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In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Maximo Vento and Waldemar Carlo have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Monitoring and assessment of oxygenation in infants; Oxygen toxicity in neonates; New methods for non-invasive oxygen administration; Targeting oxygen in preterm and term infants starting at birth; Newborn resuscitation in settings without access to supplemental oxygen; Noninvasive versus invasive ventilatory support; Nasal SIMV versus Nasal CPAP before and after invasive ventilatory support; Is high-flow cannula inferior to CPAP for neonates?; Intermittent hypoxia: Importance; Closed-loop control of inspired oxygen in neonates: Compliance with targets; Meta-analysis oxygenation saturation targeting trials: Do infant subgroups matter?; Targets of oxygen saturation to optimize eye outcomes; Achieved oxygenation saturations and outcome in extremely preterm infants; Pulmonary hypertension in preterm infants; and Current recommendations and practice of oxygen therapy in preterm infants. Readers will come away with the latest information on oxygen therapy as they seek to utilize evidence-based recommendations to improve patient outcomes.
Along with Consulting Editor, Dr. Lucky Jain, Dr. Goudy has created a current issue that looks at ENT issues with newborns. Expert authors from top institutions have submitted clinical reviews on the following topics: Airway anomalies; Fetal evaluation and airway management; Hearing loss and failed NBHS; Aspiration and dysphagia in the new born; Cleft lip and palate; Microtia and facial anomalies; Cranial synostosis; Pierre Robin sequence; Vascular malformations; Choanal atresia and other nasal masses; Congenital neck masses; Subglottic stenosis; Tracheostomy in the newborn; and Stridor. Readers will come away with the information they need to make informed clinical decisions to improve patient outcomes.
This issue is a must-read for perinatologists and neonatologists who need current advances in treastment and interventions to improve the viability of the neonate. The Guest Editors have put together a concise monograph on the topic, offering the most current clinica review articles on the following topics: Antenatal corticosteroids: Who should we be treating?; Quality improvement strategies to improve care of women in preterm labor; Delivery at term: when, how, and why?; Detection and prevention of perinatal infection; Current strategies to prevent perinatal HIV transmission; Advances in fetal monitoring and association with outcomes; Relationship between perinatal interventions, the maternal-infant microbiome and neonatal outcomes; Understanding outcomes and counseling families at a periviable gestational age; Therapeutic hypothermia - how can we optimize this therapy to further improve outcomes; Reducing CPAP failure in extremely preterm infants; Optimizing caffeine therapy in preterm infants; Improving uptake of key perinatal interventions using state-wide quality collaboratives; Oxygen therapy in the delivery room: What is the right dose?; and Perinatal white matter injury: prevention and long-term outcomes. Readers will leave with the best evidence they need to improve outcomes.
In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Maximo Vento and Waldemar Carlo have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Monitoring and assessment of oxygenation in infants; Oxygen toxicity in neonates; New methods for non-invasive oxygen administration; Targeting oxygen in preterm and term infants starting at birth; Newborn resuscitation in settings without access to supplemental oxygen; Noninvasive versus invasive ventilatory support; Nasal SIMV versus Nasal CPAP before and after invasive ventilatory support; Is high-flow cannula inferior to CPAP for neonates?; Intermittent hypoxia: Importance; Closed-loop control of inspired oxygen in neonates: Compliance with targets; Meta-analysis oxygenation saturation targeting trials: Do infant subgroups matter?; Targets of oxygen saturation to optimize eye outcomes; Achieved oxygenation saturations and outcome in extremely preterm infants; Pulmonary hypertension in preterm infants; and Current recommendations and practice of oxygen therapy in preterm infants. Readers will come away with the latest information on oxygen therapy as they seek to utilize evidence-based recommendations to improve patient outcomes.
The Guest Editors have assembled top experts to provide the most current and clinically relevant articles devoted to Birth Asyphyxia. Articles in this issue are devoted to: Neonatal Transition After Birth; Pathophysiology of Birth Asphyxia; Perinatal Asphyxia from the Obstetrical Standpoint: Diagnosis and Interventions; Stillbirths: U.S. and Global Perspectives; Novel Approaches to Resuscitation and the Impact on Birth Asphyxia; Multiorgan Dysfunction and its Management After Birth Asphyxia; Neonatal Encephalopathy and Update on Therapeutic Hypothermia and Other Novel Therapeutics; Biomarkers in Neonatal Encephalopathy; Imaging and Other Diagnostics in Neonatal Encephalopathy; Asphyxia in the Premature Infant; The role of the NeoNeuro Unit for Birth Asphyxia; Long-term Cognitive Outcomes of Birth Asphyxia and the Contribution of Identified Perinatal Asphyxia to Cerebral Palsy; Global Burden, Epidemiologic Trends, and Prevention of Intrapartum Related Deaths in Low-resource Settings; and Neonatal Resuscitation in Low-resource Settings.
In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Jonathan M. Davis and Errol R. Norwitz have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Drugs for the prevention and treatment of preterm labor; Drugs for the prevention and treatment of hypertensive disorders of pregnancy; Drugs to promote neuroprotection; Medications that cause fetal anomalies and possible prevention strategies; Safety and efficacy of psychotropic medications during pregnancy; Treatment of viral infections during pregnancy (HIV, herpes, CMV, hepatitis C); Drugs to control diabetes during pregnancy; Cardiotonic drugs; Drugs to treat coagulation disorders in the newborn; Drugs for the prevention and treatment of bronchopulmonary dysplasia; Drugs for the prevention and treatment of neonatal brain injury; Drugs for the prevention and treatment of sepsis in the newborn; Analgesia, opioids and other drug use during pregnancy and Neonatal Abstinence Syndrome; Medications and breast feeding; Principles of pharmacokinetics in the pregnant woman and fetus; and Challenges in designing clinical trials to test new drugs in the pregnant woman and fetus. Readers will come away with the latest information on therapeutics as they seek to utilize evidence-based recommendations to improve patient outcomes.
The Guest Editors have assembled well published authors to present state-of-the-art clinical reviews devoted to resuscitation of the newborn and fetus. Articles are devoted to the following topics: fetal/intrauterine compromise; Cellular biology of end organ injury and strategies to prevent end organ injury; Role of oxygen in the DR; DR management of meconium stained infant; Role of medications in neonatal resuscitation; Delayed cord clamping; Post-resuscitation management; HIE and novel strategies for neuroprotection; Physiology of transition from intrauterine to extrauterine life; Resuscitation of preterm infants: Special considerations; Chest compressions and dysrhythmias in neonates; Resuscitation of infants with prenatally diagnosed anomalies; Ethical issues in neonatal resuscitation; Training programs in neonatal resuscitation: The Neonatal Resuscitation Program and Helping Babies Breathe; and Future of neonatal resuscitation.
In collaboration with Consulting Editor, Dr. Lucky Jain, Drs. Robert Kliegman and Bret Bordini have put together topics that provide a current clinical update on the treatment and management of undiagnosed and rare diseases in the neonate. Expert authors have contributed clinical review articles on the following topics: Neonatal Liver Failure; Neonatal Autoinflammatory Disorders; Rare or Unusual Dermatologic Disorders In Neonates; Neonatal Immune Deficiency; Congenital Diarrhea Syndromes; Nonimmune Hydrops; DNA Depletion Syndromes; Genomic Approach to Dysmorphology Syndromes; Nonimmune Anemias; Severe Metabolic Crisis (Metabolic Acidosis, Unresponsive Hypoglycemia, Hyperammonemia); Heterotaxia Syndromes; Neonatal Appendicitis; Avoiding Diagnostic Errors in Neonatology; and Differentiating Congenital Myopathy from Congenital Muscular Dystrophy. Readers will come away with the information they need to improve outcomes in the neonate.
In consultation with Dr. Lucky Jain, Consulting Editor, Drs. Dempsey and EL-Khuffash have chosen a wide range of topics in cardiovascular issues that cover new diagnostic techniques and important areas of management, including the role of volume administration, inotropes, and corticosteroids in the setting of cardiovascular instability. These remain critical questions in neonatal care, and authors were selected based on their expertise and ability to provide the reader with the most recent up-to-date evidence upon which to direct intervention. The clinical review articles in this issue will address the relationship between intervention and outcome in preterm hypotension, the management of cardiovascular instability in the setting of pulmonary hypertension and therapeutic hypothermia, and finally ask if it's time for a definitive trial in the management of PDA. The final article in the issue highlights the clinical trials to date, what trials are currently ongoing, and what the future holds in cardiovascular support for the preterm infant. The reader will come away with the most current information on this topic from international experts including Europe, Canada, USA, and Australia.
Together with Consulting Editor Dr. Lucky Jain, Dr. Sudarshan R. Jadcherla has put together a comprehensive issue devoted to neonatal gastroenterology. Expert authors have contributed clinical review articles on the following topics: Neonatal Aerodigestive Disorders: Epidemiology and Economic Burden; Feeding and Swallowing Difficulties in Neonates: Developmental Physiology and Pathophysiology; Gastroesophageal Reflux Disease in the NICU Neonate: Controversies, Current Understanding and Future Directions; Feeding Difficulties and Tube-feeding Controversies in Complex Neonates: Evidence-Based Practices; Physiology and Pathological basis of Aerodigestive Difficulties in Chronic Lung Disease; Congenital Diarrheas in Infants: Pathophysiology, Consequences, and Potential Treatment Strategies; Short Gut syndrome: Recent Advances in Pathophysiology and Intestinal Support Practices; Neonatal Cholestasis in the Premature Infant: Approaches to Diagnosis and Management; Strategies for Prevention of TPN-related Liver Injury; Supplements and Additives to Human Milk: Principles and Practices, Current Controversies; Microbiome and Gut Injury in Neonates; Recent Advances in NEC Research: Strategies for Implementation in Clinical Practice; Transfusion-Related Gut Injury and NEC; Neonatal Endoscopy, Diagnosis and Intervention Procedures Crib-side; and Surgical Gastrointestinal Emergencies in Neonates: An overview. Readers will come away with the information they need to improve outcomes in the neonate.