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This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.
The thoroughly updated Fifth Edition of Pediatric Neuroimaging is a highly illustrated text-reference that describes and illustrates the full range of pediatric disorders diagnosable by modern neuroimaging. Covering the diagnosis of brain, spinal, and head and neck disorders in the pediatric patient, the text is rooted in the principle that the proper interpretation of studies requires the acquisition of high-quality images and an understanding of the basic concepts of neuroembryology, normal development, and pathophysiology. Much coverage is given to the disorders seen in everyday practice. The emphasis is on CT and MRI, which are the optimal imaging modalities in children. The first two chapters describe useful imaging techniques in this patient population and the imaging manifestations of normal development, to distinguish that from manifestations of disease. The final ten chapters of the book are divided by groups of diseases, with numerous drawings and images that illuminate the underlying pathologic and embryologic/genetic bases of each disorder. The goal is provide a basic approach to groups of diseases, then offer detailed information about the clinical manifestations, underlying biochemistry, molecular biology, genetics and/or pathology of specific disorders. The book incorporates the essential concepts for obtaining good images and understanding normal development, which helps the reader to distinguish normal developmental changes from disease
MR Imaging and Spectroscopy of the Developing Brain.- Congenital Malformation of the Brain.- Inherited Neurological Diseases and Disorders of Myelin.- Acquired Toxic and Metabolic Brain Disorders.- Tumors: Paratentorial Neoplasms.- Tumors: Supratentorial Neoplasms.- Brain Damage.- Miscellaneous.- Vascular Abnormalities.- Temporal Bone.- Spine.- Fetal Imaging.
Covers each physiological MR methodology and their applications to all major neurological diseases.
This exhaustive text covers all aspects of diagnosis and endovascular treatment of neurological and neurosurgical diseases of the pediatric central nervous system starting from their in utero expression. It also includes the vascular malformations of each district and their endovascular treatment. Besides the "normal" imaging techniques the advanced techniques (spectroscopy, diffusion, perfusion, and functional imaging) are covered in detail. Several topics that are often only superficially dealt with in other books are herewith covered in outstanding detail. The volume is richly illustrated with high-quality neuroradiological images, with pathological correlation where applicable. The rich analytic index makes it an easily usable tool in the everyday clinical practice. The book serves both as a reference for specialists (neuroradiologists, radiologists, neurosurgeons, neurologists, pediatricians) and as a teaching text for residents and fellows-in-training.
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Destined to become the new benchmark among reference books for neuroradiology, this book is unique in its coverage of all imaging modalities and techniques used in modern imaging of the nervous system, head, neck and spine. Also discussed are the principles that underlie CT and MR imaging.
Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilepsy centers worldwide.
Every page crafted by a collaborative team of pediatricians and pediatric radiologists, this unique title by Drs. A. Carlson Merrow, Jr. and Selena Hariharan is a practical, superbly illustrated reference designed specifically for today's pediatrician. An ideal roadmap to the fast-changing landscape of diagnostic imaging tests, Imaging in Pediatrics not only guides you through the radiologic work-up of common pediatric disorders, but also translates the appearance and language of the work-up results for more effective communication between the pediatrician and the radiologist, resulting in enhanced understanding and better patient care. - Uses easy-to-read, bulleted text to highlight the most important facts about each disorder and its associated etiology, imaging work-up, clinical manifestations, and therapy. - Covers 248 diagnoses likely seen in practice, logically organized by anatomic region. - Helps you determine which studies to order and demonstrates and explains typical findings in accessible language. - Provides expanded coverage of key topics, including the imaging work-up of appendicitis that relies on ultrasound and MR over CT; new guidelines on vesicoureteral reflux and urinary tract infections; up-to-date recommendations on imaging in nonaccidental trauma, foreign body removal, and obesity-related diseases; revised nomenclature on pediatric lung diseases, vascular malformations, and neoplasms; and guidance on limiting the use of ionizing radiation in evaluating pediatric diseases. - Includes an imaging glossary, introductory prose chapters with general guidelines on imaging specific organ systems, and numerous illustrations depicting complex anatomic and pathologic relationships of individual entities.
N-acetylaspartate (NAA), the acetylated form of the amino acid aspartate, is one of the most highly concentrated chemicals in the brains of humans, yet its function remains elusive. NAA is used in nonsurgical analyses of nerve cell dysfunction, and it is implicated in a disorder known as Canavan’s disease. This book reviews research from around the world in the study of NAA, and the roles it plays in neuronal development and functioning.