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Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics. Presents the latest information on placebo studies in clinically relevant models Provides current research and projects on involved brain circuitry and neurotransmitter systems Contains specific chapters on applications
Due to advances within neuroscience, we are now in a much better position to be able to describe and discuss the biological mechanisms that underlie the doctor-patient relationship. Using this knowlege, this book describes and demonstrates the power that the doctor's behaviour has on a patient's behaviour and capacity for recovery from illness.
Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biological process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics. Latest placebo studies in clinically relevant models Current research and projects on the involved brain circuitry and neurotransmitter systems Specific chapters on applications
Psychodynamic psychotherapy and psychoanalysis have had to defend themselves from a barrage of criticisms throughout their history. In this book David Jopling argues that the changes achieved through therapy are really just functions of placebos that rally the mind's native healing powers. It is a bold new work that delivers yet another blow to Freud and his followers.
Based on a meeting in November 2000, this book brings together researchers from a wide range of disciplines to examine the biological, behavioral, social, cultural and ethical aspects related to the placebo effect. Perspectives on the necessity for including a placebo in randomized clinical trials will also be examined. This is the first attempt to examine the evidence-base of the placebo effect and will provide important information for clinicans.
The placebo effect is probably the most striking and well known demonstration of the interaction between psychological and somatic factors. This compendium by leading experts presents the latest findings on this complex psychobiological process. It provides insights into the underlying mechanisms and the neurobiological foundation of the placebo effect and shows how we can now develop principles for clinical application. Specific topics covered include placebo effects on physical performance and influence of verbal suggestions, antidepressant placebo effects, effect of patient involvement in treatment decisions on placebo effects, assessing patient attitudes to and experiences with medication, and transfer of the placebo analgesic effect to anti-itching medication.
Placebo Effects in Neurologic Disease, Volume 153, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Background and Methods in Placebo, Better than Nothing: A Historical Account of Placebos and Placebo Effects from Modern to Contemporary Medicine, Determinants of PE, Strategies for Minimizing PE in Research, Maximizing placebo response in the clinic, Statistical methods for handling PE, Nocebo and Lessebo effects, Ethics of deception, Pain, Parkinson's Disease, Cognitive impairment, Epilepsy, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Neurobiology series Updated release includes the latest information on the placebo effect
A proposal for merging a science of human consciousness with neuroscience and psychology. The study of consciousness has advanced rapidly over the last two decades. And yet there is no clear path to creating models for a direct science of human experience or for integrating its insights with those of neuroscience, psychology, and philosophy. In Inner Experience and Neuroscience, Donald Price and James Barrell show how a science of human experience can be developed through a strategy that integrates experiential paradigms with methods from the natural sciences. They argue that the accuracy and results of both psychology and neuroscience would benefit from an experiential perspective and methods. Price and Barrell describe phenomenologically based methods for scientific research on human experience, as well as their philosophical underpinnings, and relate these to empirical results associated with such phenomena as pain and suffering, emotions, and volition. They argue that the methods of psychophysics are critical for integrating experiential and natural sciences, describe how qualitative and quantitative methods can be merged, and then apply this approach to the phenomena of pain, placebo responses, and background states of consciousness. In the course of their argument, they draw on empirical results that include qualitative studies, quantitative studies, and neuroimaging studies. Finally, they propose that the integration of experiential and natural science can extend efforts to understand such difficult issues as free will and complex negative emotions including jealousy and greed.
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The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain:“This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues. --Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect