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Electron linear accelerators are being used throughout the world in increasing numbers in a variety of important applications. Foremost among these is their role in the treatment of cancer. Commercial uses include non-destructive testing by radiography, food preservation, product sterilization and radiation processing of materials such as plastics and adhesives. Scientific applications include investigations in radiation biology, radiation chemistry, nuclear and elementary particle physics and radiation research. This manual provides authoritative guidance in radiation protection for this important category of radiation sources.
A textbook for a senior or graduate course in medical or health physics. Students are assumed to be familiar with the radiation- producing devices used in radiation oncology. The second volume corrects some errors detected in the 1998 first, and adds discussions of intensity modulated radiation therapy, CT room design, the design of direct shielded doors, and other topics. Annotation copyrighted by Book News Inc., Portland, OR.
Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.
Edited by internationally recognized authorities in the field, this expanded and updated new edition of the bestselling Handbook, containing more than 100 new articles, is aimed at the design and operation of modern particle accelerators. It is intended as a vade mecum for professional engineers and physicists engaged in these subjects. With a collection of more than 2000 equations, 300 illustrations and 500 graphs and tables, here one will find, in addition to the common formulae of previous compilations, hard-to-find, specialized formulae, recipes and material data pooled from the lifetime experience of many of the world''s most able practitioners of the art and science of accelerators.The eight chapters include both theoretical and practical matters as well as an extensive glossary of accelerator types. Chapters on beam dynamics and electromagnetic and nuclear interactions deal with linear and nonlinear single particle and collective effects including spin motion, beam-environment, beam-beam, beam-electron, beam-ion and intrabeam interactions. The impedance concept and related calculations are dealt with at length as are the instabilities associated with the various interactions mentioned. A chapter on operational considerations includes discussions on the assessment and correction of orbit and optics errors, real-time feedbacks, generation of short photon pulses, bunch compression, tuning of normal and superconducting linacs, energy recovery linacs, free electron lasers, cooling, space-charge compensation, brightness of light sources, collider luminosity optimization and collision schemes. Chapters on mechanical and electrical considerations present material data and important aspects of component design including heat transfer and refrigeration. Hardware systems for particle sources, feedback systems, confinement and acceleration (both normal conducting and superconducting) receive detailed treatment in a subsystems chapter, beam measurement techniques and apparatus being treated therein as well. The closing chapter gives data and methods for radiation protection computations as well as much data on radiation damage to various materials and devices.A detailed name and subject index is provided together with reliable references to the literature where the most detailed information available on all subjects treated can be found.
Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.
Understanding of protons and neutrons, or "nucleons"â€"the building blocks of atomic nucleiâ€"has advanced dramatically, both theoretically and experimentally, in the past half century. A central goal of modern nuclear physics is to understand the structure of the proton and neutron directly from the dynamics of their quarks and gluons governed by the theory of their interactions, quantum chromodynamics (QCD), and how nuclear interactions between protons and neutrons emerge from these dynamics. With deeper understanding of the quark-gluon structure of matter, scientists are poised to reach a deeper picture of these building blocks, and atomic nuclei themselves, as collective many-body systems with new emergent behavior. The development of a U.S. domestic electron-ion collider (EIC) facility has the potential to answer questions that are central to completing an understanding of atoms and integral to the agenda of nuclear physics today. This study assesses the merits and significance of the science that could be addressed by an EIC, and its importance to nuclear physics in particular and to the physical sciences in general. It evaluates the significance of the science that would be enabled by the construction of an EIC, its benefits to U.S. leadership in nuclear physics, and the benefits to other fields of science of a U.S.-based EIC.
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.