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In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems. The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques. In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones. Following this detailed structural and anatomical description of the neuroendocrine system, the book’s final section focuses on the hypothalamic control of neuroendocrine functions. This includes the control of circadian rhythm, metabolism and appetite via specific peptidergic circuits. This book provides essential information on the neuroanatomy and control of neuroendocrine systems, addresses cutting-edge research questions posed by recent advances in the development of potent neuroanatomical tools, and highlights the latest technologies used in neuroendocrinology research, making it a valuable reference guide for students, trainees and established researchers alike. This is the twelfth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
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The hypothalamus plays a crucial role in the regulation of food intake and energy homeostasis. Hypothalamic neuronal circuits thus represent a privileged target for the treatment of eating disorders and metabolic diseases. The present eBook constitutes a unique collection of research articles and reviews that highlight new concepts and recent findings about the neuroendocrine control of feeding behavior.
This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding the neuroendocrine control of metabolism. Guest edited by Christoph Buettner, the topics covered include leptin signaling, hypothalamic inflammation, hypoglycemia awareness, perinatal programming of metabolic disease, substrates, and more.
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Perspectives on Behavioral Medicine, Volume 2: Neuroendocrine Control and Behavior provides a selective overview of important recent developments in the neurosciences related to neuroendocrine control mechanisms which have important implications for major areas of interest in behavioral medicine. The book begins with a general introductory chapter that presents a synthesis of related developments in the biomedicai and behavioral sciences which have played an important role in the emergence of the field of behavioral medicine, with particular emphasis on developments in behavioral biology concerned with neuroendocrine control. The remaining chapters are organized into two parts. Part I provides an introduction to recent developments concerning neuroendocrine control, as well as a consideration of general implications of such developments for the stress field. Part II shows how the integrative efforts of the first section might be applied toward improving our understanding of the role of behavioral and psychosocial factors in several specific illnesses.
The Neuroendocrine Control of Adaptation examines the mechanisms underlying the neuroendocrine control of adaptation. Topics covered include the anatomical and functional relationships between the adenohypophysis and the adrenal cortex; adrenocortical secretion at rest and under stress; ""specific adaptation"" in pituitary-adrenocortical function; and humoral regulation of the release of the adrenocorticotropic hormone (ACTH). The link between pituitary-adrenocortical and sexual activities with regard to the regulation of the central nervous system is also discussed. This book is comprised of nine chapters and begins with an analysis of the anatomical and functional connections between the adenohypophysis and the adrenal cortex, followed by a review of ACTH secretion at rest and under stress. Subsequent chapters explore humoral regulation of ACTH release; functional connections between the hypothalamus and the adenohypophysis, with emphasis on their role in the regulation of ACTH secretion; the function of the pituitary-adrenocortical system during development; and some physiological and pathological problems concerning the link between higher nervous activity and the pituitary-adrenocortical system. This monograph will be of particular value to physiologists.
Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience. Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels. The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques. The volumes cover of the role of genetics in many endocrine-related events, like neuroendocrinological diseases and endocrine depenedent cancers (prostate, breast, etc,). Interesting information is also provided on possibile treatments of neurodegenerative brain diseases (e.g., Alzheimer and similar syndromes). . The best researchers in the field provide their conclusions in the context of the latest experimental results . Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered . Of great value for researchers and experts, but also for students as a background reference