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The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.
The classic reference covering the diagnosis and treatment of all major ophthalmic diseases, as well as neurological and systemic diseases causing visual disturbance-extensively revised and updated Features State-of-the-art coverage of diagnostic techniques and therapeutic interventions for the full range of ophthalmic disorders Chapters dedicated to ophthalmic therapeutics, neuro-ophthalmology, ocular disorders associated with systemic diseases, immunologic diseases of the eye, pediatrics, genetics, preventive ophthalmology and lasers The latest clinical perspectives on such topics as: Treatments for age-related macular degeneration, including anti-VEGF therapies Intraocular steroid injections for retinal diseases Immunomodulatory drugs Treatment of corneal infections Medical and surgical treatments for glaucoma Detailed appendices on visual standards, practical factors in illumination, rehabilitation of the visually handicapped, and special services available to the blind Latest references
Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies.
Completely updated and revised, this classic book provides the essential information on ocular therapeutics for the modern optometrist. Retaining all the features that made previous editions so popular, the new fifth edition continues to provide a basic grounding in pharmacological principles and drug types, before moving on to illustrate the scope of ocular therapeutics in the management of common acute conditions affecting the anterior segment of the eye. Throughout the text there are numerous new clinical notes and ready-reference tables, making for greater ease of use than ever before. - Greatly expanded text including an illustrated section on ocular disease and its treatment - New drugs included, processes and procedures updated and revised - Now all completely redesigned in full colour throughout - Features ready-reference tables and clinical notes - Completely updated and revised to reflect modern practice - Clinically orientated and appropriate for the practitioner as well as the student - Written by experts with years of practical experience in teaching and training as well as dispensing these essential preparations - Includes a new chapter describing therapeutic uses of drugs illustrated with 18 colour plates.
The Actions and Uses of Ophthalmic Drugs: A Textbook for Students and Practitioners, Second Edition provides pertinent information in relation to concepts in pharmacology, the formulation and application of ophthalmic drugs, and adverse ocular effects of systemic medication. This book discusses the preparations used in contact lens practice. Organized into 17 chapters, this edition begins with an overview of the primary systems of drug classification according to their actions or effects, or on the basis of their chemistry. This text then presents a detailed discussion on the actions and uses of ophthalmic autonomic drugs. Other chapters consider the structure and function of the involuntary nervous system in the orbital region. This book discusses as well the two main classifications of ophthalmic drugs, namely, therapeutic and diagnostic. The final chapter deals with the clinical significance of medication-induced ocular adverse effects. This book is a valuable resource for ophthalmologists, students, and practitioners.
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Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
For those who are new to the subject, ocular pharmacology can be a difficult and sometimes overwhelming topic.nbsp; Ophthalmic Medications and Pharmacology, Second Edition is a reader-friendly guide that provides a quick review and basic clinical reference of ocular pharmacology. nbsp; In this updated and revised second edition, Drs. Duvall and Kershner present an overview to the medication and drugs found most commonly in ophthalmic practice without overwhelming those professionals new to the subject.nbsp; nbsp; Ophthalmic Medications and Pharmacology concisely reviews commonly used and prescribed medications, how they work, dosage, therapeutic use, and potential side effects.nbsp; This new edition also highlights key information for patients about the medications they encounter and are prescribed in the clinic. nbsp; Ophthalmic staff, students, and research professionals looking for an introduction and basic go-to guide will welcome having a copy of Ophthalmic Medications and Pharmacology by their side. New to this edition: ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; An appendix focused on the drug approval process. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; A chapter on retinal therapies. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; Study icons to assist in the learning process. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; New coverage of vasoconstrictors. nbsp; nbsp;