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""Natural Products and their Utilization Pattern" presents recent advancements in the field of natural products research. Secondary metabolites such as phenolics, alkaloids, saponins, lipids, carbohydrates and terpenes synthesized by the plants are commercially important leading to the opportunities in the field of drug development in various herbal industries. The book includes 22 chapters with 11 research and 11 review articles, highlighting different dimensions of commercially useful plant based medicines, neutraceuticals, cosmaceuticals, flavor compounds, their ethnobotany and utilization pattern. Some chapters cover nutritive, pharmacological and economical importance of various plant species such as Momordica charantia, Chenopodium album, Curcuma caesia, Rubus ellipticus, Ocimum sanctum, Diploknema butyracea, Meizotropis pellita, Artemisia, Malus domestica, Angelica glauca, Nardostachys jatamansi, Picrorhiza kurroa, Rheum austral, Swertia chirata and Himalayan lichens. The phytochemical screening and antioxidant potential of some wild edible plants and the indirect organogenesis of Nyctanthes arbor-tristis L. for pharmaceuticals and cosmacuticals were also exemplified. Potential of endophytic fungi as a producer of biologically active natural product has been presented as a review article. Other chapters consider the usefulness of natural products for livelihood generation and societal development of the local hill communities. Book also includes phytoremedial aspect of Vinga radiate. nano based medicines in cancer therapy and novel drug delivery applications. This book is extremely useful resource for natural product chemists, biochemists, botanists, biotechnologists, microbiologists, environmentalists, pharmacologists, researchers post graduate students, academicians and industry persons"--
Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design - Includes detailed coverage of therapeutic compound synthesis - Uses multiple real-world examples to support content - Lays out a sustainable template for the future of developing active agents from natural products
With over 1000 original drawings and 500 photographs, this work offers complete coverage of cell biology, plant physiology and molecular biology.
This report is structured in five parts: national framework for traditional and complementary medicine (T&CM); product regulation; practices and practitioners; the challenges faced by countries; and finally the country profiles. Apart from the section on practices and practitioners the report is consistent with the format of the report of the first global survey in order to provide a useful comparison. The section on practices and practitioners which covers providers education and health insurance is a new section incorporated to reflect the emerging trends in T&CM and to gather new information regarding these topics at a national level. All new information received has been incorporated into individual country profiles and data graphs. The report captures the three phases of progress made by Member States; that is before and after the first WHO Traditional Medicine Strategy (1999?2005) from the first global survey to the second global survey (2005?2012) and from the second survey to the most recent timeline (2012?2018).
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
The field of cancer therapeutics faces challenges like limited treatment options, adverse side effects, and drug resistance, leaving a critical gap in addressing this disease. Natural Products as Cancer Therapeutics explores the untapped potential of bioactive compounds derived from nature, providing a fresh perspective on cancer treatment. Authored by esteemed scholars, this book comprehensively examines these compounds and their diverse pharmacological benefits. With cutting-edge research, this book has the potential to revolutionize oncology by expanding treatment options and emphasizing the safety and efficacy of natural compounds. It empowers researchers, practitioners, and scholars to explore new avenues in cancer therapeutics, contributing to improved patient outcomes in the ongoing battle against cancer. Embracing the potential of natural products, this book offers a comprehensive and effective approach to combatting cancer.
This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.
Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.