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Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods. - Provides updated information about exposure and neurotoxic outcomes - Includes indication on new tools for neurobehavioral assessment - Covers practical indications on preventive aspects
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Dr. Jose A. Valciukas, in Foundations of Environmental and Occupational Neurotoxicology, has written a thorough, lively, and educational study on toxic substances and their effects. Written in a manner that is accessible to both professionals and non-professionals, Dr. Valciukas explains how health and human behavior may be adversely affected by neurotoxins. He introduces his study with a history of environmental and occupational neurotoxicology.
Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.
Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment. The book contains chapters on the most important workplace exposures such as metals, pesticides, solvents, plastics, gases, and particulate matter, as well as the organs likely to be affected. The lungs and the skin are given individual consideration as common sites of injury and disease caused by exposure to chemicals. Genotoxicity and cancer are also singled out for particular attention due to ongoing concern about cancer-related effects of chemicals. Important fields interfacing with occupational toxicology - hygiene, epidemiology, and occupational medicine - are also covered to assist the reader in understanding the necessity of cross-discipline considerations in dealing with workplace exposures. This practical approach makes this book particularly valuable to students of toxicology as well as to occupational health and safety professionals at all levels.
Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment.
Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. - Serves as an all-in-one resource for toxicology information - New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports - Updated to include the latest internet and electronic sources, e-mail addresses, etc. - Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects
Many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses: Neurotoxic agents commonly encountered in the workplace Signs and symptoms of neurotoxicity and of the factors affecting neurotoxic effects Biological monitoring and the use of biomarkers Epidemiological methods and clinical approaches to occupational neurotoxicology The analysis of behavioral, electrophysiological, and imaging techniques in the diagnosis of neurotoxicity Occupational neurotoxicity in developing countries The evaluation and management of occupational illnesses due to neurotoxicity Occupational Neurotoxicology concisely covers important facts on the adverse effects of chemical, biological, and physical agents that can impair or alter the structure of the nervous system. Professionals and researchers in the fields of occupational medicine, toxicology, epidemiology, neurology, industrial hygiene, and psychology will all find relevant information on the health problems that can occur from exposure to neurotoxicants.
Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.