling multidisciplinary collection offers novel insights on illness, sex, and collective responsibility. Virology is a critical warning, a necessary reflection, and a call for a better future.
Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author's more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. - Presents viruses within their family structure - Contains recommended journal articles with perspectives to put primary literature in context - Includes integrated recommended reading references within each chapter - Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor's manual, study guide, and test bank