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Due to the complexity and interconnectivity of many biological processes, an integrative systems biology approach is required to better understand them. The integration of various omics data (including genomics, proteomics, transcriptomics, and metabolomics data) will provide a holistic view that highlights the relationship among the various biomolecules and their functions in plant growth, resistance, quality, and many other important traits. Recent advances in analytical power and in the ability to process large data sets has enabled researchers to integrate multi-omics data and have a much deeper knowledge of the cell, tissue, organ, or even an entire organism being studied. The goal of this Research Topic is not only to publish high-quality and reliable omics data but also to answer the bigger question of how to integrate and correlate different data sets from multiple omics studies. Can one omics data set be used as a primary data set for the design and execution of another omics study? If so, then how it can be done? What are its pre-requisites? How can we plan research involving multi-omics approach to reach a meaningful conclusion? These are the questions that need our attention and their answers are critical for the future of omics-based research. For this Research Topic, we welcome contributors to submit manuscripts related to the following themes: • Studies on plant-based genomics, transcriptomics, proteomics, and metabolomics; • Development of new analytical methods for omics utilizing in plants; • Advancements in the current analytical methods for utilizing omics in plants; • Integration of multi-omics data sets; • Development of new statistical methods for data analysis.
In the post-genomic era, several plant species have been sequenced and massive genomic information is now available which contributed to expand the development of novel technical strategies for the study of additional levels of biological information of plant species. This book focuses on the “omics” approaches together with systems analysis of several different plant species, which have revealed very interesting variations on the cellular responses at the protein, transcript and metabolite levels in response to changes environmental conditions. The volume covers recent technological advances in the area of “omics” and synthesizes recent findings of the field of plant “omics” and systems biology together along with techniques that can be applied for such studies.
Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic ‘step by step’ manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to ‘translational research’, i.e., drug discovery, drug target prediction, and precision medicine Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways
PlantOmics: The Omics of Plant Science provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next generation sequencing, functional genomics, cyto-metagenomics, epigenomics, miRNAomics, proteomics, metabolomics, glycomics, lipidomics, secretomics, phenomics, cytomics, physiomics, signalomics, thiolomics, organelle omics, micro morphomics, microbiomics, cryobionomics, nanotechnology, pharmacogenomics, and computational systems biology for plants. It provides up to date information, technologies, and their applications that can be adopted and applied easily for deeper understanding plant biology and therefore will be helpful in developing the strategy for generating cost-effective superior plants for various purposes. In the last chapter, the editors have proposed several new areas in plant omics that may be explored in order to develop an integrated meta-omics strategy to ensure the world and earth’s health and related issues. This book will be a valuable resource to students and researchers in the field of cutting-edge plant omics.
Computational and high-throughput methods, such as genomics, proteomics, and transcriptomics, known collectively as “-omics,” have been used to study plant biology for well over a decade now. As these technologies mature, plant and crop scientists have started using these methods to improve crop varieties. Omics in Plant Breeding provides a timely introduction to key omicsbased methods and their application in plant breeding. Omics in Plant Breeding is a practical and accessible overview of specific omics-based methods ranging from metabolomics to phenomics. Covering a single methodology within each chapter, this book provides thorough coverage that ensures a strong understanding of each methodology both in its application to, and improvement of, plant breeding. Accessible to advanced students, researchers, and professionals, Omics in Plant Breeding will be an essential entry point into this innovative and exciting field. • A valuable overview of high-throughput, genomics-based technologies and their applications to plant breeding • Each chapter explores a single methodology, allowing for detailed and thorough coverage • Coverage ranges from well-established methodologies, such as genomics and proteomics, to emerging technologies, including phenomics and physionomics Aluízio Borém is a Professor of Plant Breeding at the University of Viçosa in Brazil. Roberto Fritsche-Neto is a Professor of Genetics and Plant Breeding at the University of São Paulo in Brazil.
Applied Biotechnology Strategies to Combat Plant Abiotic Stress investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress in which Although knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies is avaiable, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner. In 32 chapters Applied Biotechnology Strategies to Combat Plant Abiotic Stress focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress namely drought, salt, cold, heat, heavy metals, in major C3 and C4 food crops. Together with this, the book provides updated knowledge of common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches This book is a valuable resource for early researchers, senior academicians, and scientists in the field of biotechnology, biochemistry, molecular biology, researchers in agriculture and, crops for human foods, and all those who wish to broaden their knowledge in the allied field. Describes biotechnological strategies to combat plant abiotic stress Covers the latest evidence based multipronged approaches in understanding omics perspective of stress tolerance Focuses on the integration of multi-OMICS technologies in deciphering molecular intricacies of plant abiotic stress
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.
The recent data flood has required greater and greater reliance on computational usage in plant biology. This Research Topic will focus on the utility of computational approaches across the breadth of modern plant biology with particular focus on the following areas: (i) Comparative genomics- gene family size in the green lineage (ii) Adaptive evolution - specifics of development (iii) Adaptive evolution - specifics of secondary metabolism (iv) Translational biology- co-response analysis from arabidopsis outwards (v) Conserved(and differential) transcriptional response to stress (vi) Transcriptomics databases (vii) Translatomics (ix) Proteomics- abundance (x) Proteomics- location, (xi) Proteomics- interactions (xii) Proteomics databases (xiii) he activome (xiv)Metabolite-abundance (xv) metabolite- location (xvi) Experimental flux calculations, (xvii)dvanced metabolomic technologies (xviii) metabolite databases (xix) Genome wide metabolic modelling
To comprehend the organizational principle of cellular functions at diff erent levels, an integrative approach with large-scale experiments, the so-called ‘omics’ data including genomics, transcriptomics, proteomics, and metabolomics, is needed. Omics aims at the collective characterization and quantifi cation of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms. Currently, omics is an essential tool to understand the molecular systems that underlie various plant functions. Furthermore, in several plant species, the development of omicsresources has progressed to address the particular biological properties of individual species. Integration of knowledge from omics-based research is an emerging issue as researchers seek to identify significance, gain biological insights and promote translational research. From these perspectives, we intend to provide the emerging aspects of plant systems research based on omics and bioinformatics analyses together with their associated resources and technological advances. Th e present book covers a wide range of omics topics, and discusses the latest trends and application area of plant sciences. In this volume, we have highlighted the working solutions as well as open problems and future challenges in plant omics studies. We believe that this book will initiate and introduce readers to state-of-the-art developments and trends in omics-driven research.