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Offering extensive information on tardigrades, this volume begins with a chapter on the history of tardigrades, from the first description by Goeze in 1773, until 1929, when the most comprehensive monographic approach by E. Marcus was published. Tardigrades’ organ systems, including their integument, body cavity, digestive, muscular, nervous and reproductive systems, as well as their overall external morphology, are summarized in the second chapter. Subsequent chapters present the current state of knowledge on tardigrade phylogeny, biogeography, paleontology, cytology and cytogenetics. In addition, the book provides insights into the ecology of tardigrades in marine, freshwater and terrestrial habitats. The reproduction, development and life cycles are summarized and the extraordinary environmental adaptations of encystment and cyclomorphosis, desiccation tolerance, freezing tolerance and radiation tolerance are discussed in detail. Further chapters provide an overview of key approaches in molecular tardigrade studies and describe techniques for sampling and sample processing. The book closes with a list of tardigrade taxa up to a sub-generic level, including the type species of each genus, the numbers of lower taxa in each taxon, and the main environments in which the taxa were found. Given its depth of coverage, the volume offers an invaluable resource for scientists from various disciplines who plan to research tardigrades, and for all others who are interested in these fascinating animals.
"This new edition of Merriam-Webster's Rhyming Dictionary contains over 71,000 rhyming words, about 16,000 more than the first edition. The additions naturally include words that have come into common use since the earlier book's publication -- words such as busk, blog, out-there, dreadlocked, fearmonger, and jaw-dropper. But most of the book's additions are not actually new to the language. For the first time, most of the two-, three-, four-, and five-word entries found in Merriam-Webster's Collegiate Dictionary have been given their own place in this volume's lists of rhyming words."--Preface.
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
More than seven years have passed since the first monograph on viroids was published. At that time, the existence of viroids as a novel type of pathogen far smaller than viruses had been amply demonstrated and some of their unusual molecular properties had been elucidated, but the entry of molecular biology into viroid research was still in its infancy. Since that time, our knowledge of the molecular properties of viroids has increased exponentially and viroids have become even more fasci nating than was the case seven years ago. Today, aside from transfer RNA, viroids are probably the best known type of RNA-at least from a struc tural standpoint. Much less is known of the mechanisms of viroid func tion, such as the exact pathway and enzymology of viroid replication and the biochemistry of viroid pathogenesis. Recently, however, emphasis in viroid research has shifted from structural to functional themes and im portant beginnings have been made in the elucidation of viroid struc ture-function relationships. With the discovery of viroidlike RNAs within the capsids of certain plant viruses and the finding of surprising structural similarities between viroids and plant satellite RNAs, the conceptual gap between viroids and conventional viruses has significantly narrowed. Even beyond virology, connecting links with cellular RNAs have come to light and the long isolation of viroids land "viroidologists"J has come to an end.
Webster's Compact Dictionary gives you fast, easy access to the most commonly used words in the English language. In addition to clear, concise definitions, main entries include pronunciations, part-of-speech labels, end-of-the-line hyphenation points, and inflected forms. Provides over 38,000 entries for common words.