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This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice
Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications. Substances covered include military-related chemicals including explosives, propellants, pesticides and metals. Wildlife Toxicity Assessments for Chemicals of Military Concern is a much-needed resource designed to meet the needs of those seeking toxicological information for ecological risk assessment purposes. Each chapter targets a specific chemical and considers the current knowledge of the toxicological impacts of chemicals to terrestrial wildlife including mammalian, avian, amphibian and reptilian species. - Provides detailed information on how Wildlife Toxicity Values (TRVs) for military chemicals of concern are derived and evaluated. - Covers wildlife toxicity assessments of explosives, metals and environmental chemicals. - Compiles relevant information on the environmental effects of chemicals on wildlife in relation to public and environmental health.
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.
Hazardous pollutants are a growing concern in treatment engineering. In the past, biological treatment was mainly used for the removal of bulk organic matter and the nutrients nitrogen and phosphorous. However, relatively recently the issue of hazardous pollutants, which are present at very low concentrations in wastewaters and waters but are very harmful to both ecosystems and humans, is becoming increasingly important. Today, treatment of hazardous pollutants in the water environment becomes a challenge as the water quality standards become stricter. Hazardous Pollutants in Biological Treatment Systems focuses entirely on hazardous pollutants in biological treatment and gives an elaborate insight into their fate and effects during biological treatment of wastewater and water. Currently, in commercial and industrial products and processes, thousands of chemicals are used that reach water. Many of those chemicals are carcinogens, mutagens, endocrine disruptors and toxicants. Therefore, water containing hazardous pollutants should be treated before discharged to the environment or consumed by humans. This book first addresses the characteristics, occurrence and origin of hazardous organic and inorganic pollutants. Then, it concentrates on the fate and effects of these pollutants in biological wastewater and drinking water treatment units. It also provides details about analysis of hazardous pollutants, experimental methodologies, computational tools used to assist experiments, evaluation of experimental data and examination of microbial ecology by molecular microbiology and genetic tools. Hazardous Pollutants in Biological Treatment Systems is an essential resource to the researcher or the practitioner who is already involved with hazardous pollutants and biological processes or intending to do so. The text will also be useful for professionals working in the field of water and wastewater treatment.