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Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The third volume of the series covers the following topics: - P2Y12 receptor agonists -Heart failure pharmacotherapy -Vasopressin and the cardiovascular system -Cerebral small vessel disease -Complement blocking therapeutic strategies -New antiplatelet and anticoagulating agents for gastrointestinal treatments
Hypertension is another name for high blood pressure. It can lead to severe complications and increases the risk of heart disease, stroke, and death. Blood pressure is the force exerted by the blood against the walls of the blood vessels. Comprising more than 1000 pages, this book is a complete guide to the diagnosis and management of hypertension. Divided into 19 sections, the text begins with an introduction to hypertension, its causes, risk factors, and how it presents in different sectors of the population. The next chapters discuss diagnostic methods and echocardiography. The following sections cover hypertension associated with other disorders including heart failure, stroke, renovascular diseases, metabolic syndrome, and many more. Numerous clinical management strategies are discussed in depth, as well as cardio-oncology, nutrition, and ECMO (Extracorporeal Membrane Oxygenation – a procedure that uses a machine to take over the work of the lungs and sometimes, the heart). A complete section is dedicated to paediatric cardiology and hypertension. With an internationally recognised editor and author team, the comprehensive text is highly illustrated with clinical photographs, diagrams and tables. The book also includes full online access. Key points Comprehensive guide to diagnosis and management of hypertension comprising over 1000 pages Internationally recognised editor and author team Highly illustrated with clinical photographs, diagrams and tables Includes full online access to the book
Recent years have witnessed an increasing awareness of the importance and relevance of creativity in social and psychological life. This has led to an awakening of research into creativity. The book "New Frontiers in Creativity" deals with themes that have emerged due to the expanding boundaries of research in creativity. These concern primarily new perspectives in regard to creativity, discovering of creativity in new populations and nurturing of creativity in new domains and spheres of action. The book presents four new perspectives concerning creativity. The first is a comprehensive model of creativity (by Kreitler) that does justice to the complexity of creativity in terms of the constitutive components, ranging from cognition through motivation, emotions, personality, psychopathology, behavior and the environment, focusing on the rich variety of variables in each of the components and their interactions. Another perspective focuses on creativity in the study and research of creativity (by Runco) by adopting meta-cognitive powerful tactics in the study and nurturing of creativity. A third new perspective describes the innovative methods and findings in neurophysiology of creativity, particularly in brain studies (by Shemyakina and Nagornova). The set of new perspectives is complemented by a description of the social processes characterizing the spread and maintenance of innovative ideas (by Fokas). The innovation in terms of populations is presented in the discussion of creativity in individuals diagnosed with dyslexia (by Cancer and Antonietti), in the controversial sphere of psychopathology (by Thys) and in the elderly (by Cohen-Shalev). Notably, the creativity of all three populations has been increasingly recognized in recent years. The third part of the book is devoted to creativity in various domains, including painting (by Vardi), psychotherapy (by Buzdugan, Grigore and Dinca), engineering (by Engel), architecture (by Casakin), sports (by Santos, Sampaio and Memmert) and nature (by Edlinger). The book includes 13 chapters, written by internationally known experts from different countries -- Austria, Belgium, Hungary, Italy, Israel, Portugal, Romania, Russia, and USA -- responsible for discoveries in the specific aspect of creativity with which they deal. The different chapters of the book present innovative approaches, based on empirical evidence and innovative methodologies. Thereby they contribute to the setting of the scene for new developments and new applications of creativity in the rapidly changing world that is in increasing need for creativity.
Performedin the cardiac catheterization laboratory is also included in this section. The next section deals with all aspects of cardiac surgery. Surgery for ischemic heart disease, valve surgery, aortic surgery, robotically assisted cardiac surgery, surgery for congenital heart disease and cardiac transplantation are covered by well-known experts. The last section points to expected refinements and future developments in cardiology, such as stem cell therapy, newer thrombolytics, new frontiers in balloon valvotomy and cardiac transplantation and artificial hearts. This book includes more than 300 full coloured images and illustration. It can be used as a reference book in every library, hospitals, medical colleges and research institutions.
New Frontiers of Cardiovascular Screening using Unobtrusive Sensors, AI, and IoT provides insights into real-world problems in cardiovascular disease screening that can be addressed via AI, IoT and wearable based sensing. Non-Communicable Diseases (NCD) are surpassing CDS and emerging as the foremost cause of death. Hence, early screening of CVDs using wearable and other similar sensors is an extremely important global problem to solve. The digital health field is constantly changing, and this book provides a review of recent technology developments, offering unique coverage of processing time series physiological sensor data. The authors have developed this book with graduate and post graduate students in mind, making sure they provide an accessible entry point into the field. This book is particularly useful for engineers and computer scientists who want to build technologies that work in real world scenarios as it provides a practitioner's view/insights /tricks of the trade. Finally, this book helps researchers working on this important problem to quickly ramp up their knowledge and research to the state-of-the-art. - Maps digital health technology to real diseases that are relevant to the medical community - Supported with patient data and case studies - Gives practitioners insights into the real-world implementation of signal conditioning, signal processing and machine learning
Neurocardiovascular diseases and disturbances are a distinguished group of the pathological entities that demand an integrative scientific approach to be studied, treated and finally, cured. Brain-heart and vessels axes can be comprehended as a complex, bidirectional unit of utmost importance for organism survival. Harmonized functioning of this unit through the autonomic nervous system interface can be fatally compromised by stress, infection, systemic diseases, dietary habits, pharmacological and surgical interventions. The scope of this Research Topic is to emphasize the importance of the scientists’ and medical practitioners’ attention to molecular and systemic modes of the brain-heart and vessels functioning and, often underestimated, neurocardiovascular pathology by a patient’s bedside. In the last couple of decades, this research area flourished and contributed to the general knowledge by placing the new milestones neurocardiovascular physiology and pathology. We hope that by this modest contribution we will provide an interesting, practical and innovative update on the novelties in the field of neurocardiovascular research.
First multi-year cumulation covers six years: 1965-70.
We are delighted to present the 2023 Frontiers in Cardiovascular Medicine “Rising Stars” article collection. This collection showcases the high-quality work of internationally recognized researchers in the early stages of their independent careers. All Rising Star researchers were individually nominated by the Chief Editors of the Journal in recognition of their potential to influence the future directions in their respective fields. The work presented here highlights the diversity of research performed across the entire breadth of cardiovascular medicine, including the elucidation of fundamental biology, the development of novel diagnostics or therapeutics, computational modelling approaches, and bioengineering strategies for regeneration.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.