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The Department of Commerce, Economic Development Administration, in conjunction with the National Institute of Standards and Technology, asked the IDA Science and Technology Policy Institute (STPI) to study the landscape of technology transfer and commercialization at the federal laboratories to serve as a baseline for further action. The study began with a literature review that informed the approach to discussions with technology transfer personnel at federal agencies and laboratories. These discussions, the primary mode of data collection, were held with representatives from 13 agencies and subagencies, 26 laboratories, and 33 other organizations. These discussions provided an understanding of technology transfer and commercialization activities at the laboratories, identified perceived barriers to technology transfer, and uncovered strategies with potential for overcoming these barriers. They also revealed factors that affect the speed and dissemination of technologies from the laboratories.