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New Trends in Smart Nanostructured Biomaterials in Health Sciences provides guidance on the design and synthesis of nanostructured smart biomaterials, as well as the resultant therapeutic effects and associated biomedical applications of these novel materials. The book provides readers with a deeper understanding of these novel biomaterials and aids them in making informed decisions when selecting appropriate materials for tissue engineering and cancer therapy applications. It will be of specific interest to materials scientists, biomedical engineers, oncological scientists, tissue engineers and those working in regenerative medicine. Nanostructured smart materials have the special ability to respond to changes in the cell microenvironment, allowing for robust, biocompatible and rapidly adaptable, therapeutic and restorative action against a range of ailments. These materials are thus ideal candidates for use in tissue engineering and cancer therapy due to the varying nature of the cell microenvironment between persons, tissues and cancers. This book covers the design, synthesis, unique properties and application of smart biomaterials in these two key topic areas of tissue engineering and cancer therapeutics. Presents an overview of how smart biomaterials respond to changes in physiological factors and exogeneous stimuli and their impact in modern medicine Provides readers with the basis for designing, processing and characterizing advanced smart biomaterials Guides the reader through the mechanisms of tissue repair and cancer therapeutics by exploring the most relevant features of smart nanostructured materials
Nanoparticle-Based Polymer Composites discusses recent advancements on the synthesis, processing, characterization and applications of this new class of hybrid materials. Chapters cover recycling and lifecycle assessment, with contributions from leading researchers in industry, academics, the government and private research institutes from across the globe. As nanoparticle-based polymer composites are now replacing traditional polymer composites in a broad range of applications such as fuel cells, electronic and biomedical devices, this book presents the latest advancements in the field. Studies have shown that incorporating metal nanoparticles in polymer matrices can improve their mechanical, thermal, electrical and barrier properties. The unique combination of these properties makes this new class of materials suitable for a broad range of different and advanced applications. Features recent advancements on the synthesis, processing and characterization of nanoparticle-based polymer composites Discusses recycling and lifecycle assessment Highly application-orientated, with contributions from leading international researchers in industry, academia, the government and private research institutes
Nanostructured Biomaterials for Regenerative Medicine focuses on the definition of new trends for the design of biomaterials for biomedical applications. It includes the ex novo synthesis as well as technological strategies to manipulate them into appropriate two-dimensional (2D) and three-dimensional (3D) forms, in order to impart all the main physical, chemical, structural and biological properties requested to achieve desired clinical efficacy. This book aims at offering a concise overview of innovative platforms based on nanostructured biomaterials as a function of their chemical nature - established by a consolidated material classification i.e., polymer, ceramics and metals. For each class, emerging bioinspired systems with rapid expansion in the biomedical research area and fabricated via new enabling technologies will be proposed for the use in tissue repair/regeneration and nanomedicine. This book is an essential resource for researchers, academics and professionals interested in the potential of nanostructured biomaterials for regenerative medicine. Classifies materials into three classes for comprehensive discussion Discusses design techniques to create innovative nanostructured biomaterials Looks at enabling technologies and strategies for emerging applications
Nanostructured materials with designed biofunctions have brought about rapid and significant changes in materials science. "Nanostructured Biomaterials" provides up-to-date reviews of different methods for synthesizing new types of such materials and discusses their cutting-edge technological applications. The reviews mainly focus on potential applications of nanostructured materials in biology and the medical sciences. The book is of general interest to a broad audience of graduate students and researchers active in chemistry, materials science, engineering, biology, and physics. Dr. Junbai Li is a professor at the National Center for Nanoscience and Technology and the Institute of Chemistry, Chinese Academy of Sciences, China.
This new edition of Graphene: Important Results and Applications provides a succinct overview of this innovative material, its history and development, applications, future prospects, and challenges. This 2nd edition has been updated and expanded to include all the latest developments. It covers production of graphene and its derivatives, commercial manufacture of graphene, research results and data on its properties, graphene dispersion, chemical modification, and cutting-edge applications. Eleven groups of production methods of graphene and its derivatives are discussed at length, providing how-to-do and what-to-expect analysis and comparison of potential properties of the resultant products. Also included are ideas for new product development and possible improvement of existing products, as is insight into the unique nature of graphene and its types, including morphology and thickness, mechanical properties, electrical conductivity, elastic properties of 2D and 3D structures, and more. Provides an extensive account of the latest research in methods of production of graphene and its derivatives Covers commercial manufacture, research results, property data, and cutting-edge applications Discusses methods of incorporation in graphene products, chemical modifications, and projected future uses
This book provides a critical overview of the advances being made towards overcoming biological barriers through the contribution of nanosciences and nanotechnologies. Overcoming these barriers is of primary importance for solving the problems of many current drugs and vaccines and it is also especially relevant for the commercial exploitation of new therapeutic strategies i.e. gene and cellular therapies. Despite important information that has been covered in recently published books related to nanomedicine (mainly oriented to technologies and applications), there is still an important gap related to the relationship between the chemical properties of nanobiomaterials and their interaction with the biological environment. Thus, this comprehensive new book that is presented with a clear and organised structure dedicated to the different biological barriers relevant for drug delivery applications will focus on (i) mechanistic issues related to the interaction between drug delivery systems and biological barriers and (ii) the analysis of the critical factors determining the efficacy of nanobiomaterials for specific applications. Moreover, this field has become highly multidisciplinary over the last decade, leading to the development of new products, as well as to significant advances from the regulatory point of view. Moreover, this book will also provide an up-to-date view on the clinical relevance of nanomedicine and on its possible impact on global health.
Handbook of Nano-biomaterials for Therapeutics and Diagnostic Applications covers in-depth topics on nano-biomaterials and nano drug delivery systems (biosensors and bioimaging) involving polymer nanocomposites, metal nanocomposites, and other carbon family fibers and proteins. The book covers the current application of tiny machines or nanodevices and their use as early detection systems for life threatening diseases, giving detailed literature on the development of nanodevices, their use as diagnostic tools, and their present trend in the industry and market. In addition, their synthesis, potential applications and future of smart nanodevices in diagnosis of diseases and their use as smart clinical devices is covered. Users will find sections on recent advances in interdisciplinary research on the processing, morphology, structure and properties of nanostructured materials and their applications in drug delivery for various diseases such as cancer, tuberculosis, Alzheimer disease, ophthalmic diseases, and more. Offers a comprehensive coverage of the therapeutics and smart nanodevices as diagnostic tools and their potential clinical applications in biosensing and bioimaging Includes a glimpse into the nano-biomaterials that are essential components in nanomedicines Describes nanodevices in the early diagnosis of the diseases Explains the nano-drug delivery system for the treatment of various diseases, including cancer, tuberculosis, Alzheimer disease, and ophthalmic diseases Encompasses all information, starting from the design of nano-biomaterials to their applications in theranostics
Nanostructured Materials for Biomedical Applications highlights progress, challenges and opportunities in nanomedicine and discusses novel engineering approaches of nanostructured materials that are useful in various biomedical applications. The book provides a comprehensive review of the state-of-the-art in bio-nanotechnology, with an emphasis on diverse biomedical applications, such as in drug delivery, bioimaging, hyperthermia and targeted cancer therapy. Users will find this to be a broad introductory reference for anyone new to the field or those who wish to gain a thorough overview of nanostructured materials in the context of biomedical applications. The breadth of this book will appeal to an interdisciplinary audience, including materials scientists, pharmaceutical scientists and biomedical engineers. Covers a range of nanomaterial types, including metal nanoparticles, luminescent nanoparticles, cubosomes, smart nanostructures, and much more Reviews the diverse applications of nanomaterials in biomedicine, such as in theranostics, biosensing, cancer therapy, drug delivery and tissue engineering Provides a concise, introductory reference for those new to the fields of bionanomaterials and bio-nanotechnology
This book fills the gap between fundamental and applied research in the use of nanomaterials in biomedical applications, covering the most relevant areas, such as the fundamental concepts of the preparation of nanostructures and regulatory requirements for their safe use in biomedical devices. It also critically discusses what has been achieved in the field, and what needs to be urgently addressed and reviews the state-of-the-art medical uses of nanomaterials for treating damaged organs and tissues. Combining the expertise of clinical researchers working in the field of tissue engineering and novel materials, the book explores the main topics regarding the characterization of materials, specific organ-oriented biomaterials and their applications, as well as regulations and safety. Further, it also examines recent advances, difficulties, and clinical requirements in terms of human bone, cornea, heart, skin and the nervous system, allowing readers to gain a clear and comprehensive understanding of current nanomaterial use in biomedical applications and devices, together with the challenges and future trends. This book is a valuable tool for multidisciplinary scientists and experts interested in fundamental concepts and synthetic routes for preparing nanomaterials. It is also of interest to students and researchers involved in cross-disciplinary research in nanomaterials for clinical applications and offers practical insights for clinicians as well as engineers and materials scientists working in nanoengineering.
- The first reference work ever published on nanostructured biomaterials and their applications. - A unique source of in-depth knowledge of recent advances in applications of nanostructured biomaterials. Most up-to-date emerging aspects of nanobiomaterials and their applications in the field of nanotechnology. - Contains 33 state-of-the-art chapters written by over 70 internationally renowned experts from 10 countries. - About 5,000 bibliographic citations and hundreds of illustrations, figures, tables, chemical structures and equations.