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Oral squamous cell carcinoma (SCC) is the 13th commonest cancer worldwide, and the most common cancer in the Asian subcontinent due to the widespread habit of tobacco and betel nut chewing. Despite many advances in diagnosis and treatment, the survival statistics have only marginally improved. However our understanding of the disease process and transformation from pre-cancerous lesions of the oral mucosa to an invasive SCC cancer and their progression has expanded exponentially. There are many conditions of the oral mucosa that can progress to an invasive malignancy. A thorough understanding of these conditions is a prerequisite for all those involved in the management of the diseases of the oral mucosa and head and neck region. The recognition and timely treatment of potentially pre-malignant conditions of the oral cavity can minimize the change to an overt malignancy in many patients through patient education, appropriate treatment and surveillance. In this book we cover relevant anatomy, biology, diagnosis and latest management strategies for pre-cancerous conditions that affect the oral mucosa. The respective chapters are written by expert contributors from around the world, lending the book a global perspective and making it an essential guide for all those involved in the management of pre-malignant lesions arising in this challenging anatomical region.
A multidisciplinary approach to the problems related to the diagnosis, treat ment, and rehabilitation of patients with oral cancer and precancer is reflected in the various specialties of the authors who contributed to this book. Today, patients with tumors of the oral cavity are dealt with preferably by a team of specialists who have been properly trained in the field of oncology, who have learned to appreciate each other's knowledge and experience, and who are able to operate as an integrated team. This book is intended for use by every physician and dentist involved in the diagnosis and management of oral cancer. It is 'presented in such a way as to be useful for both the physician in training as well as the specialist in the field of head and neck oncology. The text concentrates on the common as well as the unusual aspects. For those who look for more detailed information, an exten sive list of references is provided at the end of each chapter. It should be emphasized that treatment policies may vary not only in differ ent parts of the world, but also from institution to institution, depending on the expertise of the members of the oncologic team and the available facilities. I. VAN DER W AAL AND G. B. SNOW, editors.
This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.
Without early detection, oral cancer is deadly. Protect your patients by applying the latest clinical interventions. Rates of new oral cancer cases continue to increase and mortality rates remain alarmingly high. Oral cancer may be preceded by clinically identifiable precancerous changes in the oral mucosa, which offer a therapeutic window of opportunity to intervene and halt disease progression to carcinoma development. Written and edited by prominent researchers in the field, Oral Precancer: Reviews current scientific research on precancer conditions of the oral cavity providing evidence-based analysis of the nature and behavior of potentially malignant and deforming oral diseases Explains the principles of prevention, diagnosis and management of potentially malignant disorders of the oral cavity Details a practical and reliable interventional treatment strategy to facilitate early diagnosis and effective treatment of both precancer and early invasive carcinoma Contains a chapter devoted to illustrative case histories, high-quality, color, clinical photos, reference sections in each chapter listing relevant review articles, and more From start to finish, Oral Precancer offers undergraduate students, clinicians, and professors an invaluable resource to minimise the morbidity and mortality of this most significant and life threatening of oral conditions.
This book includes more clinical aspects and concentrates on cancer and precancer of the oral mucosa rather than attempting to cover all benign and malignant tumours of the oral and oropharyngeal tissue. One main emphasis is the significance of the clinical features of the various lesions discussed. Attention is also drawn to those conditions particular to the oral mucosa that may give rise to appearances which are important in differential diagnoses but can be misleading to those who do not have detailed knowledge of the tissue involved. The TNM-classification for malignant tumours of the lip and oral cavity is also included.
Without early detection, oral cancer is deadly. Protect your patients by applying the latest clinical interventions. Rates of new oral cancer cases continue to increase and mortality rates remain alarmingly high. Oral cancer may be preceded by clinically identifiable precancerous changes in the oral mucosa, which offer a therapeutic window of opportunity to intervene and halt disease progression to carcinoma development. Written and edited by prominent researchers in the field, Oral Precancer: Reviews current scientific research on precancer conditions of the oral cavity providing evidence-based analysis of the nature and behavior of potentially malignant and deforming oral diseases Explains the principles of prevention, diagnosis and management of potentially malignant disorders of the oral cavity Details a practical and reliable interventional treatment strategy to facilitate early diagnosis and effective treatment of both precancer and early invasive carcinoma Contains a chapter devoted to illustrative case histories, high-quality, color, clinical photos, reference sections in each chapter listing relevant review articles, and more From start to finish, Oral Precancer offers undergraduate students, clinicians, and professors an invaluable resource to minimise the morbidity and mortality of this most significant and life threatening of oral conditions.
It is estimated that in India 75% of cancers of oral cavity are attributable to tobacco chewing, smoking and alcohol drinking. So the purpose of this book is to present the correlations of these premalignant disorders microscopically with in tobacco users and alcohol drinkers.
This is the first of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume, on tumor biology, epidemiology, etiology, emerging role of cancer stem cells and prevention of oral cancer, opens by discussing oral carcinogenesis in general and the role of particular carcinogens and human papillomavirus. Global epidemiology and changes in disease prevalence are then addressed. Up-to-date information is provided on emerging cancer biomarkers, and the biologic basis of personalized therapy is explained. Histopathological features of malignant and premalignant neoplasms and their relevance to management are described. Further chapters focus on the current status of chemoprevention, the management of oral submucous fibrosis, and the value of various diagnostic adjuncts. The volume concludes by critically evaluating the efficacy of oral screening methods. Volume 1: Biology, Epidemiology, Etiology, and Prevention Volume 2: Diagnosis and Management Volume 3: Oral and Maxillofacial Reconstructive Surgery Volume 4: Rehabilitation and Supportive Care