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The International Society on Oxygen Transport to Tissue (IS OTT) was founded in 1973 as a scientific society providing a forum for bioengineers, basic scientists (physiologists, biochemists and physicists) and clinicians (including anesthesiologists, intensive care specialists, pediatricians, neonatologists, internists, surgeons and other specialists) to facilitate the exchange of scientific information among those interested in any aspect of the transport and/or utilization of oxygen in tissues. From the ranks of its members, many fundamental discoveries and inventions have been made involving the many aspects of oxygen transport and utilization by biological tissues. The ISOTT proceed ings, now in its 14th edition, has become a standard work in the field as witnessed by the inclusion in the Science Citation Index of all volumes published so far. The 19th ISOTT Meeting was held in Cura~ao from August 24th through August 30th, 1991. The Cura~ao Meeting attracted 145 registrants and 45 accompanying persons. The format originated by Dr. Ian Llngmuir in 1985, consisting of posters ac companied by an abbreviated oral summary, was again successfully handled with slight modifications. The meeting was introduced by 6 review lectures covering the whole field of oxygen transport from bioengineering, the problem of diffusion in lung, blood and tissue through pathology of oxygen uptake in the lung, oxygen supply dependency of the critically ill to artificial oxygen carriers. A special session dealt with oxygen sup ply under ambiant pressure changes.
''In addition to a wide variety of traditional oxygen transport topics, particular areas have been selected for emphasis at the 1997 meeting, which are: Molecular and genetic techniques to study oxygen transport in health and disease Angiogenesis during hypoxia, ischemia, and development Physiological mechanisms of oxygen sensing Physiological fluctuations of cerebral blood flow, metabolism and oxygenation Near infrared and phsophorescence techniques for the assessment of blood and tissue oxygenation Advances in biotechnology of anticoagulants and blood substitutes. '' (excerpted from the Preface).
Seventeen years after the 2nd International Symposium on Oxygen Transport to Tissue, which was held in Mainz in March 1975, the local Organizing Committee and the Board of ISOTT were pleased to host the ISOTT Conference in Mainz on the Rhine again. The venue of the 20th meeting was the prestigious, fully restored Schloss Waldthausen (Waldthausen Castle) which provided a special setting for ISOTT 1992. The beautiful front view of the castle became part of the ISOTT 1992 logo. The 20th ISOTT Meeting was held in Mainz from August 26th through August 30th, 1992. The Conference attracted 200 active participants from 16 countries. The theme of this meeting emphasized oxygen transport to tumors but as in earlier meetings, essentially all aspects of oxygen transport within the body were covered as demonstrated by the manuscripts comprising this volume of the series "Oxygen Transport to Tissue". All manuscripts were reviewed. Extensive revisions were made in about 25% and modest revision in about another 30%. Because we had to compromise between the aim of rapid publication on the one hand and the need for thorough review on the other, minor errors in format and some typographical errors were not corrected. Except for some revisions, all of the original camera-ready manuscripts in this volume were prepared by the authors themselves and we greatly appreciate their cooperation.
In 1996, for its 24th scientific meeting, the International Society on Oxygen Trans port to Tissue made its third visit to the United Kingdom. The previous two meetings were held in Cambridge in 1977 and 1986, but this was the first meeting to be held "north of the border" in Scotland. It was attended by some 186 delegates and accompanying persons and there were 128 presentations. The venue was the West Park Centre, the University of Dundee's residential conference centre, and ISOTT was only the second major meeting to be held there using the new Villa accommodation. Dundee's slogan is "City of Discovery" since it became the permanent home of the Royal Research Ship Discovery which was built in the city and was used by Captain Scott on his first ex pedition to the Antarctic. The ISOTT meeting also fulfilled its promise of being a meeting of dis covery with sessions on all aspects of oxygen transport to tissue. The inclusion of a session on oxygen transport in vascular disease reflected the interests of the local participants. All of the manuscripts were reviewed both for their scientific and editorial accept ability and in some 50% of cases, revisions were requested from the authors. Some manu scripts were ultimately rejected. However, in view of the importance of producing the Proceedings as quickly as possible it is possible that some minor errors may have slipped through, for which the editors apologise.
This book comprises the proceedings from the 20th meeting of the International Symposium on Oxygen Transport to Tissue (ISOTT). This is volume 345 of a series in Advances in Experimental Medicine and Biology. The purpose is to publish the proceedings from the meeting of the ISOTT. This is an important work, providing synopses by experts in their fields of the current status of work on oxygen transport to tissue. As such, the objectives of the authors are met. The book is written for basic scientists, clinical scientists, and students with specialized interests. Each article is written by a credible author who is working on the specific topic. The quality of the book is attributable to the publication approach using photo-ready manuscripts provided by each author. The resultant differences in fonts, point size, spacing, justification, and graphics styles gives the book a lack of graphic continuity, although this is probably not important to the audience. The references are current and pertinent. The table of contents and index are adequate. The book quality is adequate. It is a logical and appropriate volume in this series. This book will serve best as a reference source for researchers. It would be a good addition to libraries. The book would probably only be of limited use for individual purchase.
First multi-year cumulation covers six years: 1965-70.
The International Society on Oxygen Transport to Tissue (ISOTT) was founded in 1973 "to facilitate the exchange of scientific information among those interested in any aspect of the transport and/or utilization of oxygen in tissues". Its members span virtually all disciplines, extending from various branches of clinical medicine such as anesthesiology, ophthalmology and surgery through the basic medical sciences of physiology and'biochemistry to most branches of the physical sciences and engineering. The seventeenth annual meeting of ISOTT was held in 1989 for four days, from July 21 to 24, at the Max Planck Institute for Experimental Medicine and the adjoining University Hospital (Klinikum), in Goettingen, Federal Republic of Germany. It attracted 147 active registrants and approximately 40 accompanying persons. The very successful format originated by Dr. Ian Longmuir in 1985, consisting of posters accompanied by an abbreviated oral summary, was continued with slight modification. Virtually all of the presentations utilized this format, with each poster session preceded by a formal discussion during which the presenter briefly reviewed the poster aided by a few slides. All posters remained in place for the entire four days of the meeting.
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