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The field of the neurosciences is one of the most rapidly growing in present biological research. Its molecular aspects are dealt with by the discipline of neurobiochemistry. As the theme of the Mosbacher Colloquium, we chose this term rather than the term "neurochemistry", in order to stress the dynamic biochemical aspects of present molecu lar neurobiology and to avoid the flavor of being purely descriptive and "static", which is frequently associated with the term neurochem istry. This appears the more warranted, since the natural products and analytical chemistry phase of discovering the basic chemical com ponents of the nervous system has passed its culmination. The period of assessment has laid the foundation for studying the dynamic inter play of the various chemical components in the actual biological opera tion of nervous tissue. Thus, neurobiochemis~ry is that part of the neurosciences which is dominated by the ways of thinking and the metho dology of biochemistry. For this Colloquium only topics were selected that deal with the biochemistry of neurons. Thus, we excluded from the agenda other neu ral cells such as glial cells (astrocytes, ependymal cells, oligoden drocytes), meningeal cells, and capillary endothelial cells. This restriction was applied for two reasons: (1) The time available for the meeting did not allow an extensive display of the whole spectrum of neurobiochemical research. (2) The biochemistry of neurons is far more advanced than that of any other cell type of the nervous system •.
Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
Thyroid hormone is important for controlling metabolism and many other body functions. Changes in thyroid hormone physiology, its regulation and diseases thereof have been a concern for the mankind. Understanding of the thyroid hormone(s) has been continuously updated and revised. The contributions from different authors have been incorporated in this book for this purpose. The original work of these contributors will be especially useful in furthering the knowledge on thyroid and help in creating new vistas of research.
"Biochemistry Essentials: Formulas Guide" is a concise and indispensable resource that distills the complex field of biochemistry into a user-friendly reference. This book provides a comprehensive collection of essential formulas, equations, and key concepts crucial for understanding the fundamental principles of biochemistry. Designed for students, researchers, and professionals, it serves as a quick and accessible guide to navigate through the core elements of biochemistry, facilitating a deeper comprehension of the molecular processes that underlie life.
Charles Darwin struggled to explain how forty thousand bees working in the dark, seemingly by instinct alone, could organize themselves to construct something as perfect as a honey comb. How do bees accomplish such incredible tasks? Synthesizing the findings of decades of experiments, The Spirit of the Hive presents a comprehensive picture of the genetic and physiological mechanisms underlying the division of labor in honey bee colonies and explains how bees’ complex social behavior has evolved over millions of years. Robert Page, one of the foremost honey bee geneticists in the world, sheds light on how the coordinated activity of hives arises naturally when worker bees respond to stimuli in their environment. The actions they take in turn alter the environment and so change the stimuli for their nestmates. For example, a bee detecting ample stores of pollen in the hive is inhibited from foraging for more, whereas detecting the presence of hungry young larvae will stimulate pollen gathering. Division of labor, Page shows, is an inevitable product of group living, because individual bees vary genetically and physiologically in their sensitivities to stimuli and have different probabilities of encountering and responding to them. A fascinating window into self-organizing regulatory networks of honey bees, The Spirit of the Hive applies genomics, evolution, and behavior to elucidate the details of social structure and advance our understanding of complex adaptive systems in nature.
Because limited training in geriatric psychiatry has tended to give insufficient attention to mental health care for the elderly, clinicians often need help when assessing and treating problems specific to older clients. Clinical Manual of Geriatric Psychiatry provides a single-volume reference that covers the full range of such problems, from depression to dementia. It shows that psychiatrists working with older people must sometimes be willing to play a generalist's role, combining routine medical management with psychiatric interventions or helping with social or situational problems. Drs. Spar and La Rue review the effects of aging on cognitive performance, including clinical presentations of memory loss and medication-induced symptoms of mental disorder. They offer practical guidance to help the clinician not only diagnose and treat these conditions but also address such issues as evaluating competency for informed consent. Enhanced by numerous charts and tables for easy reference, the book boasts a broad range of coverage: • Guidelines to differential diagnosis of depression -- laboratory tests, psychological tests, and symptom rating scales -- along with insights on new directions in psychotherapy, including intervention within primary care. • Assessment of both selective serotonin reuptake inhibitors and non-SSRIs as first-line agents for depression, citing advantages and disadvantages of specific drugs, plus advice on switching or combining antidepressants.• Discussion of the effective use of electroconvulsive therapy -- particularly the use of brief-pulse, bilateral electrode placement -- as well as experimental therapies such as repetitive transcranial magnetic stimulation and vagal nerve stimulation. • Guidance in cognitive mental status examinations and brief screening tools for dementia and Alzheimer's disease, focusing on the Mini-Mental State Exam and summarizing advanced and experimental diagnostics such as single photon emission computed tomography and positron emission tomography. • Appraisal of psychosocial therapies for patients with Alzheimer's Disease, such as behavior modification and reminiscence therapy, plus use of cholinesterase inhibitors for treatment of cognitive deficits.• Review of approaches to anxiety disorders, including differential diagnosis of phobias, generalized anxiety disorder, obsessive-compulsive disorder, and panic disorder, with a focus on psychosocial-behavior therapy and medications of choice. With life expectancies increasing, people over 85 already constitute one of the fastest growing demographics -- and the number of older people with mental disorders is rising as well. Clinical Manual of Geriatric Psychiatry explains how working effectively with older adults requires a blending of specialized knowledge with a flexible approach to the patient -- and shows how to bring that about in daily practice.
International Review of Neurobiology
This proceedings volume presents the latest scientific research and trends in experimental economics, with particular focus on neuroeconomics. Derived from the 2016 Computational Methods in Experimental Economics (CMEE) conference held in Szczecin, Poland, this book features research and analysis of novel computational methods in neuroeconomics. Neuroeconomics is an interdisciplinary field that combines neuroscience, psychology and economics to build a comprehensive theory of decision making. At its core, neuroeconomics analyzes the decision-making process not only in terms of external conditions or psychological aspects, but also from the neuronal point of view by examining the cerebral conditions of decision making. The application of IT enhances the possibilities of conducting such analyses. Such studies are now performed by software that provides interaction among all the participants and possibilities to register their reactions more accurately. This book examines some of these applications and methods. Featuring contributions on both theory and application, this book is of interest to researchers, students, academics and professionals interested in experimental economics, neuroeconomics and behavioral economics.