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It is my great pleasure to publish New Frontiers in Lifestyle-Related Dis eases, the proceedings of the Showa University International Symposium for Life Sciences, 3rd Annual Meeting, held at Showa University on Sep tember 13, 2006. This symposium was supported, in part, by Grants for the Promotion of the Advancement of Education and Research in Graduate Schools and Ordinary Expenses for Private Schools from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. On behalf of Showa University, I would like to express my deepest thanks to all the authors and editors for their great contribution to the publication of this memorable book that accelerates research activity in lifestyle-related diseases. Akiyoshi Hosoyamada, M.D., Ph.D. President, Showa University Tokyo, Japan September 2007 v Preface The leading cause of death in Western countries and some developing countries is atherosclerotic cardiovascular diseases. Among them, acute myocardial infarction is the most common type of fatal disease, caused by the progression of atherosclerosis characterized by accumulation of choles terol in vascular walls. Development of atherosclerosis is greatly enhanced by major risk factors for cardiovascular diseases such as obesity, hyperlip idemia, diabetes (hyperglycemia), and hypertension. Among those, obesity frequently initiates a metabolic change that subsequently induces hyperlip idemia, diabetes, hypertension, and eventually atherosclerotic cardiovascu lar diseases. Because obesity and its related disorders largely depend on lifestyle factors such as high calorie intake and low physical activity, a series of disorders are termed lifestyle-related diseases.
Dietary fibre research is rapidly evolving and is stimulated by the growing attention for intestinal health which is needed for combating major disorders such as diabetes, cardio-vascular diseases and obesity. Current research also explores relationships between fibres, the immune system and stress. The recently agreed EU and CODEX definitions for dietary fibre - including all polymeric carbohydrates not digested in the small intestine - provide both clarity and new challenges regarding adequate analysis and concerning the requirements for added fibre. Added fibre should have 'a physical effect of benefit to health as demonstrated by generally accepted scientific evidence to competent authorities'. Novel research tools from genomics toolboxes and advanced systems simulating the gastro-intestinal tract, are enabling researchers to obtain insights in the wide range of structure function relationships of different types of dietary fibre. These include the impact of dietary fibre on the gut microbiota and relationships between prebiotics and peptides involved in regulation of satiety and other functions. New technologies steadily increase the range of fibres, with and without anti-oxidants and other beneficial co-passengers, which are available to food processors. Dietary fibre - new frontiers for food and health covers the most up-to-date research available on dietary fibre and will be an indispensable tool for all scientists and technologists involved in research and development in this field.
Hypertension is another name for high blood pressure. It can lead to severe complications and increases the risk of heart disease, stroke, and death. Blood pressure is the force exerted by the blood against the walls of the blood vessels. Comprising more than 1000 pages, this book is a complete guide to the diagnosis and management of hypertension. Divided into 19 sections, the text begins with an introduction to hypertension, its causes, risk factors, and how it presents in different sectors of the population. The next chapters discuss diagnostic methods and echocardiography. The following sections cover hypertension associated with other disorders including heart failure, stroke, renovascular diseases, metabolic syndrome, and many more. Numerous clinical management strategies are discussed in depth, as well as cardio-oncology, nutrition, and ECMO (Extracorporeal Membrane Oxygenation – a procedure that uses a machine to take over the work of the lungs and sometimes, the heart). A complete section is dedicated to paediatric cardiology and hypertension. With an internationally recognised editor and author team, the comprehensive text is highly illustrated with clinical photographs, diagrams and tables. The book also includes full online access. Key points Comprehensive guide to diagnosis and management of hypertension comprising over 1000 pages Internationally recognised editor and author team Highly illustrated with clinical photographs, diagrams and tables Includes full online access to the book
It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of modifiable risk factors associated with the disease has been present from the outset. Thus, the idea of preventing AD is not new, with reference to strategies noted as early as the 1990s. This subfield of AD research has matured in recent years, with the number of modifiable risk factors – the AD preventome – rising from the 7 initially identified to the current 12, with an estimated contribution to dementia cases worldwide of about 40%. This book, the Handbook of Prevention and Alzheimer’s Disease, introduces physicians, scientists, and other stakeholders to this subfield of AD research. It investigates the AD preventome, which will continue to expand as the understanding of new factors and related biomarkers is refined. Optimizing this preventome leads to an improvement in overall brain health, an outcome which reduces the risk of developing AD and improves quality of life. The book goes on to examine other domains of prevention, from vascular risk factors to social engagement and from sleep health to spirituality. If the journey to end AD can be likened to a long and arduous challenge, understanding every possible part of the overall toolkit of approaches for disease prevention and intervention is essential. Together with its companion volume on intervention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: White matter tracts showing sex differences in connectivity in men versus women as a function of increasing body mass index. Reprinted with permission from Rahmani F, Wang Q, McKay NS, Keefe S, Hantler N, Hornbeck R, Wang Y, Hassenstab J, Schindler S, Xiong C, Morris JC, Benzinger TLS, Raji CA. Sex-Specific Patterns of Body Mass Index Relationship with White Matter Connectivity. J Alzheimers Dis. 2022;86(4):1831-1848. doi: 10.3233/JAD-215329. PMID: 35180116; PMCID: PMC9108572.
Trends such as shifting dietary patterns and an increasingly sedentary lifestyle combined with smoking and alcohol consumption are major risk factors for noncommunicable chronic diseases such as obesity, diabetes, cardiovascular diseases such as hypertension and stroke, cancer dental diseases and osteoporosis. This report reviews the scientific evidence on the effects of diet, nutrition and physical activity on chronic diseases and makes recommendations for public health policies and programmes. Issues considered include the macro-economic implications of public health on agriculture and the global supply and demand for fresh and processed foods.
This book constitutes the thoroughly refereed post-conference proceedings of the JSAI-isAI 2015 Workshops LENLS 12, JURISIN 9, AAA 2015, HAT-MASH 2015, TSDAA 2015, ASD-HR 2015, and SKL 2015, held in Kanagawa, Japan, in November 2015. The 39 regular papers presented in this volume were carefully reviewed and selected from 114 submissions. LENLS 12 (Logic and Engineering of Natural Language Semantics) is an annual international workshop on formal semantics and pragmatics and focused on discourse particles; disjunction; truth; copredication; expressive content; categorial grammar; dependent type semantics; sequent calculus; and various aspects of formal pragmatics. JURISIN 9 (Juris-Informatics) is the 9th event in the series. The purpose of this workshop is to discuss fundamental and practical issues such as law, social science, information and intelligent technology, logic and philosophy, including the conventional “AI and law” area. AAA 2015 (Argument for Agreement and Assurance) has the goal of deepening a mutual understanding and exploring a new research field involving researchers/practitioners in formal and informal logic, artificial intelligence, and safety engineering working on agreement and assurance through argument. HAT-MASH 2015 (Healthy Aging Tech Mashup Service, Data and People) provides a forum to discuss important research questions and practical challenges in healthy aging and elderly care support to promote transdisciplinary approaches. TSDAA 2015 (Workshop on Time Series Data Analysis and its Applications) aimes at providing an interdisciplinary forum for discussion of different approaches and techniques of time series data analysis and their implementation in various real life applications. ASD-HR 2015 (Autism Spectrum Disorders Using a Humanoid Robot) presents the studies in the interdisciplinary field of research including both engineering and medical sides. SKL 2015 (Skill Science) discusses the theoretical foundations of skill science as well as practical and engineering issues.
Emphasizes food groups and dietary patterns in multiethnic populations for the prevention and control of NCDs. Features evidence-based interventions, including nutritional counseling tips, for NCDs prevention and management. Discusses impact-based nutritional models from around the world. Provides practical solutions to prevent and control obesity in children and adults.
The Nexus of Practices: connections, constellations, practitioners brings leading theorists of practice together to provide a fresh set of theoretical impulses for the surge of practice-focused studies currently sweeping across the social disciplines. The book addresses key issues facing practice theory, expands practice theory’s conceptual repertoire, and explores new empirical terrain. With each intellectual move, it generates further opportunities for social research. More specifically, the book’s chapters offer new approaches to analysing connections within the nexus of practices, to exploring the dynamics and implications of the constellations that practices form, and to understanding people as practitioners that carry on practices. Topics examined include social change, language, power, affect, reflection, large social phenomena, and connectivity over time and space. Contributors thereby counter claims that practice theory cannot handle large phenomena and that it ignores people. The contributions also develop practice theoretical ideas in dialogue with other forms of social theory and in ways illustrated and informed by empirical cases and examples. The Nexus of Practices will quickly become an important point of reference for future practice-focused research in the social sciences.
Integrating scientific knowledge with today's most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. - Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment. - Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). - Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment. - Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions. - Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics. - Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders. - Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines. - Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals. - Includes contributions from expert international authors, making this a truly global reference to addiction medicine.
Exercise, a healthy diet, stress management, sound sleep: Most practitioners would agree that living well can mitigate the impact of mental disorders. Yet many are unprepared to address lifestyle factors in their care of patients. Lifestyle Psychiatry seeks to instill confidence by collating and analyzing the impressive emerging body of evidence that supports the efficacy of healthy lifestyle practices -- both as the primary intervention and in conjunction with traditional treatments such as psychopharmacology or psychotherapy -- in preventing and managing psychiatric disorders. This volume examines the impact of lifestyle interventions -- from exercise, yoga, and tai chi to mindfulness and meditation, diet and nutrition, and sleep management -- on psychiatric disorders, including depression, anxiety, posttraumatic stress disorder, schizophrenia, and addiction. Readers can readily find data to support the use of specific lifestyle interventions for a patient presenting with a specific disorder. Detailed descriptions of the mechanisms of each lifestyle intervention also prepare practitioners to educate their patients on the specific neurobiological and psychological effects of these interventions to support their recovery. With chapters that focus on developing a robust therapeutic alliance and inspiring patients to assume responsibility for their own well-being, this guide provides a framework for lasting, sustainable lifestyle changes. Additionally, the book discusses the impact of the provider's lifestyle on clinical behavior and the implications of lifestyle medicine and psychiatry for health care systems and population health, offering a broader examination of the important role this new field can play in leading a sophisticated, holistic approach to optimizing wellness.