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This book is based on reviews and research presentations given at the 16th Rochester International Conference on Environmental Toxicity, entitled liThe Cytoskeleton: A Target for Toxic Agents," held on June 4, 5 and 6 in 1984. The conference provided an in-depth discussion of the effects a~d mechanism of action of some toxic agents on the cytoskeleton. Mamma"lian and other eukaryotic cells contain protein networks within the cytoplasm comprised of microfilaments, intermediate Hlaments and microtubules. These components of the cytoskeleton playa key role in cell shape, motility, intracellular organization and transport, and cell division. Furthermore, the cytoskeleton, via associations with the cell membrane, appears to function in intracellular communication and cellular responses to membrane events. Because of the complex functional roles of the cytoskeleton which vary with cell type, degree of differentiation, and cell cycle, its disruption may result in a variety of cellular changes. This expanding field in cell biology has already attracted the interest of toxicologists and environmental health scientists as a potentially fruitful area of research. Indeed, there is mounting evidence that certain toxic and chemotherapeutic compounds, as well as physical agents such as radiation and hydrostatic pressure, disrupt the normal structure and function of the cytoskeleton. This may be an important step in the overall expression of their action. It was, therefore, an opportune time to hold a conference to encourage the development of this area of toxicology and to suggest directions for future research.
This book was first published in 1991. It considers the concepts and theories relating to mostly aqueous systems of activity coefficients.
The Handbook of Plant Ecophysiology Techniques you have now in your hands is the result of several combined events and efforts. The birth of this handbook can be traced as far as 1997, when our Plant Ecophysiology lab at the University of Vigo hosted a practical course on Plant Ecophysiology Techniques. That course showed us how much useful a handbook presenting a bunch of techniques would be for the scientists beginning to work on Plant Ecophysiology. In fact, we wrote a short handbook explaining the basics of the techniques taught in that 1997 course: Flow cytometry to measure ploidy levels, Use of a Steady-State porometer to measure transpiration, In vivo measure of fluorescence, HPLC analysis of low molecular weight phenolics, Spectrophotometric determinations of free proline and soluble proteins, TLC polyamines contents measures, Isoenzymatic electrophoresis, Use of IRGA and oxygen electrode. That modest handbook, written in Spanish, was very helpful, both for the people who attended the course and for other who have used it for beginning to work in Plant Ecophysiology. The present Handbook is much more ambitious, and it includes more techniques. But we have also had in mind the young scientists beginning to work on Plant Ecophysiology. In 1999 François Pellissier leaded a proposal presented to the European Commission in the Fifth Framework Program in the High Level * Scientific Conferences, including three EuroLab Courses about lab and field techniques useful to improve allelopathic research.
A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.
The book is based on the "best practices" of the UT Software Quality Institute Software Project Management certificates program. Quality Software Project Management identifies and teaches 34 essential project management competencies project managers can use to minimize cost, risk, and time-to-market. Covers the entire project lifecycle: planning. initiation, monitoring/control, and closing. Illuminates its techniques with real-world software management case studies. Authors (leading practitioners) address the pillars of any successful software venture: process, project, and people. Endorsed by the Software Quality Institute.