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New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research. Compiles up-to-date information on the chemotherapeutics used in the treatment of infective and metabolic disorders Presents advancements in the discovery of new drugs from plants using molecular and nanotechnology tools Examines detailed information on the use of herbals agents in cancer, HIV and other ailments, including diabetes, malaria and neurological disorders
Approx.344 pages
This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.
Phytomedicine has become more important and gained constant improvement today for the betterment of health. Herbal medicine plays a significant role in the development of new drugs, contrary to the modern medicinal systems. For more than a decade, there has been a drastic improvement in phytomedicine across the world. This growth has reached a higher level in development by pharmaceutical industries everywhere. People have drifted toward herbal medication and practices for their food and health care. Therefore, in order to create abundant interest in the research of phytosciences, this book is one of the better reference tools. The bioactive compounds in plants need to be explored to know the scientific value and therapeutic properties of the medicinal plants against many diseases. This book contains chapters that are relevant to the advanced research in herbal medicines and will enlighten readers to the importance of medicinal plants as daily sources of nutrition and cures for diseases. This book highlights the unique features of the plants that have not been studied so far for their therapeutic potential. To prove the efficacy of medicinal plants, they have to be studied, examined, and scientifically verified. Hence, this book will better serve the researchers working under different aspects of phytomedicine. Features * The information provided through scientific validation is useful to study the pharmacological activity of herbals and their administration in the modern era. * The readers can find clear understanding in the research and development of phytopharmaceutical drugs. * The ideas incorporated in each chapter reveal the knowledge gained in studying the biological activities of the compounds present in the plant, which are indeed most worthy for the development of drugs. * The harvesting of new ideology toward modern scientific technologies that are employed in the field of pharmacological research.
Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications Includes a discussion of synergistic effects of formulations and antagonistic drug interactions Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion
Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity. Includes perspectives from academic and industry research Provides information on the safety, regulatory aspects and clinical aspects related to plant-based drugs Introduces developments of new targeted drug delivery systems
Plants have been used to treat disease throughout human history. On a clay slab that dates back approximately five thousand years, the Sumerians recorded medicinal recipes that made use of hundreds of plants, including poppy, henbane, and mandrake. During the Middle Ages, monks commonly grew and prescribed plants such as sage, anise, and mint in their monasteries. And as the market for herbal remedies and natural medicine grows, we continue to search the globe for plants and plant compounds to combat our various ailments. In Phytomedicines, Herbal Drugs, and Poisons, Ben-Erik van Wyk offers a richly illustrated, scientific guide to medicinal and poisonous plants, including those used for their mind-altering effects. Van Wyk covers approximately 350 species—from Aloe vera and Ephedra sinica to Cannabis sativa and Coffea arabica—detailing their botanical, geographical, pharmacological, and toxicological data as well as the chemical structures of the active compounds in each. Readers learn, for example, that Acacia senegal, or gum acacia, is used primarily in Sudan and Ethiopia as a topical ointment to protect the skin and mucosa from bacterial and fungal infections, and that Aconitum napellus, more commonly known as aconite, is used in cough syrups but can be psychedelic when smoked or absorbed through the skin. With 350 full-color photographs featuring the plants and some of their derivative products, Phytomedicines, Herbal Drugs, and Poisons will be an invaluable reference not only for those in the health care field but also for those growing their own medicinal herb gardens, as well as anyone who needs a quick answer to whether a plant is a panacea or a poison.
Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer’s drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease. Based on traditional literature and up-to-date research, various new therapeutically active compounds have been identified from phytoextracts, which could be useful in the treatment of cognitive disorders. Phytomedicine and Alzheimer’s Disease presents information on Mechanistic aspects of neurodegeneration in Alzheimer’s disease and the role of phytochemicals as restorative agents Understanding the complex biochemical aspects of Alzheimer’s disease Pre-clinical approaches to evaluating drugs to target Alzheimer’s disease Assessing alternative approaches to treating Alzheimer’s disease and the role of alternative medicine to delay the symptomatic progression of this disease Epigenetic changes in Alzheimer’s disease and possible therapeutic or dietary interventions This book serves as an excellent resource for scientific investigators, academics, biochemists, botanists, and alternative medicine practitioners who work to advance the role of phytomedicines in treating Alzheimer’s disease.
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics. Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases. Offers comprehensive coverage of drug delivery to treat metabolic diseases Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of metabolic disorders Includes the most recent research on diagnostic methods and treatment strategies using controlled drug delivery systems