Download Free Perinatal Stem Cells Book in PDF and EPUB Free Download. You can read online Perinatal Stem Cells and write the review.

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton's jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. - Explores current clinical and pre-clinical application of stem cells derived from perinatal sources - Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment - Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells - Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells
Discover how perinatal stem cells may prove to be a more powerful therapeutic tool than embryonic stem cells Normally discarded as medical waste, perinatal stem cells are an incredible source of stem cells and are gaining phenomenal research attention for their potential to become a more powerful alternative to the controversial embryonic stem cells. In response to this growing field, this book provides a thorough tutorial on the current state of the art in perinatal stem cells. Presented by a panel of authorities whose expertise reaches from research to hematology to tissue engineering and beyond, this important volume covers all of the sources of stem cells found throughout pregnancy, revealing the underlying biology and potential therapeutic uses of each: Post-gestational maternal peripheral blood Umbilical cord blood Wharton's jelly Amniotic fluid Amnion lining the amniotic cavity Umbilical vein Chorionic mesenchymal stromal cells Multi-potent cells Placenta stem cells This book is a bountiful source for researchers, graduate students, cell biologists, gene therapists, obstetricians and gynecologists, and professionals engaged in regenerative medicine and developmental biology.
Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. - Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs - Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs - Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world
This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.
Long regarded as biological waste, the placenta is gaining momentum as a viable product for clinical use. Due to their unique properties, placental cells and derivatives show great promise in curing various diseases. Utilizing contributions from world-renowned experts, Placenta: The Tree of Life considers the therapeutic potential of these cells. I
The first authoritative yet accessible guide to this controversial topic Stem Cell Research For Dummies offers a balanced, plain-English look at this politically charged topic, cutting away the hype and presenting the facts clearly for you, free from debate. It explains what stem cells are and what they do, the legalities of harvesting them and using them in research, the latest research findings from the U.S. and abroad, and the prospects for medical stem cell therapies in the short and long term. Explains the differences between adult stem cells and embryonic/umbilical cord stem cells Provides both sides of the political debate and the pros and cons of each side's opinions Includes medical success stories using stem cell therapy and its promise for the future Comprehensive and unbiased, Stem Cell Research For Dummies is the only guide you need to understand this volatile issue.
This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.
Innovations and Frontiers in Neonatology provides up-to-date information for clinicians and scientists interested in perinatal medicine. Neonatal transition, neonatal medicine from a global perspective, aspects of care including nutrition, respiratory and temperature management, resuscitation, family-centered approaches, and problems of the term newborn are covered as are complications and long-term consequences of preterm birth. Should we ventilate and how? What are the lifelong consequences of being born too small? How can we protect the neonatal brain? Can we actively influence the microbiome? Can we achieve individualized medicine with the help of metabolomics, for example? Are stem cells the miracle cure? These are just a few of the questions that world experts cover in this book while, at the same time, they take a look at the future of neonatal medicine.
Offers readers an understanding of the development of neural crest cells, which is crucial as many birth defects and tumours are of neural crest origin. Delving into stem cells from different locations of the body, this book explores the best possible source of such cells for the use in medical applications.
Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.