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This book demonstrates that nutrients play a direct role as co-factors and regulators of the immune system. The book also shows that modulating the immune response with nutrients can provide a fundamental approach to preventive medicine.;Containing nearly 2300 bibliographic citations as well as illustrative figures, tables, and micrographs, this book is designed to be of interest to clinical immunologists, immunology and vitamin researchers, nutrition specialists, paediatricians, neonatologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.
This book demonstrates that nutrients play a direct role as co-factors and regulators of the immune system. The book also shows that modulating the immune response with nutrients can provide a fundamental approach to preventive medicine.;Containing nearly 2300 bibliographic citations as well as illustrative figures, tables, and micrographs, this book is designed to be of interest to clinical immunologists, immunology and vitamin researchers, nutrition specialists, paediatricians, neonatologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Nutrition and Immunity discusses the interaction between nutrition, immune function, and immunity, based on empirical and epidemiologic point of view. It is organized into 14 chapters that focus on experimental studies on laboratory animals, including animal models to isolate specific factors in the interaction between nutrition and immunity. The book starts with an introduction to the potential impact of nutritional factors on immune responsiveness. Two chapters deal with the evaluation of immune function and nutritional assessment. Other chapters present classic observations on malnutrition and infectious disease, involving field studies as well as studies on the effect of nutritional factors on immune ontogeny. The following chapters examine issues related to caloric intake, proteins, minerals, vitamins, lipids, breast milk, and alcohol, as well as their effects in immune function and immunity. The book’s final chapters cover future directions and the potential role of nutritional modulation in immune dysfunction. Each chapter is meant to be an authoritative review presenting the state of the art as well as providing key illustrations from classic papers in a given field. Nutritionists, immunologists, scientists, and researchers will find this book very helpful in expanding their knowledge in the interrelationship between nutrition and immunity.
It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.
This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.
Supporting initiation, development and resolution of appropriate immune responses is key to survival. Many nutrients and dietary components have been purported to have a role in supporting optimal immune function. This is vital throughout the life course, from the development and programming of the immune system in early life, to supporting immunity and reducing chronic inflammation in older people. In this special issue of Nutrients, we examine the evidence for the role of diet and dietary components in promoting protective immunity.
Dietary Components and Immune Function focuses on immune modulation, immune mediated disease resistance, immune changes due to AIDS, immune modulated cancer therapy, and autoimmune diseases as modified by dietary supplement, bioactive foods and supplements. The potential value of such approaches in maintaining wellness and preventing disease are addressed by examining their effects in vitro and in vivo on innate and adaptive immune responses. Emerging fields of science and important discoveries relating to early stages of new nutriceuticals in cancer prevention, prior to clinical trials are also covered. This volume represents a single source of material related to nutriceuticals and their constituents as they relate to cancer therapy and prevention. As such the book will be essential reading for nutritionists, pharmacologists, health care professionals, research scientists, cancer workers, pathologists, molecular or cellular biochemists, physicians, general practitioners as well as those interested in diet and nutrition in disease resistance via immune regulation.
This book was written to provide a thorough overview of clinical nutrition and immunology to allow the reader to become knowledgeable in this evolving and complex area of medicine. The reader, whether a clinician, student, teacher, or researcher, will find this book comprehensive and up to date.The disease-specific chapters have been written to focus attention on novel approaches to nutrient-immune system interactions that affect specific diseases. This includes the identification of immunologic actions that can be influenced by nutrition. Specific nutrient chapters were written by experienced investigators to provide the reader with an understanding of the current role of nutrients in the immune system with both clinical and research applications. Throughout the book, the authors actively emphasize new frontiers for research and practical use of new findings in the fields of nutritional medicine and nutritional pharmacology.
Nutrition plays a fundamental role in the maintenance of good health. The link between nutrition and immunity is evident from the effects of malnutrition which results in secondary immunodeficiency, and vitamin and mineral deficiencies which lead to increase in susceptibility to infectious diseases. In recent years, advances in clinical and experimental studies have provided the mechanistic basis of the effects of nutrients on immune cells. This book is aimed at nutrition or dietetics students who are learning immunology for the first time. It covers all related fields comprehensively, from vitamins and minerals to food allergies and probiotics. Special topics such as cancer and exercise are also introduced. It will help establish a good foundation for students to understand how nutrients can affect the function of immune cells and maintain a healthy body in normal and diseased states.