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Nunn's Applied Respiratory Physiology
Nunn's Applied Respiratory Physiology, Seventh Edition covers all aspects of respiratory physiology in health, disease, and altered conditions and environments, from basic science to clinical applications. Includes functional anatomy, mechanics, control of breathing, ventilation, circulation, ventilation-perfusion matching, diffusion, carbon dioxide and oxygen, and non-respiratory functions of the lung. Discusses the effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia on respiratory physiology. Explores specific clinical disorders such as ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury, as well as the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation. Chapter on Parenchymal Lung Disease has been specifically expanded to include the physiology and pathology of the pleural space and lung cancer. Contains a new chapter on Pulmonary Surgery, covering a wide range of surgical interventions from bronchoscopy to lung resection. Includes almost 500 new references to the literature. The result is an invaluable source for those preparing for examinations in anaesthesia and intensive care, as well as an essential purchase for practitioners who want quick reference to current knowledge. Describes respiration in health and disease and in normal and abnormal situations, to help readers manage all conditions they see in their practices. Examines the respiratory effects of exercise, sleep, smoking, anaesthesia, drowning, anaemia, pregnancy, and other events as well as environmental factors such as altitude, flying, high pressure, closed environments, and air pollution on respiration. Maintains the clarity of style and single-author approach of previous editions through the close collaboration of Andrew Lumb and John Nunn. Makes difficult concepts easy to understand and apply with nearly 300 illustrations. A new chapter on the History of Respiratory Physiology. More coverage of pathophysiology and even more applications of respiratory physiology to clinical practice. A more consistent organization, a revised page design that aids readability, and an art program featuring new and newly redrawn illustrations.
This is a text for anaesthetists, physiologists and anyone seeking information about the basic principles and applications of lung function. This edition has been revised to include new scientific findings.
First book devoted to the diagnosis and treatment of sexual pain in women Female Sexual Pain Disorders is a remarkable fusion of clinical and scientific knowledge that will empower women’s healthcare professionals to help their patients in overcoming this common debilitating disorder. Based on the highest level research, it provides state-of-the-art practical guidance that will help you to: Evaluate and distinguish the causes of sexual pain in women Differentiate the many forms of sexual pain Implement multidisciplinary treatments Distilling the experience of world leaders across many clinical, therapeutic and scientific disciplines, with an array of algorithms and diagnostic tools, Female Sexual Pain Disorders is your ideal companion for treating the many millions of women who suffer from this disorder worldwide. All proceeds from this book are being donated to the International Society for the Study of Women’s Sexual Health (ISSWSH).
The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
This easy yet comprehensive reference guide covers the mechanisms of respiratory diseases, explaining the main respiratory conditions for clinicians and postgraduate trainees. It discusses their aetiology as well as the basic concepts required to effectively evaluate and treat them. Applied Respiratory Pathophysiology is the first book to bring together detailed, clinically-relevant explanation of respiratory physiological processes and pathophysiological processes in one text. It is essential reading for anyone diagnosing and treating specific clinical conditions of the lungs.
The Oxford Textbook of Obstetrics and Gynaecology is an objective and readable text that covers the full speciality of obstetrics and gynaecology. This comprehensive and rigorously referenced textbook will be a vital resource in print and online for all practising clinicians. Edited by a team of four leading figures in the field, whose clinical and scientific backgrounds collectively cover the whole spectrum of obstetrics and gynaecology with particular expertise in fetomaternal medicine and obstetrics, gynaecological oncology, urogynaecology, and reproductive medicine, the textbook helps inform and promote evidence-based practice and improve clinical outcomes worldwide across all facets of the discipline. The editors are supported by contributors who are internationally renowned specialists and ensure high quality and global perspective to the work. Larger sections on the Basics in Obstetrics and Gynaecology, Fetomaternal Medicine, Management of Labour, Gynaecological problems, and Gynaecological Oncology are complimented by specialist sections on areas such as Neonatal Care and Neonatal Problems, Reproductive Medicine, and Urogynaecology and Pelvic Floor Disorders to name a few. The evidence-based presentation of diagnostic and therapeutic methods is complemented in the text by numerous treatment algorithms, giving the reader the knowledge and tools needed for effective clinical practice. The Oxford Textbook of Obstetrics and Gynaecology is essential reading for obstetricians and gynaecologists, subspecialists, and trainees across the world.
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
The aim of this book is to identify and shed new light on the main surgical practices involved in acute care and trauma surgery. Adopting an evidence-based approach, a multidisciplinary team of surgeons and intensivists illustrate basic and advanced operative techniques, accompanied by a comprehensive and updated reference collection. Emerging surgical procedures in Acute Care Surgery are also explored step by step with the help of ample illustrations. Further, the book offers an overview of treatment options for acute organ failure, with a focus on peculiar clinical situations that call for special treatment, including: extracorporeal membrane oxygenation (ECMO), circulatory support and urgent liver transplantation. In order to identify the key determinants in decision-making and therapeutic support that can help avoid critical errors, authors not only define and discuss specific surgical techniques, but also present major issues and controversies related to it. In essence, the book can be considered a “What to do guide” that offers easy access to both basic and advanced lifesaving surgical procedures, due in part to text boxes highlighting “Tips, Tricks and Pitfalls” as well as advice on “Complications Management”. Many chapters are enriched by providing clinical case scenarios, an important educational resource including self–assessment questionnaires.
This book offers comprehensive information on modern approaches to vulvar lesions, taking into account recent management recommendations and employing the consensus terminology of the International Society for the Study of Vulvovaginal Disease (ISSVD). Further, it breaks with past misconceptions and myths, and explains in detail the modern approach. The aim is to help clinicians perform the differential diagnosis of vulvar conditions and implement the new recommended treatments. The core chapters of the book are arranged in accordance with lesion presentation: red lesions, white lesions, patches and plaques, papules and nodules, erosions and ulcers, blisters, etc. For each lesion, the multidisciplinary management is fully explained, including clarifications of the role of gynecologists, dermatologists, physical therapists, pain specialists, sex therapists, and others. Clinical case presentations and numerous illustrations of treatment procedures are included, supplemented by informative online videos. A separate chapter is devoted to vulvar pain, which is increasingly becoming recognized as a growing problem. Here, again the past approaches are replaced with new paradigms. All of the authors are acknowledged experts in the field and the editor is a past president of the ISSVD. The book will be of value for all vulvar specialists and a wide range of other clinicians.