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Congress requested that the U.S. Department of Homeland Security (DHS) produce a site-specific biosafety and biosecurity risk assessment (SSRA) of the proposed National Bio- and Agro-Defense Facility (NBAF) in Manhattan, Kansas. The laboratory would study dangerous foreign animal diseases-including the highly contagious foot-and-mouth disease (FMD), which affects cattle, pigs, deer, and other cloven-hoofed animals-and diseases deadly to humans that can be transmitted between animals and people. Congress also asked the Research Council to review the validity and adequacy of the document. Until these studies are complete, Congress has withheld funds to build the NBAF. Upon review of the DHS assessment, the National Research Council found "several major shortcomings." Based on the DHS risk assessment, there is nearly a 70 percent chance over the 50-year lifetime of the facility that a release of FMD could result in an infection outside the laboratory, impacting the economy by estimates of $9 billion to $50 billion. The present Research Council report says the risks and costs of a pathogen being accidently released from the facility could be significantly higher. The committee found that the SSRA has many legitimate conclusions, but it was concerned that the assessment does not fully account for how a Biosafety-Level 3 Agriculture and Biosafety-Level 4 Pathogen facility would operate or how pathogens might be accidently released. In particular, the SSRA does not include important operation risks and mitigation issues, such as the risk associated with the daily cleaning of large animal rooms. It also fails to address risks that would likely increase the chances of an FMD leak or of the disease's spread after a leak, including the NBAF's close proximity to the Kansas State University College of Veterinary Medicine clinics and KSU football stadium or personnel moving among KSU facilities.
To safeguard the U.S. against animal disease, research has been conducted at the Plum Island Animal Disease Center (PIADC), off the coast of N.Y., on animal diseases not native to the U.S. PIADC is outdated and too limited to continue as the primary facility for this research. A plan to provide safe, secure, and state-of-the-art agriculture bio-containment labs for R&D of diagnostic capabilities and medical counter-measures for foreign animal and zoonotic diseases has been approved. A new facility will be constructed which would house high-containment labs able to handle the pathogens currently under investigation at PIADC, as well as others. Community concerns about safety and security are being voiced about NBAF. This is a print on demand report.
Safeguarding U.S. agriculture from foreign animal diseases and protecting our food system require cutting-edge research and diagnostic capabilities. The Department of Homeland Security (DHS) and the U.S. Department of Agriculture (USDA) have embarked on an important mission to replace the aging Plum Island Animal Disease Center (PIADC) with a new facility, the National Bio- and Agro-Defense Facility (NBAF). When operational, this new facility would be the world's fourth biosafety level-4 laboratory capable of large animal research. It would serve as a critical world reference laboratory for identifying emerging and unknown disease threats, and would thus be a critical asset in securing the future health, wealth, and security of the nation. DHS selected Manhattan, Kansas, as the site for the new NBAF after an extensive site-selection process that involved an environmental impact statement. The Government Accountability Office (GAO) raised concerns about DHS's analysis of the potential spread of foot-and-mouth disease virus (FMDv), one of the most serious foreign animal disease threats. Congress directed DHS to conduct a site-specific risk assessment (SSRA) for the NBAF, instructed the National Research Council (NRC) to independently evaluate the SSRA, and prohibited obligation of NBAF construction funds until the NRC review was complete. Congress mandated that DHS revise its SSRA to address shortcomings of the 2010 SSRA, directed the NRC to evaluate the updated SSRA (uSSRA), and again prohibited obligation of construction funds until the completion of the second review. The scope for both of these SSRA reports addressed accidental release of pathogens from the NBAF in Manhattan, Kansas and excluded terrorist acts and malicious threats from its risk assessments. Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas is the evaluation of the final uSSRA.
This environmental impact statement presents an evaluation of the DHS proposal to site, construct and operate the NBAF. Operation of the NBAF as a biosafety level-3 (BSL-3) and BSL-4 research facility would allow basic and advanced research, diagnostic testing and validation, countermeasure development, and diagnostic training for addressing high-consequence livestock diseases to U.S. agriculture and public health. Six alternative NBAF sites are evaluated in the DEIS: Athens, Georgia; Manhattan, Kansas; Flora, Mississippi; Plum Island, New York; Butner, North Carolina; and, San Antonio, Texas. The No Action Alternative of not constructing and operating the NBAF is also analyzed.
The agricultural and food infrastructure of the United States may be susceptible to terrorist attack using biological pathogens. In addition to the economic effects of such an attack, some animal pathogens could cause illness in humans. Diseases that can spread from animals to people are known as zoonotic diseases. Scientific and medical research on plant and animal diseases may lead to the discovery and development of new diagnostics and countermeasures, reducing the risk and effects of a successful terrorist attack. To safeguard the United States against the introduction of non-native animal disease, Congress has appropriated funds to the U.S. Department of Agriculture (USDA). Some of this work is performed at the Plum Island Animal Disease Center (PIADC), located off the coast of New York. Congress created the Department of Homeland Security (DHS) in 2003 and transferred ownership and operation of PIADC from USDA to DHS. The USDA and DHS cooperate to conduct foreign animal disease research at PIADC, but they have identified PIADC as outdated and too limited to continue as the primary facility for this research. Homeland Security Presidential Directive 9, issued by President G.W. Bush, tasks the Secretaries of Agriculture and Homeland Security to develop a plan to provide safe, secure, and state-of the art agriculture biocontainment laboratories for research and development of diagnostic capabilities and medical countermeasures for foreign animal and zoonotic diseases. To partially meet these obligations, DHS has requested Congress appropriate funds to construct a new facility, the National Bio- and Agro Defense Facility (NBAF). This facility would house high biocontainment laboratories able to hold the pathogens currently under investigation at PIADC, as well as other pathogens of interest. The DHS has selected Manhattan, Kansas, as the NBAF site and plans to open the facility in 2015. The DHS estimates the final, total facility construction cost as $725 million, significantly exceeding earlier projections. Additional expenses, such as equipping the new facility, relocating existing personnel and programs, and preparing the PIADC facility for disposition, are expected to add $190 million. Research with live foot and mouth disease (FMD) virus is allowed on the U.S. mainland only if explicitly permitted by the USDA Secretary. However, the Food, Conservation, and Energy Act of 2008 (P.L. 110-246) instructs USDA to issue such a permit to DHS for possession of FMD virus at NBAF, subject to select agent rules. The DHS plans regarding the NBAF raise several policy issues. Concerns about safety and security, previously expressed about PIADC and other laboratories being built to study dangerous pathogens, are also being voiced about NBAF. Coordination between DHS and USDA, as well as prioritization and investment in agricultural biodefense, may be reassessed if more high containment laboratory space becomes available.
The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations