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A concise, illustrated guide to the operative techniques and medical management of liver transplantation Filled with more than 1,000 images, illustrations, and bulleted text, this invaluable book provides a highly visual approach to liver transplantations for a diverse audience of healthcare professionals who treat patients with acute and chronic liver failure that requires full or partial transplantation. With coverage of all topics in the field, this reader-friendly and practical book serves as an ideal reference for residents, fellows, and senior physicians. It is easy to read, simple, and practical. FEATURES Over 1,000 high quality images and illustrations Multi-Disciplinary Approach Overview Liver Disease - Native and Recurrent Recipient Candidate Evaluation Donor Evaluation - Live and Deceased Pharmacy Anesthesia Operative Techniques Post-Operative Management Pathology Dermatological Findings Imaging And much more, including Immunology, Ethics, Quality Control, Risk Management, and Cellular and Tissue Engineering
A liver transplant is a surgical procedure that involves the replacement of a diseased liver with a healthy liver received from a donor. It is used to treat conditions such as chronic or acute liver failure and hepatocellular carcinoma. Liver transplantation can be categorized depending on the type of donor and is broadly categorized into deceased donor liver transplants and live donor liver transplants. The most common procedure of liver transplantation is orthotopic liver transplantation (OLT). In this procedure, the original liver is removed followed by the replacement of the donor liver in the exact anatomic position. Whole organ is generally transplanted, however, segmental liver transplantation can also be done, which enables the transplantation of two recipients with a single cadaveric organ. Reduced grafts technique is commonly used for the cases having mismatch between the organ size of the recipient and the donor. This book outlines the operative techniques and medical management of liver transplantation in detail. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this area of study. The book will prove to be immensely beneficial to students and researchers in this field.
Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications. Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team. Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino. Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation. Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways. Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text. Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos.
With a strong focus on technical efficiency, Operative Techniques in Transplant Surgery takes you step by step through every aspect of solid organ transplantation surgery. Using concise text, full-color illustrations, and operative images, it provides detailed coverage of deceased and living donation, as well as liver, kidney, pancreas, and lung transplantation. You’ll find practical, step-by-step guidance on preoperative, intra-operative, and post-operative clinical decision making, helping you hone your skills and incorporate today’s innovative approaches into your surgical practice.
The book covers all aspects of peri-operative anesthetic management of liver transplant patients. It provides a comprehensive coverage of the relevant history, surgeons’, hepatologists’, intensivists’ and pediatricians’ perspective of the disease, its pathogenesis, clinical presentation and indication for transplant. It discusses the practical aspects like fluid management and use of vasopressors. The book is divided into sections for a better and comprehensive delivery of information. Individual sections provide up to date information on the pre-operative issues and optimisation, intra-operative care and management and post-operative critical care issues and management of all transplant patients with special emphasis on recent advances. Separate sections cover ICU care of these patients in great detail and anesthetic management of pediatric liver transplant. The book includes anesthetic techniques involved in conducting multiorgan transplant. It discusses clinical approach to a patient with acute liver failure, brain death criteria and laws and organ donor management. It also presents newer techniques and methodologies adopted in the field of liver transplant. It includes ample illustrations, flowcharts, key points in each chapter, figures and photographs. The book contains chapters focusing on post-transplant patients presenting for non-transplant surgery. The book fills the gap in the literature for a comprehensive guide for the anesthetist performing or pursuing liver transplant, students/trainees/examinees who have a keen interest in this field and doctors dealing with such patients in critical care, donor management, pursuing general anesthesia. It is also helpful for hepatologists, intensivists and surgeons associated with liver transplant.
This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.
This handbook comprehensively covers the areas within hepato-pancreaticobiliary surgery in a concise, readable format. It is extensively cross-referenced and illustrated, while its portable format makes it indispensible as a quick reference within the clinical arena.
Pre- and post-operative care of transplant patients is an aspect of Critical Care Medicine in which most ICU physicians and nurses have received little or no formal training and are left to cope with this complex population with only incomplete "on the job experience" as a guide. In response to this clinical knowledge gap, ICU Care of Abdominal Organ Transplant Patients provides a concise at the bedside resource fo intensivists, surgeons, and nurses caring for abdominal organ transplant patients before and after surgery. In a concise, practical style, the authors offer concrete solutions to questions and situations confronted by ICU clinicians. Chapters address general principles of immunosuppression, infectious complications, management, and nursing considerations plus indications, approach to anesthesia, transplant procedure, and post-operative course for liver, kidney, pancreas, islet cell, and small bowel and multivsceral transplantation.
Liver Transplantation: Clinical Assessment and Management is the perfect tool for all gastroenterologists, hepatologists and transplant surgeons managing patients with liver disease awaiting and undergoing transplantation. Led by James Neuberger, world experts in hepatology and transplantation provide a chronological, step-by-step approach to best clinical management and patient care. Evidence-based throughout and with reference to the very latest practice guidelines from major societies such as EASL and AASLD, the book covers: When to refer a patient for liver transplantation Selection, assessment and management on the list Transplantation for acute liver failure Donation and allocation Care of the liver transplant recipient 80 high definition videos of transplant surgery allow you to watch the experts in action and provide an outstanding visual and teaching element. In addition, key points, potential pitfalls, management algorithms, and useful weblinks all help ensure rapid reference browsing. If you're managing patients requiring a liver transplant, this multimedia resource will save you time and effort by putting essential information within easy reach.
Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Access valuable pearls, pitfalls, and insights from Dr. Ronald Busuttil and Dr. Goran Klintmalm, two of the world's preeminent experts in liver surgery. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues. Overcome your toughest challenges in liver transplantation. Many new and thoroughly revised chapters include: Deceased Organ Donation after Cardiac and Brain Death; Liver Transplantation for Non-Alcoholic Steatohepatitis; Extended Criteria Donors; Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation; Small for Size Syndrome; Dual Grafts for Transplantation; Arterial Reconstructions-Pitfalls; Transition of Pediatric Patients to Adulthood; Immunosuppressive Biologic Agents; Long Term Toxicity of Immunosuppressive Therapy; Stem Cell and Liver Regeneration; and Extracorporeal Perfusion for Resuscitation of Marginal Grafts. Stay current in your field and optimize patient outcomes with coverage of the most recent advances in living donor transplantation, pediatric transplantation, and gene and stem cell therapy. Access the latest information on anti-rejection/immunosuppressive drugs, as well as comprehensive discussions of each drug or combination of drugs used to suppress immune system.