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From reviews of the First Edition: "Being a concise introduction to the principles of neruopathology is a goal this book accomplishes admirably." Annals of Neurology; "unquestionably valuable as a reference text" Arch Path Lab Med; "a fine treatise which truly reflects the current knowledge of the discipline with a strong emphasis on morphologic aspects" Brain Pathology; "an excellent current reference work on neuropathology for practitioners in the various clinical and basic neurosciences" Journal of Neuropathology and Experimental Neurology.
Now in its 5th edition, Escourolle & Poirier Manual of Basic Neuropathology continues the tradition of being one of the most respected texts in neuropathology by providing an introduction to the various diseases of the nervous system and their underlying pathology. This thorough, yet concise manual covers the full spectrum of the various categories of neurologic disease, including neoplasia, trauma, vascular disease, and infection, with separate chapters on prion diseases, multiple sclerosis, degenerative disorders, acquired metabolic diseases, hereditary metabolic diseases, congenital malformations, perinatal diseases, skeletal muscle, peripheral nerve, and the pituitary gland. To accurately guide the clinician, the most current techniques in neuropathology are covered in their own chapter at the end of the book. Richly illustrated throughout, with over 700 images of various neuropathogical diagnoses such as tumor, stroke, infection, degeneration, and malformation among others, this new edition of the classic monograph is an easy-to-use manual for any student, researcher, or practitioner seeking basic information on neuropathology. Used for decades in all fields related to the nervous system-including neurology, neurosurgery, psychiatry, neuroradiology, neuroendocrinology, neuropathology, pathology, and neuroscience- Escourolle & Poirier Manual of Basic Neuropathology is regarded at the 'bible' of neuropathology. This new version has been completely rewritten and expanded to include important updates in genetics and molecular biology, reflective of the important neuropathological discoveries in those fields over the past decade.This book is a practical diagnostic tool and necessary reading for anyone encountering pathological conditions of the nervous system.
The second edition of The Neurology of Consciousness is a comprehensive update of this ground-breaking work on human consciousness, the first book in this area to summarize the neuroanatomical and functional underpinnings of consciousness by emphasizing a lesional approach offered by the study of neurological patients. Since the publication of the first edition in 2009, new methodologies have made consciousness much more accessible scientifically, and, in particular, the study of disorders, disruptions, and disturbances of consciousness has added tremendously to our understanding of the biological basis of human consciousness. The publication of a new edition is both critical and timely for continued understanding of the field of consciousness. In this critical and timely update, revised and new contributions by internationally renowned researchers—edited by the leaders in the field of consciousness research—provide a unique and comprehensive focus on human consciousness. The new edition of The Neurobiology of Consciousness will continue to be an indispensable resource for researchers and students working on the cognitive neuroscience of consciousness and related disorders, as well as for neuroscientists, psychologists, psychiatrists, and neurologists contemplating consciousness as one of the philosophical, ethical, sociological, political, and religious questions of our time. - New chapters on the neuroanatomical basis of consciousness and short-term memory, and expanded coverage of comas and neuroethics, including the ethics of brain death - The first comprehensive, authoritative collection to describe disorders of consciousness and how they are used to study and understand the neural correlates of conscious perception in humans. - Includes both revised and new chapters from the top international researchers in the field, including Christof Koch, Marcus Raichle, Nicholas Schiff, Joseph Fins, and Michael Gazzaniga
The United States Congress designated the 1990's as the "Decade of the Brain" in recognition of the importance of neuroscience to the health and well-being of Americans. It has been suggested that as many as 20% of all patients seeking medical treatment have neurologic problems, either as the presenting complaint or as an associated condition complicating the primary illness. To this end, it is important that physicians understand basic neuroscience principles and nervous system diseases. Of course, this text is not encyclopedic but instead is an outline of the knowledge required of all medical students. Interested students can consult numerous texts that provide comprehensive coverage of the field, including Greenfield's Neuropathology and the exhaustive 60 + volume Handbook of Clinical Neurology. The information selected for inclusion in this volume of the Oklahoma Notes series remains true to the goal of the whole series-incorporating only that material vital in both the general clinical practice of medicine and to answer questions on the all-important United States Medical Licensing Examination. Roger A. Brumback Richard W. Leech Acknowledgments This text would not have been possible without a great deal of help and support from a number of individuals. We want to thank all those who assisted in our education in neuroscience and neuropathology including: William M. Landau and Philip R. Dodge of the Washington University School of Medicine, Lowell W. Lapham of the University of Rochester Medical Center, and Ellsworth C.
Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475
Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
At last, a much-needed route map to pediatric neuropathology. Up to now a comprehensive volume covering of pediatric neuropathology simply did not exist. This atlas is thus a unique, all-encompassing reference providing material on the fundamentals of brain disorders of the nervous system that can affect fetuses, infants and young children, as well as the essentials of diagnosis in developmental brain pathology and neuroimaging. Emphasising the characteristic morphology and a concise summary of clinical features, pathogenesis, and genetics, the generously illustrated atlas presents more than 100 disorders. This compilation is a valuable resource for pathologists, pediatric neurologists and neurosurgeons, geneticists, neonatologists, radiologists, and pediatricians.
The present volume deals with specific aspects of neuropathology for forensic and clinical neuropathologists, with particular emphasis on their relevance to everyday practice. Each chapter includes an overview of the literature as well as specific references and features a wealth of figures, graphs, and tables.
Consciousness is one of the most significant scientific problems today. Renewed interest in the nature of consciousness - a phenomenon long considered not to be scientifically explorable, as well as increasingly widespread availability of multimodal functional brain imaging techniques (EEG, ERP, MEG, fMRI and PET), now offer the possibility of detailed, integrated exploration of the neural, behavioral, and computational correlates of consciousness. The present volume aims to confront the latest theoretical insights in the scientific study of human consciousness with the most recent behavioral, neuroimaging, electrophysiological, pharmacological and neuropathological data on brain function in altered states of consciousness such as: brain death, coma, vegetative state, minimally conscious state, locked-in syndrome, dementia, epilepsy, schizophrenia, hysteria, general anesthesia, sleep, hypnosis, and hallucinations. The interest of this is threefold. First, patients with altered states of consciousness continue to represent a major clinical problem in terms of clinical assessment of consciousness and daily management. Second, the exploration of brain function in altered states of consciousness represents a unique lesional approach to the scientific study of consciousness and adds to the worldwide effort to identify the "neural correlate of consciousness". Third, new scientific insights in this field have major ethical and social implications regarding our care for these patients.
This updated second edition provides a practical and succinct overview of basic neuropathology. Key concepts and basic principles are covered and discussed with particular focus on recent advances, classification, and genetics. Practical points are included to detail how to best use the neuropathology service and interpret the results of pathological tests. Neuropathology Simplified aims to aid the development of multidisciplinary teams and help clinical trainees understand recent advances in neuropathological disorders. The book is also relevant to trainee and resident neurologists, pathologists, and neurosurgeons.