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Alistair D'Arcy McDermott has a great mum and a great dad who love him very much ... but aren't so keen on each other. He also has a best friend with a wicked laugh and a teacher who wears tight white trousers and likes humiliating kids. So when his mum decides that she's going on a blind date with the teacher from hell, Burke the Jerk, Al's worst nightmare has come true. And when she tells him that they're going on holiday with her new man, Al's got to do something drastic. He packs his bag of total destruction and heads off for the holiday of a lifetime ...
Alastair D'Arcy McDermott - otherwise known as Al - is less than thrilled at his holiday project: helping out at the local old people's home. How did he end up getting stuck with old Violet Rose and batty Major Maddocks? But then he meets the sinister Mrs Black, and the fun begins - Al's on his greatest mission yet ... And don't miss the first story of Al's adventures, OPERATION ITCHY BUM.
Boyface Antelope has been waiting his whole life to turn ten and be allowed to enter his parents' stripemongering shop so he can take stripes off animals and put them on something different. Like tartan onto badgers, or removing the stripes of zebras to make ponies. On the morning of his tenth birthday he finds his parents ill, and they ask him not just to go in the shop but to look after it on his own! Will he be able to keep the stripemongery running smoothly?
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Aunt Edna has created a no-nonsense nanny android to make sure Billy and Alfie don't have any fun. But then Alfie discovers how to override Auntie Anne-Droid's programming and nothing can stop them eating all the Cheeki Choko Cherry Cakes they like ... until the real aunt Edna is kidnapped!
Join Secret Agent Barker on his crazy quest to rid the world of megafleas. Lift the flaps, fold out pages. Humorous. 4 yrs+
The ASCRS Textbook of Surgery of the Colon and Rectum offers a comprehensive textbook designed to provide state of the art information to residents in training and fully trained surgeons seeking recertification. The textbook also supports the mission of the ASCRS to be the world’s authority on colon and rectal disease. The combination of junior and senior authors selected from the membership of the ASCRS for each chapter will provide a comprehensive summary of each topic and allow the touch of experience to focus and temper the material. This approach should provide the reader with a very open minded, evidence based approach to all aspects of colorectal disease. Derived from the textbook, The ASCRS Manual of Surgery of the Colon and Rectum offers a “hands on” version of the textbook, written with the same comprehensive, evidence-based approach but distilled to the clinical essentials. In a handy pocket format, readers will find the bread and butter information for the broad spectrum of practice. In a consistent style, each chapter outlines the condition or procedure being discussed in a concise outline format – easy to read, appropriately illustrated and referenced.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
This book is not about poetry; it is simply a book to read while one relieves him or herself in the latrine, bathroom, head, or toilet, while taking a crap, dropping a stool, pinching a loaf, dropping the kids off at the lake, I could go on, but I am sure you get the picture. There are quotes from the stalls of many bathroom walls found all over the world. Now since I am male, I did not have a chance to visit many, if any, female bathrooms (sorry, ladies), so I do not have many quotes from said places. Some subject material may be offensive. Please read with cautious trepidation. Some are personal quotes, things that pop into my brain at any given moment. Sometimes these thoughts are followed by bouts of laughter that cause people that are standing near me to think that I am strange. They usually react by walking away fast. But I decided to add these thoughts to Bathroom Poetry anyways. Some quotes are famous and semifamous quotes. Some are unknown author quotes. Many of the quotes were found on the stalls of bathrooms from all over the globe. I have collected many quotes from memory during my travels around the world while serving twenty-one years in the United States Navy. This book is meant for entertainment value only. Any words of wisdom gleaned while reading this book is pure shit-house luck.