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Using a number of outstanding examples, this text introduces readers to the immense variety of marine natural compounds, the methodologies to characterize them and the approaches to explore their industrial potential. Care is also taken to discuss the function and ecological context of the compounds. Carefully produced and easy to read, this book serves students and professionals wishing to familiarize themselves with the field, and is ideally suited as a course book for both industry to academia.
With its integral treatment of ecosystem and resource management, this is the only overview of the field to address current thinking and future trends. All contributions have been written with the novice in mind, explaining the basics and highlighting recent developments and achievements. Unmatched in scope, this two-volume reference covers both traditional and well-established areas of marine biotechnology, such as biomass production, alongside such novel ones as biofuels, biological protection of structures and bioinspired materials. In so doing, it ties together information usually only found in widely dispersed sources to assemble a grand unified view of the current state of and prospects for this multi-faceted discipline. The combination of the breadth of topics and the focus on modern ideas make this introductory book especially suitable for teaching purposes and for guiding newcomers to the many possibilities offered by this booming field.
In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.
This book describes the state-of-the-art concerning the ‘marine microbiome’ and its uses in biotechnology. The first part discusses the diversity and ecology of marine microorganisms and viruses, including all three domains of life: Bacteria, Archaea, and Eukarya. It discusses whether marine microorganisms exist and, if so, why they might be unique. The second part presents selected marine habitats, their inhabitants and how they influence biogeochemical cycles, while the third discusses the utilization of marine microbial resources, including legal aspects, dissemination, and public awareness. The marine microbiome is the total of microorganisms and viruses in the ocean and seas and in any connected environment, including the seafloor and marine animals and plants. The diversity of microbial life remains unquantified and largely unknown, and could represent a hidden treasure for human society. Accordingly, this book is also intended to connect academics and industry, providing essential information for microbiologists from both fields.
Seaweeds around the World: State of Art and Perspectives, Volume 95, includes discussions on current research conducted in the field of algae. Specific chapters cover Isotopic Labeling of Cultured Macroalgae and Isolation of 13C-labeled Cell Wall Polysaccharides for Trophic Investigations, Selected Red Seaweeds from the Philippines with Emerging High-Value Applications, Challenges to the Future Domestication of Seaweed Cultivated Species: Understanding Individual Needs and Physiological Processes for Large-Scale Production, The Importance of Mucilage in Dispersion and Efficiency of Fertilization of Male Gametes, The Application of Seaweeds in Environmental Biotechnology, Indonesian Sargassum Species Prospecting: Potential Applications of Bioactive Compounds, and much more.
The book features comparative perspectives on the field of chemical ecology, present and future, offered by scientists from a wide variety of disciplines. The scientists contributing to this book –biologists, ecologists, biochemists, chemists, biostatisticians – are interested in marine, freshwater and terrestrial ecosystems and work on life forms ranging from micro-organisms to mammals, including humans, living in areas from the tropics to polar regions. Here, they cross their analyses of the present state of chemical ecology and its perspectives for the future. Those presented here include complex, multispecies communities and cover a wide range both of organisms and of the types of molecules that mediate the interactions between them. Up to now, no book has presented a solid scientific treatment of a wide range of examples. This book illustrates a diverse panel of the most advanced aspects of this rapidly expanding field.
Oceans include the greatest extremes of pressure, temperature and light, and habitats can range from tropical waters to ocean trenches, several kilometers below sea level at high pressure. With its 70% of the surface of our planet marine ecosystem still remains largely unexplored, understudied and underexploited in comparison with terrestrial ecosystems, organisms and bioprocesses. The biological adaptation of marine organisms to a wide range of environmental conditions in the specific environment (temperature, salinity, tides, pressure, radiation, light, etc.) has made them an enormous reservoir of interesting biological material for both basic research and biotechnological improvements. As a consequence marine ecosystem is valued as a source of enzymes and other biomolecules exhibiting new functions and activities to fulfill human needs. Indeed, in recent years it has been recognised as an untapped source of novel enzymes and metabolites even though, with regard to the assignment of precise biological functions to genes, proteins and enzymes, it is still considered as the least developed. Using metagenomics to recover genetic material directly from environmental samples, this biogenetic diversification can be accessed but despite the contributions from metagenomic technologies the new field requires major improvements. A few words on the complexity of marine environments should be added here. This complexity ranges from symbiotic relationships to biology and chemistry of defence mechanisms and from chemoecology of marine invasions up to the strategies found in prokaryotes to adapt to extreme environments. The interdisciplinary study of this complexity will enable researchers to find an arsenal of enzymes and pathways greatly demanded in biotechnological applications. As far as marine enzymes are concerned they may carry novel chemical and stereochemical properties, thus biocatalytically oriented studies (testing of suitable substrates, appropriate checking of reaction conditions, study of stereochemical asset of catalysis) should be performed to appropriately reveal this “chemical biodiversity” which increases interest for these enzymes. Among other biomolecules, polysaccharides are the most abundant renewable biomaterial found on land and in oceans. Their molecular diversity is very interesting; except polysaccharides used traditionally in food and non-food industries, the structure and the functionality of most of them are unknown and unexplored. Brown seaweeds synthesize unique bioactive polysaccharides: laminarans, alginic acids and fucoidans. A wide range of biological activities (anticoagulant, antitumor, antiviral, anti-inflammation, etc.) have been attributed to fucoidans and their role with respect to structure-activity relationship is still under debate. In this Research Topic, we wish to centralize and review contributions, idea and comments related to the issues above. In particular results of enzymatic bioprospecting in gross marine environment will be acknowledged along with research for structural characterization and biological function of biomolecules such as marine polysaccharides and all kind of research related to the complexity of bioprocesses in marine environments. Inter- and multi-disciplinary approach to this field is favoured in this Research Topic and could greatly be facilitated by the web and open access nature as well.
This book is a printed edition of the Special Issue "Biological Activity of Natural Secondary Metabolite Products" that was published in IJMS
The forces of natural selection have been a primary driver in the evolution of adaptive animal behaviours. On the one hand animals must evade predation in order to survive and pass on their genes; on other hand, and for the same underlying reasons, animals must also be capable of successfully capturing prey. This situation has led to an evolutionary arms race in which predator and prey are locked in the battle to survive. A common strategy in each situation is to enhance the speed of response, resulting in the evolution of neural, muscular and biomechanical designs that produce supremely fast and eye-catching behavioral responses. The aim of this book is to illuminate the design principles of escape and predatory behaviours using a series of case histories from different animal groups and to emphasize the convergent evolution of neural circuitry that optimizes the chances of survival. Using these case histories the authors describe sensory mechanisms that aid prey and predator detection, central neural circuit designs that increase speed of response and neuromuscular and biomechanical properties that aid the performance of escape and predatory movements.
This book illustrates the role of photoprotective and radioprotective metabolites from natural sources. Various classes of radioprotective metabolites derived from cyanobacteria, algae, fungi, bryophytes, pteridophytes, gymnosperms, and higher plants have been explained to reinforce the current knowledge in this field. In addition, the book elucidates the potential applications of these metabolites in pharmaceutics, cosmetics, and biomedical sciences that will help develop commercial products in modern anti-radiation therapeutics. Topics such as stress tolerance environmental strategies, evolutionary tendency, and biosynthetic route of radioprotective compounds for cost-effective large-scale industrial production of the metabolites are also covered in the book. This book will add to the understanding of radioprotective mechanisms and curative measures for various deleterious diseases leading to cancer development. This volume also offers the latest insights into current and upcoming issues that arise from solar and atomic radiations and their amelioration by inherent radioprotective mechanisms of green plants. This book benefits readers from academia, industry, colleges, and research students to better understand the impacts of various radiations and the development of radioprotective green compounds.