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This book offers a comprehensive review of the most common infectious diseases that affect the nervous system. Written by international experts, it provides a guide to clinicians for accurately diagnosing and treating these challenging syndromes. Organized into six sections, the book presents didactic, up-to-date information on the following topics relating to central nervous system (CNS) infections: diagnosis and evaluation of the patient, bacterial, viral, fungal and mycobacterial infections, disorders of the spinal cord, and a myriad of miscellaneous infections. Chapters specifically reflect and look to resolve the common obstacles clinicians face in the field, such as having unknown etiologies on the majority of CNS infections, insensitive and slow microbiological techniques, an increasing number of immunosuppressed individuals with atypical presentations and pathogens, and a lack of standardized diagnostic algorithms. A complex yet accessible addition to the Current Clinical Neurology Series, Neurological Complications of Infectious Diseases invaluably examines a wide range of infections that have neurological complications and sequelae.
Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.
This book provides an in-depth review of knowledge of neurobrucellosis, which remains common despite significant improvements in preventive measures, neuroradiological techniques, and treatment methods. The chapters are organized into five sections, the first three of which address cranial and intracranial brucellosis, spinal brucellosis, and brucellosis of the peripheral portions of the nervous system. The fourth section focuses on laboratory studies in neurobrucellosis, and the closing section is devoted to therapy, encompassing both medical approaches and the surgical procedures used to treat the complications associated with brucellosis involving the spine, brain, and peripheral nerves. Despite the impressive efforts to eradicate the disease, brucellosis still poses a great threat in the Mediterranean Basin, where it originated, as well as in South and Central America, the Caribbean, and Africa. Written and edited by leading international authorities in the field, this comprehensive book will be an ideal up-to-date reference for neurosurgeons, neurologists, and specialists in infectious disease who are seeking either basic or more advanced information on the disease and its diagnosis and treatment.
Offering a comprehensive review of the neuropathology of SARS-CoV-2, Neurological Care and the COVID-19 Pandemic provides up-to-date coverage of the wide array of the pathogen's neurological symptoms and complications. Drs. Ahmad Riad Ramadan and Gamaledin Osman discuss the neuropathology of SARS-CoV-2, its neurological manifestations, and the impact the pandemic has had on the care of patients with pre-existing neurological conditions. The authors also offer an overview of emerging treatments and vaccines, as well as ways healthcare systems have reorganized in order to respond to the pandemic. - Offers a thorough discussion of the impact the virus has had on the care of patients with neurological ailments, accompanied by recommendations on how to care for these patients. - Covers the impact of COVID-19 on patients with cerebrovascular diseases, seizures, demyelinating diseases, neuromuscular disorders, movement disorders, headache disorders, cognitive disorders, and neuro-oncological disorders. - Includes a detailed case study of how one healthcare system hit hard by COVID-19 successfully transformed itself to respond to the challenges imposed by the pandemic. - Consolidates today's available information on this timely topic into a single, convenient resource.
The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac disorders and diseases may often co-occur with, or cause, subsequent neurological disorders. Heart and Neurologic Disease identifies the top cardiac diseases and disorders most likely to have neurological disorders, how they will present, and how they are best treated. It identifies the mechanisms of action explaining why the conditions co-occur, and what clinicians should look for symptom wise, and how risk may be assessed. Coverage includes genetic cardiac disorders, cardiac trauma, surgery, infection, disease, and arrhythmia. - Identifies the top cardiac diseases and disorders most likely to have neurological complications - Specifies how the neurological complication will present and advance and how it should be treated - Discusses the mechanism of action—why the two conditions co-occur - Includes genetic conditions, trauma, surgery, infection, disease, arrythmias, and more - Covers prevention and risk assessment
Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.
Bacterial Infections of the Central Nervous System aims to provide information useful to physicians taking care of patients with bacterial infections in the central nervous system (CNS), which can lead to morbidity and mortality. The increased number of patients suffering from this infection has led to the development of vaccines and antibiotics. Comprised of four chapters, the book explains the general approach to patients with bacterial CNS infection. It also discusses various CNS infection concepts and terms. These include the characteristic neuroimaging appearance of specific bacterial infections, the limitations of neuroimaging, the cerebrospinal fluid analysis, the pathogenesis and pathophysiology of bacterial CNS infections, the developments of specific adjunctive strategies, and the principles of antimicrobial therapy. It also includes discussions on various diseases that target the CNS, such as meningitis, focal CNS infections, neurological complications of endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, and CNS diseases caused by selected infectious agents and toxins. This book will serve as a guide for clinical physicians who have patients suffering from bacterial CNS infection.
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Neurovirology is an interdisciplinary field representing a melding of virology, clinical neuroscience, molecular pathogenesis, diagnostic virology, molecular biology, and immunology. Neuroviral Infections: General Principles and DNA Viruses covers recent developments in the area of neuroviral infections and discusses their role in related fields such as immunology, cell biology, and molecular biology. It offers a complete discussion of the major neuroviral infections caused by DNA viruses, including information on emerging basic principles, neuroviral infections, and future challenges in virology.
Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.