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This work focuses on the different patterns of cognitive decline that characterize dementias of various etiologies. The effects of various dementing disorders on different domains of neuropsychological functioning are reviewed, such as attention, memory, intelligence, problem-solving, language skills, visual-spatial functioning, sensory-perceptual abilities, and motor skills. Leading researchers in the field of clinical neuropsychology discuss the unique neuropsychological features of specific dementias and how this information in the context of other clinical data about the patient can aid in making a differential diagnosis. Management issues pertaining to each dementing disorder are also discussed in each chapter. Among the dementing conditions covered are Alzheimer's disease, vascular dementias, dementia associated with alcoholism, tumors, AIDS, and toxicometabolic disorders. Chapters are also devoted to cognitive functioning in normal aging and depression. Up-to-date information concerning neuroimaging, psychopharmacological approaches to treatment, and legal issues in dementia is included in this comprehensive volume.
This book describes the latest advances in our psychological understanding of Alzheimer's disease, bringing together the main experts in this field to describe recent developments. It will be valuable for people working in related disciplines, such as neurology, psychiatry and neuroscience researchers, as well as providing an introduction to the field for psychologists.
With the aging of the baby boomers and medical advances that promote longevity, older adults are rapidly becoming the fastest growing segment of the population. As the population ages, so does the incidence of age related disorders. Many predict that 15% - 20% of the baby-boomer generation will develop some form of cognitive decline over the course of their lifetime, with estimates escalating to up to 50% in those achieving advanced age. Although much attention has been directed at Alzheimer’s disease, the most common form of dementia, it is estimated that nearly one third of those cases of cognitive decline result from other neuropathological mechanisms. In fact, many patients diagnosed with Alzheimer’s disease likely have co-morbid disorders that can also influence cognition (i.e., vascular cognitive impairment), suggesting mixed dementias are grossly under diagnosed. The Clinical Handbook on the Neuropsychology of Aging and Dementia is a unique work that provides clinicians with expert guidance and a hands-on approach to neuropsychological practice with older adults. The book will be divided into two sections, the first addressing special considerations for the evaluation of older adults, and the second half focusing on common referral questions likely to be encountered when working with this age group. The authors of the chapters are experts and are recognized by their peers as opinion leaders in their chosen chapter topics. The field of neuropsychology has played a critical role in developing methods for early identification of late life cognitive disorders as well as the differential diagnosis of dementia. Neuropsychological assessment provides valuable clinical information regarding the nature and severity of cognitive symptoms associated with dementia. Each chapter will reinforce the notion that neuropsychological measures provide the clinician with sensitive tools to differentiate normal age-related cognitive decline from disease-associated impairment, aid in differential diagnosis of cognitive dysfunction in older adults, as well as identify cognitive deficits most likely to translate into functional impairments in everyday life.
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Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level. In discussing both the biological aspects of AD as well as the cognitive functions involved, Alzheimer Disease - Neuropsychology and Pharmacology presents a comprehensive picture of the pathology and approaches to diagnosis and treatment. Basic research including animal models, molecular and genetic aspects is also taken into consideration. In part I, the biological correlates of AD are discussed. In part II the neuropsychological aspects such as cognitive impairment, loss of functional autonomy and emergence of neuropsychiatric disturbances of AD are outlined. In part III, strategies for effective treatment and prevention of AD are discussed. This book will be a useful source of information for clinicians as well as researchers in the area of neuropharmacology.
The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field Summarizes the most recent developments in the fields of Alzheimer's disease and dementia Brings together articles from a prominent and international group of contributors Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences
An essential guide to assessing and treating people with dementia syndromes As the number of older adults with dementia continues to skyrocket, every health care professional needs accurate, up-todate knowledge of these conditions, their prevention, and possible treatments. This compact, evidence-based book discusses essential aspects of the diagnosis, assessment, and interventions of Alzheimer's disease and the syndromes of dementia and mild cognitive impairment. It reviews the diagnostic criteria from the National Institute on Aging, Alzheimer's Association, and the DSM-5 and provides a broad range of treatment options, including psychosocial, educational, and lifestyle interventions. Practitioners will especially appreciate the current overview of caregiver interventions. Practitioners and students alike will find the clear information, the tools for assessment, and other resources provided in this volume extremely useful for helping patients and their families cope with dementia.
In 2011, National Institute on Aging and Alzheimer's Association joint task forces released proposed criteria for Alzheimer' disease diagnosis. These proposals included revisions to the nearly 30-year-old NINDS-ADRDA criteria for Alzheimer's diagnosis and added criteria for diagnosis of Mild Cognitive Impairment (MCI) due to Alzheimer's disease. The same year the American Psychiatric Association proposed new criteria for major and minor neurocognitive disorders (the entities previously known as dementia and mild cognitive impairment, respectively). These new criteria reflect the research and clinical advances in identifying mild cognitive impairment and offer new opportunities for prevention, treatment, and management of neurodegenerative conditions. A major focus of this book is on the mild cognitive impairment prodrome of the common dementias. In addition to discussing the most common neurodegenerative conditions, many rare neurodegenerative conditions are highlighted. Most chapters include an autopsy-confirmed case presentation from the authors' files. Following the case presentation, those chapters present current diagnostic criteria, epidemiology, neuropathology/neurophysiology, genetics, neuroimaging studies as relevant, associated clinical features, differential neuropsychological features and possible interventions for each disorder. The pace of change in research and practice in the field of normal cognitive aging and dementia is increasing almost as fast as the median age of the population. The massive baby boom population bubble is currently entering the age of risk for neurodegenerative conditions. Neuropsychologists will play a major role in refining and applying these diagnoses, and in developing, testing, and refining interventions for these diagnoses, and in caring for this population. This book is intended to prepare neuropsychologists and others interested in neuropsychology to serve this fastest growing segment of our population.
Drawing on the most current research, this study is the perfect companion for those who work alongside elderly people with and without dementia. The book explains why changes in cognition, motor skills, and pain are typical for the elderly while describing the most prevalent subtypes of dementia, including Alzheimer's disease, vascular dementia, and frontotemporal dementia. Focusing on the motor skills of hand motor activity and gait, the study also illustrates changes in the various aspects of pain experience, explaining them clearly through the use of neuropathology of the medial and lateral pain systems. Updates concerning compensation and rehabilitation are also included.
"Cerebrovascular and Alzheimer disease often occur together, but are usually studied apart. This book offers a timely integrated approach to both diseases. Beginning with a section on epidemiology and neuropsychology, this volume goes on to discuss and explore the neuropathological and neurophysiological mechanisms of these disorders. This book then develops a novel concept of an Alzheimer disease/vascular dementia spectrum. Sections on neuroimaging, as well as treatments and interventions follow. The editors have succeeded in gathering an impressive group of clinicians and scientists, who are well qualified by their achievements and leadership to make important contributions to this new integrated approach to dementing disorders. This important book should have broad appeal to anyone studying or caring for patients with dementing disorders, as it is comprehensive, yet focused on a unitary, complementary and pragmatic approach"--