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As today's organizations are capturing exponentially larger amounts of data than ever, now is the time for organizations to rethink how they digest that data. Through advanced algorithms and analytics techniques, organizations can harness this data, discover hidden patterns, and use the newly acquired knowledge to achieve competitive advantages.Pre

Report

United States. National Advisory Committee for Aeronautics

Published: 1956

Total Pages: 40


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Despite great advances in diagnosis and treatment that we witnessed in the last decades, over a billion people suffer from both respiratory and neurological diseases each year, which poses great threats to the public health and economic burden worldwide. In many instances, the underlying pathogenic mechanisms are still poorly understood, which significantly limits the efficacy of therapeutic methods. In this regard, lines of evidence pinpoint the important role of immunity and inflammation in both respiratory disorders (e.g., pulmonary hypertension, chronic obstructive pulmonary disease, asthma, etc.) and neurological ones (e.g., neurodegenerative diseases, stroke, depression, etc.). The accumulation of inflammatory cells and an excess of cytokines and chemokines at the inflammatory site would result from the disturbance of the body's delicate balance between immunity and tolerance. Therefore, it gives rise to chronic inflammation and autoimmunity underlying the development of both lung and neurological diseases. Furthermore, the inflammation interaction between lung and brain has been identified, suggesting the existence and importance of the lung-brain axis in the regulation of immune responses in the lung and brain that contribute to the onset and progression of both respiratory and neurological diseases. Nevertheless, inflammatory or immunity related risk factors as well novel targets and therapies against inflammation or immunity help early diagnosis and treatment of respiratory and neurological diseases. At present, the full picture of the molecular mechanisms of how immuno-inflammatory activation and the immune cells orchestrate the tissue remodeling leading to respiratory and neurological diseases remains unclear. The identification of inflammatory molecules as therapeutic targets or biomarkers are worth further scrutiny to halt the disease progression and monitor the therapeutic interventions.
These proceedings are the result of a three-day meeting held in Oogliani (Italy), on October 2-4 2003, whose title was "VIrtual Astrophysical Jets 2003". Our goal in convening this meeting was to gather some of the scientists among the most active in the field of numerical simulations and modelling of astrophysi cal jets. For keeping the participants close to the "real world", we also invited a few observers to give up-to-date reviews outlining the state-of-the-art of jet observations. The principal aim of the meeting was thus to present and critically discuss the state-of-the-art numerical simulations, analytical models and laboratory ex periments for reproducing the main aspects of astrophysical jets and compar ing them with observations. The discussion has been focused on the following topics: • Observations and intepretions of jets from young stars and AGNs, comparisons of models with observations; • MHO accelerations of jets: steady self-similar models, MHO numerical simula tions of time-dependent accelerations mechanisms; • Jet stability and interaction with the ambient: formation of knots in YSO jets, jet survival to instabilities, deceleration of relativistic jets in FRI sources, simulations of jets-IGM interactions, jets propagation and galaxy formation; • Numerical codes and their validation: relativistic MHO codes, comparisons among different numerical schemes, jets in the laboratory and code validation. These topics have been discussed intensively during the meeting, and the out come of these discussions is presented in this volume. The contributions have been divided in five sections.
The seventh edition of the Drilling Data Handbook was published in 1999. We are in a new communication techniques have considerably evolved. The electronic hardware and soft communication anywhere in the world, access to huge databases, as well as permanent documents required by the drilling personnel. At the moment of making a decision about Drilling Data Handbook, the question was: is it pertinent to do an electronic version on accessible one with a connection to different sites, or to keep the popular concept of the people have been using it for decades? The Internet gives access to an infinite volume everybody has experimented the trouble of being lost in the way, or the difficulty to read information. The Drilling Data Handbook does not want to compete with the web sites on other sources of electronic documentation. The main goal of our contribution to the drill access very quickly and without any additional resources to the fundamental data at the floor. That is the reason why we made the decision to present you this reviewed and up the formula you are familiar with, and we hope that it will continue to help you when play well.
Water has become one of the most important issues of our time intertwined with global warming and population expansion. The management of water supplies and the conservation of water resources remains one of the most challenging yet exciting issues of our time. Water and wastewater treatment technologies are constantly evolving creating an increasingly sustainable industry that is one of the world's largest and most interdisciplinary sectors, employing chemists, microbiologists, botanists, zoologists as well as engineers, computer specialists and a range of different management professionals. This accessible student textbook introduces the reader to the key concepts of water science and technology by explaining the fundamentals of hydrobiology, aquatic ecosystems, water treatment and supply, wastewater treatment and integrated catchment management. This fourth edition is extensively changed throughout, with new coverage of the effects of climate change, environmental assessment, sustainability and the threat to biodiversity. The text serves as a primer for both undergraduate and graduate students in either science or engineering who have an interested in freshwater biology/hydrobiology or environmental engineering. It is also useful as a unified transitional course for those who want to span the traditional areas of engineering, biology, chemistry, microbiology or business. Professionals and consultants will also find the book a useful reference.