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The study of how the brain processes temporal information is becoming one of the most important topics in systems, cellular, computational, and cognitive neuroscience, as well as in the physiological bases of music and language. During the last and current decade, interval timing has been intensively studied in humans and animals using increasingly sophisticated methodological approaches. The present book will bring together the latest information gathered from this exciting area of research, putting special emphasis on the neural underpinnings of time processing in behaving human and non-human primates. Thus, Neurobiology of Interval Timing will integrate for the first time the current knowledge of both animal behavior and human cognition of the passage of time in different behavioral context, including the perception and production of time intervals, as well as rhythmic activities, using different experimental and theoretical frameworks. The book will the composed of chapters written by the leading experts in the fields of psychophysics, functional imaging, system neurophysiology, and musicology. This cutting-edge scientific work will integrate the current knowledge of the neurobiology of timing behavior putting in perspective the current hypothesis of how the brain quantifies the passage of time across a wide variety of critical behaviors.
Timing and Time Perception: Procedures, Measures, and Applications is a one-of-a-kind, collective effort to present the most utilized and known methods on timing and time perception. Specifically, it covers methods and analysis on circadian timing, synchrony perception, reaction/response time, time estimation, and alternative methods for clinical/developmental research. The book includes experimental protocols, programming code, and sample results and the content ranges from very introductory to more advanced so as to cover the needs of both junior and senior researchers. We hope that this will be the first step in future efforts to document experimental methods and analysis both in a theoretical and in a practical manner. Contributors are: Patricia V. Agostino, Rocío Alcalá-Quintana, Fuat Balcı, Karin Bausenhart, Richard Block, Ivana L. Bussi, Carlos S. Caldart, Mariagrazia Capizzi, Xiaoqin Chen, Ángel Correa, Massimiliano Di Luca, Céline Z. Duval, Mark T. Elliott, Dagmar Fraser, David Freestone, Miguel A. García-Pérez, Anne Giersch, Simon Grondin, Nori Jacoby, Florian Klapproth, Franziska Kopp, Maria Kostaki, Laurence Lalanne, Giovanna Mioni, Trevor B. Penney, Patrick E. Poncelet, Patrick Simen, Ryan Stables, Rolf Ulrich, Argiro Vatakis, Dominic Ward, Alan M. Wing, Kieran Yarrow, and Dan Zakay.
Optimized interaction of the brain with environment requires the four-dimensional representation of space-time in the neuronal circuits. Information processing is an important part of this interaction, which is critically dependent on time-dimension. Information processing has played an important role in the evolution of mammals, and has reached a level of critical importance in the lives of primates, particularly the humans. The entanglement of time-dimension with information processing in the brain is not clearly understood at present. Time-dimension in physical world – the environment of an organism – can be represented by the interval of a pendulum swing (the cover page depicts temporal unit with the help of a swinging pendulum). Temporal units in neural processes are represented by regular activities of pacemaker neurons, tonic regular activities of proprioceptors and periodic fluctuations in the excitability of neurons underlying brain oscillations. Moreover, temporal units may be representationally associated with time-bins containing bits of information (see the Editorial), which may be studied to understand the entanglement of time-dimension with neural information processing. The optimized interaction of the brain with environment requires the calibration of neural temporal units. Neural temporal units are calibrated as a result of feedback processes occurring during the interaction of an organism with environment. Understanding the role of time-dimension in the brain information processing requires a multidisciplinary approach, which would include psychophysics, single cell studies and brain recordings. Although this Special Issue has helped us move forward on some fronts, including theoretical understanding of calibration of time-information in neural circuits, and the role of brain oscillations in timing functions and integration of asynchronous sensory information, further advancements are needed by developing correct computational tools to resolve the relationship between dynamic, hierarchical neural oscillatory structures that form during the brain’s interaction with environment.
Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.
The perception of time is crucial for everyday activities from the sleep–wake cycle to playing and appreciating music, verbal communication, to the determination of the value of a particular behavior. With regard to the last point, making decisions is heavily influenced by the duration of the various options, the duration of the expected delays for receiving the options, and the time constraints for making a choice. Recent advances suggest that the brain represents time in a distributed manner and reflects time as a result of temporal changes in network states and/or by the coincidence detection of the phase of different neural populations. Moreover, intrinsic oscillatory properties of neural circuits could determine timed motor responses. This Research Topic, partly an emergence of a Satellite EBBS meeting sponsored by the COST-Action TIMELY, will discuss how time in the physical world is reconstructed, distorted and modified in brain networks by emotion, learning and neuropathology. This Research Topic on Timing contains up-to-date reviews regarding the relationship between time and decision-making with respect to the underlying psychological and physiological mechanisms responsible for anticipation and evaluation processes.
Interdisciplinary perspectives on the feature of conscious life that scaffolds every act of cognition: subjective time. Our awareness of time and temporal properties is a constant feature of conscious life. Subjective temporality structures and guides every aspect of behavior and cognition, distinguishing memory, perception, and anticipation. This milestone volume brings together research on temporality from leading scholars in philosophy, psychology, and neuroscience, defining a new field of interdisciplinary research. The book's thirty chapters include selections from classic texts by William James and Edmund Husserl and new essays setting them in historical context; contemporary philosophical accounts of lived time; and current empirical studies of psychological time. These last chapters, the larger part of the book, cover such topics as the basic psychophysics of psychological time, its neural foundations, its interaction with the body, and its distortion in illness and altered states of consciousness. Contributors Melissa J. Allman, Holly Andersen, Valtteri Arstila, Yan Bao, Dean V. Buonomano, Niko A. Busch, Barry Dainton, Sylvie Droit-Volet, Christine M. Falter, Thomas Fraps, Shaun Gallagher, Alex O. Holcombe, Edmund Husserl, William James, Piotr Jaśkowski, Jeremie Jozefowiez, Ryota Kanai, Allison N. Kurti, Dan Lloyd, Armando Machado, Matthew S. Matell, Warren H. Meck, James Mensch, Bruno Mölder, Catharine Montgomery, Konstantinos Moutoussis, Peter Naish, Valdas Noreika, Sukhvinder S. Obhi, Ruth Ogden, Alan o'Donoghue, Georgios Papadelis, Ian B. Phillips, Ernst Pöppel, John E. R. Staddon, Dale N. Swanton, Rufin VanRullen, Argiro Vatakis, Till M. Wagner, John Wearden, Marc Wittmann, Agnieszka Wykowska, Kielan Yarrow, Bin Yin, Dan Zahavi
Brain-Computer Interface (BCI) sounds comparable to plugging a USB cable into a human brain with a laptop and accessing brain information. However, it is not as simple as it sounds. BCI is a multidisciplinary discipline with an exponential progress parallel to and with Artificial Intelligence for the past decades. Initially started with the Electroencephalography (EEG) analysis, BCI offers practical applications for cortical physiology today. Although BCI outcomes are more perceptible in medicine such as cognitive assessment, neurofeedback, and neuroprosthetic implants, it opens up amazing avenues for the business community through machine learning and robotics. Thought-to-text is one example of a hot topic in BCI. So, it is quite predictable to see BCI for individual usage given the current affordability of platforms for less technologically savvy users as well as BCI integrated within office automation productivity tools. The current trend is towards vulgarization for businesses benefits, by extension to the society at large. Thus, the interest in preparing a book on BCI. This book aims to compile and disseminate the latest research findings and best practices on how BCI is expanding the frontiers of knowledge in clinical practices, on the brain itself, and the underlying technologies.
This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Recent years have seen a remarkable expansion of knowledge about the anatomical organization of the part of the brain known as the basal ganglia, the signal processing that occurs in these structures, and the many relations both to molecular mechanisms and to cognitive functions. This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Organized in four parts - fundamentals, motor functions and working memories, reward mechanisms, and cognitive and memory operations - the chapters present a unique admixture of theory, cognitive psychology, anatomy, and both cellular- and systems- level physiology written by experts in each of these areas. The editors have provided commentaries as a helpful guide to each part. Many new discoveries about the biology of the basal ganglia are summarized, and their impact on the computational role of the forebrain in the planning and control of complex motor behaviors discussed. The various findings point toward an unexpected role for the basal ganglia in the contextual analysis of the environment and in the adaptive use of this information for the planning and execution of intelligent behaviors. Parallels are explored between these findings and new connectionist approaches to difficult control problems in robotics and engineering. Contributors James L. Adams, P. Apicella, Michael Arbib, Dana H. Ballard, Andrew G. Barto, J. Brian Burns, Christopher I. Connolly, Peter F. Dominey, Richard P. Dum, John Gabrieli, M. Garcia-Munoz, Patricia S. Goldman-Rakic, Ann M. Graybiel, P. M. Groves, Mary M. Hayhoe, J. R. Hollerman, George Houghton, James C. Houk, Stephen Jackson, Minoru Kimura, A. B. Kirillov, Rolf Kotter, J. C. Linder, T. Ljungberg, M. S. Manley, M. E. Martone, J. Mirenowicz, C. D. Myre, Jeff Pelz, Nathalie Picard, R. Romo, S. F. Sawyer, E Scarnat, Wolfram Schultz, Peter L. Strick, Charles J. Wilson, Jeff Wickens, Donald J. Woodward, S. J. Young
Understanding temporal integration by the brain is expected to be among the premier topics to unite systems, cellular, computational, and cognitive neuroscience over the next decade. The phenomenon has been studied in humans and animals, yet until now, there has been no publication to successfully bring together the latest information gathered from