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Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.
Neuropathies are one of the main neurological problems in everyday life, and they still have many partially understood parts and unknowns both for physicians and patients. Many systemic conditions may exist within them and therefore they may be difficult to treat. In this book we provide current knowledge concerning neuropathies, which we believe you will find interesting. The subject ‘’neuropathies’’ comprises a number of topics, and each and every one could be the subject of a textbook. On the other hand, this book was never designed as one. This book should be read without prejudgment because the content may not be compatible with general but repeated assumptions and guidelines. However, I believe that the book may be an inspiration for many young investigators as well. It contains current approaches and knowledge and we sincerely believe and hope that it will answer your queries regarding new perspectives about neuropathy in general.
The new Companion to Peripheral Neuropathy: Illustrated Case Studies by Dr. Peter J. Dyck, et al, which supplements Dyck and Thomas’ authoritative and comprehensive Peripheral Neuropathy, features illustrated case studies that explore the evaluation and management of the most common peripheral nerve disorders. Leading authorities in the field contribute clues to the diagnosis, clinical features, imaging studies, histopathology and more for each case. You’ll gain new insights into the causes of peripheral nerve disorders to help you diagnose and treat every condition. Offers new insights in clinical and electrophysiologic characterization, imaging, histopathology, and molecular genetics Shows you how abstract diagnosis and management principles apply in real situations Presents more illustrations than any competing reference so you can see disorders as they present in practice Offers expert clues to help you diagnose and manage patients quickly and effectively Provides references to the most significant literature in the field so you can stay at the forefront of this science
Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. Covers both hereditary and cryptogenic neurologic disorders Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Featured as a single volume, this is a comprehensive guide to possible nerve entrapment syndromes and their management. Each chapter covers a single nerve, or group of closely related nerves, and goes over the clinical presentation, anatomy, physical exam, differential diagnosis, contributing factors, injection techniques, neurolytic/surgical techniques, treatments of perpetuating factors, and complications. Nerve entrapments can occur throughout the body and cause headaches, chest pain, abdominal pain, pelvic pain, low back pain, and upper and lower extremity pain. As an example, one of the most common forms of nerve entrapment syndrome, Carpal Tunnel Syndrome, affects roughly 1 in 20 people in the United States, and is only one of several types of entrapment syndromes possible for the median nerve. Chapters are also extensively illustrated and include 3D anatomical images. The additional online material enhances the book with more than 50 videos - at least 2 for each nerve. This enables readers to easily navigate the book. In addition to a conventional index it includes a “Pain Problems Index” for searching by symptom. Peripheral Nerve Entrapments: Clinical Diagnosis and Management is a long-needed resource for pain physicians, emergency room physicians, and neurologists.
Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998, greater understanding of the the molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain has been achieved. This second edition has been fully updated in line with new clinical knowledge, and also incorporates the extensive study of thousands of surgical case studies spanning repairs of the supraclavicular plexus in the adult, the birth lesion of the brachial plexus,compound nerve injury and iatrogenous injury. Beginning with the fundamentals of the anatomy and function of the peripheral nervous system, and working its way through various types of injury, operative methods, the regeneration and recovery of nerves, surgical reconstruction, pain, and rehabilitation, this eloquently written work provides the reader with the solid understanding required to successfully perform surgery on the peripheral nervous system. Dr Shelagh Smith, joined by Dr Ravi Knight, has rewritten the chapter Electrodiagnosis. Professor Tara Renton has written a new chapter on injuries to the trigeminal nerve in maxilla-facial and dental work. The drawings, by Mr Philip Wilson, are new. Most of the 700 illustrations are also new. This thorough and authoritative look at the surgical treatment of the peripheral nerves is fully illustrated throughout with exquisite line diagrams and clear, instructive photographs.
Peripheral Nerve Disorders: Pathology and Genetics is a definitive, clinically-oriented guide to the pathology of peripheral nerve disorders. These commonly seen neurological challenges have many causes and accurate diagnosis is often necessary via pathological analysis. New techniques exploiting molecular biological knowledge have opened up new vistas to understanding the pathogenesis of these disorders, and hence their effective management. This new title takes a disease-oriented approach to understanding the pathology of these conditions. It combines classical and contemporary techniques to enable practitioners in neurology and neuropathology to better understanding of the disease processes underlying patients’ presentations and to formulate appropriate management plans. Peripheral Nerve Disorders: Pathology and Genetics is a valuable resource for neurologists, neuropathologists, pathologists, neurobiologists and geneticists.
Nerves and Nerve Injuries is a must-have for clinicians and researchers dealing with the Peripheral Nervous System and neuropathy. An indispensable work for anyone studying the nerves or treating patients with nerve injuries, these books will become the ‘go to’ resource in the field. The nerves are treated in a systematic manner, discussing details such as their anatomy (both macro- and microscopic), physiology, examination (physical and imaging), pathology, and clinical and surgical interventions. The authors contributing their expertise are international experts on the subject. The books cover topics from detailed nerve anatomy and embryology to cutting-edge knowledge related to treatment, disease and mathematical modeling of the nerves. Nerves and Nerve Injuries Volume 2 focuses on pain, treatment, injury, disease and future directions in the field. This volume also addresses new information regarding neural interfaces, stem cells, medical and surgical treatments, and medical legal issues following nerve injury. Most up-to-date comprehensive overview available on nerves and nerve injuries Comprehensive coverage of nerve injuries on bones, joints, muscles, and motor function; and offers an approach to the treatment of nerve injuries Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available Covers surgical exposure of the nerves including technical aspects of nerve repair and medicinal treatment of nerve injuries Discusses the future of our understanding of the nerves including axonal modeling, synthetic interfaces and brain changes following nerve injury
This issue of Clinics in Geriatric Medicine, guested edited by Peter Jin, focuses on Peripheral Nerve Disease in the Geriatric Population. Topics include, but are not limited to: A clinical approach to diseases of peripheral nerve, Electrodiagnostic testing for disorders of peripheral nerves, The role of imaging for disorders of peripheral nerve, Common compression mononeuropathies, Diabetes and Peripheral Nerve Disease, When is it not just diabetic polyneuropathy? Findings in atypical polyneuropathies, Small Fiber Neuropathy in the Elderly, Cancer and peripheral nerve disease, Paraproteinemias and Peripheral Nerve Disease, Guillain-Barre Syndrome and other acute polyneuropathies, Chronic Immune-mediated Polyneuropathies, Immunotherapy for Peripheral Nerve Disorders, Management of Neuropathic Pain in the Geriatric Population, and more.