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Obesity is a disease of society and economic transition spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual’s health will be negatively affected. Overweight is thus being considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders.This volume provides the most up to date insights into the biology of a complex endocrine organ: the adipose tissue.
Obesity is considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement. This volume provides insights into the biology of a complex endocrine organ: the adipose tissue.
Diabetes is a metabolic disorder of chronic hyperglycemia that causes numerous complications. The International Diabetes Federation and World Health Organization report that approximately 537 million people worldwide have diabetes in 2021, which may increase to 700 million by 2045. Diabetes and its complications significantly lower the quality of life of patients and cause more than 4 million deaths yearly. Diabetes and its complications also increase premature mortality, increasing society's economic burden. Numerous studies reveal that the chronic multisystem injury and dysfunction can be caused by diabetes, including cardiac and cerebral vascular lesions, nephropathy, retinopathy and neuropathy. In addition, diabetes usually co-occurs with other diseases that may have certain risk factors in common. For example, patients with diabetes are more likely to have hypertension, chronic obstructive pulmonary disease, or asthma. However, there is still a lack of knowledge on the relationship between diabetes and other potential comorbidities such as hepatitis infection, hearing impairment and periodontal disease. Furthermore, common risk factors contributing to the pathogenesis of diabetes and comorbidities are far from fully understood. Several comorbidities (e.g., cardiovascular and cerebrovascular diseases) raise the extra chances of death in patients with diabetes, but the association between diabetes and mortality of other diseases, such as endometrial or kidney cancer, is inconsistent. Further research is still needed to reveal the excess mortality associated with diabetic comorbidities.
In clinical practice, all physicians have to deal with patients suffering from chronic kidney disease. Large numbers of these patients suffer from mild conditions, but nevertheless, they deserve special attention because inappropriate management may accelerate kidney function deterioration. On the other side, patients affected by end-stage renal disease require replacement therapies and often represent a challenge for clinicians due to their complex pathophysiology. Therefore, an adequate knowledge of the most important clinical and therapeutic aspects of renal failure is an essential requirement for every doctor, especially if we consider the increasing incidence and prevalence of this condition. The book summarises the most important etiopathogenetic and pathophysiologic aspects of chronic kidney disease and focuses the attention on important emerging topics: nutritional and dietary management, renoprotective interventions, new evidence about pathophysiological mechanisms provided by base research, innovations in pharmacological treatment, and strategies to improve patient’s quality of life. Data are reported in clear and concise language, supported by graphics, tables, and pictures that facilitate the comprehension of all the arguments.
Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures. The vascular alteration plays an active role in regulation of adipose tissue size and functions. Targeting blood vessels in the adipose tissue have demonstrated to be a novel approach for possibly treatment of cancer, obesity and other metabolic diseases. This book provides the most updated information on this type research and discusses future opportunities for therapy..
The Encyclopedia of Meat Sciences, Second Edition, Three Volume Set prepared by an international team of experts, is a reference work that covers all important aspects of meat science from stable to table. Its topics range from muscle physiology, biochemistry (including post mortem biochemistry), and processing procedures to the processes of tenderization and flavor development, various processed meat products, animal production, microbiology and food safety, and carcass composition. It also considers animal welfare, animal genetics, genomics, consumer issues, ethnic meat products, nutrition, the history of each species, cooking procedures, human health and nutrition, and waste management. Fully up-to-date, this important reference work provides an invaluable source of information for both researchers and professional food scientists. It appeals to all those wanting a one-stop guide to the meat sciences. More than 200 articles covering all areas of meat sciences Substantially revised and updated since the previous edition was published in 2004 Full color throughout
Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.