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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
“An outstanding contribution to the study of aging” from a psychiatrist and professor at Harvard Medical School (Publishers Weekly). In an unprecedented series of studies, Harvard Medical School has followed 824 subjects—men and women, some rich, some poor—from their teens to old age. Harvard's George Vaillant now uses these studies—the most complete ever done anywhere in the world—and the subjects' individual histories to illustrate the factors involved in reaching a happy, healthy old age. He explains precisely why some people turn out to be more resilient than others, the complicated effects of marriage and divorce, negative personality changes, and how to live a more fulfilling, satisfying and rewarding life in the later years. He shows why a person's background has less to do with their eventual happiness than the specific lifestyle choices they make. And he offers step-by-step advice about how each of us can change our lifestyles and age successfully. Sure to be debated on talk shows and in living rooms, Vaillant's definitive and inspiring book is the new classic account of how we live and how we can live better. It will receive massive media attention, and with good reason: we have never seen anything like it, and what it has to tell us will make all the difference in the world. “A respected researcher. . . . offers suggestions for successful and happy aging. Highly recommended.” —Library Journal “Astonishing observations. . . . [Aging Well] provides the only available longitudinal assessment of the factors that will permit us to age well.” —New England Journal of Medicine “Perceptive, understanding, and often tinged with delightful humor.” —Booklist
With this important resource, health care leaders from the board room to the point-of-care can learn how to apply the science of safe and best practices from industry to healthcare by changing leadership practices, models of service delivery, and methods of communication.
Introducing theories and concepts essential for human services administration, this book covers organization theory and management, budgeting and financial management, personnel administration and labor relations, laws and regulations, innovation and change, and data administration and information systems. The author explores bioethics and managing "Babies Doe," legal right to refuse treatment, nursing home payments, and more. He applies important general concepts to specific concerns such as organizational structure and service delivery arrangements, internal financial planning, innovations in drug services delivery, and implementing medical information systems.
The Human Services Delivery System
Winner of the Los Angeles Times Book Prize "A panoramic and perfectly magnificent intellectual history of medicine…This is the book that delivers it all." —Sherwin Nuland, author of How We Die Hailed as "a remarkable achievement" (Boston Globe) and as "a triumph: simultaneously entertaining and instructive, witty and thought-provoking…a splendid and thoroughly engrossing book" (Los Angeles Times), Roy Porter's charting of the history of medicine affords us an opportunity as never before to assess its culture and science and its costs and benefits to mankind. Porter explores medicine's evolution against the backdrop of the wider religious, scientific, philosophical, and political beliefs of the culture in which it develops, covering ground from the diseases of the hunter-gatherers to the more recent threats of AIDS and Ebola, from the clearly defined conviction of the Hippocratic oath to the muddy ethical dilemmas of modern-day medicine. Offering up a treasure trove of historical surprises along the way, this book "has instantly become the standard single-volume work in its field" (The Lancet).
The traditional lines of demarcation between service providers and service users are shifting. Professionals in managed service organizations are working to incorporate the voices of service users into their missions and the way they function, and service users, with growing access to knowledge, have taken on the semblances of professional expertise. Additionally, the human services environment has been transformed by administrative imperatives. The drive toward greater efficiency and accountability has weakened the bond between users and providers. Reimagining the Human Service Relationship is informed by the premise that the helping relationship should be seen as developing in the interactive space between those who provide human services and those who receive them. The contributors to this volume redefine the contours, roles, institutional divisions, means, and aims of providing and receiving services in a range of settings, including child welfare, addiction treatment, social enterprise, doctoring, mental health, and palliative care. Though they advocate an experience-near approach, they remain sensitive to the ambiguities and competing rationalities of the service relationship. Taken together, these chapters reimagine the service relationship by making visible the working relevancies of service delivery.
"How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This book is a case history that illuminates the remarkable progression of science."--BOOK JACKET.