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Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. - Describes several electrochemical methods used as detection techniques with biosensors - Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor - Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more
Providing the unique and vital link between the worlds of electrochemistry and nanomaterials, this reference and handbook covers advances in electrochemistry through the nanoscale control of electrode structures, as well as advances in nanotechnology through electrochemical synthesis strategies. It demonstrates how electrochemical methods are of great scientific and commercial interest due to their low cost and high efficiency, and includes the synthesis of nanowires, nanoparticles, nanoporous and layered nanomaterials of various compositions, as well as their applications -- ranging from superior electrode materials to energy storage, biosensors, and electroanalytical devices.
Functionalized Nanomaterial-Based Electrochemical Sensors: Principles, Fabrication Methods, and Applications provides a comprehensive overview of materials, functionalized interfaces, fabrication strategies and application areas. Special attention is given to the remaining challenges and opportunities for commercial realization of functionalized nanomaterial-based electrochemical sensors. An assortment of nanomaterials has been investigated for their incorporation into electrochemical sensors. For example, carbon- based nanomaterials (carbon nanotube, graphene and carbon fiber), noble metals (Au, Ag and Pt), polymers (nafion, polypyrrole) and non-noble metal oxides (Fe2O3, NiO, and Co3O4). The most relevant materials are discussed in the book with an emphasis on their evaluation of their realization in commercial applications. Application areas touched on include the environment, food and medicine industries. Health, safety and regulation considerations are touched on, along with economic and commercialization trends. - Introduces the principles of nanomaterials for electrochemical sensing applications - Reviews the most relevant fabrication strategies for functionalized nanomaterial-based electrochemical sensing platforms - Discusses considerations for the commercial realization of functionalized nanomaterial-based electrochemical sensors in the environment, food and point-of-care applications
Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included. - Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors - Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing - Arranged in a material-by-material way, making it clear how each nanomaterial should be used
Novel Nanostructured Materials for Electrochemical Bio-sensing Applications presents a detailed overview into the fabrication of electrochemical bio-sensing devices. The book addresses the challenges and opportunities relating to sustainable and biocompatible sensors from food, water and wearable applications to the various nanostructured biocompatible materials required for sensor fabrication. In addition, it explores the connection between nanomaterials and sensors and takes into consideration different and novel approaches such as toxic materials monitoring and health issues correlated with the use of nanomaterials. Users will find exciting insight into innovations in nanostructured electrochemical biosensing. By providing its audience with fundamentals, limitations, challenges, future perspectives and practical sustainability, this book will serve as a reference source researchers and engineers within analytical chemistry and electrochemistry. - Showcases the latest progress in new nanostructured materials, bio-sensing types and applications - Provides a comparative vision of electrochemical bio-sensing with other biosensors - Discusses the economics, commercialization, toxicity and life line aspects of electrochemical biosensors
Biosensors Based on Nanomaterials and Nanodevices links interdisciplinary research from leading experts to provide graduate students, academics, researchers, and industry professionals alike with a comprehensive source for key advancements and future trends in nanostructured biosensor development. It describes the concepts, principles, materials, device fabrications, functions, system integrations, and applications of various types of biosensors based on signal transduction mechanisms, including fluorescence, photonic crystal, surface-enhanced Raman scattering, electrochemistry, electro-luminescence, field-effect transistor, and magnetic effect. The book: Explains how to utilize the unique properties of nanomaterials to construct nanostructured biosensors to achieve enhanced performance Features examples of biosensors based on both typical and emerging nanomaterials, such as gold nanoparticles, quantum dots, graphene, graphene oxides, magnetic nanoparticles, carbon nanotubes, inorganic nanowires/nanorods, plasmonic nanostructures, and photonic crystals Demonstrates the broad applications of nanostructured biosensors in environmental monitoring, food safety, industrial quality assurance, and in vitro and in vivo health diagnosis Inspires new ideas for tackling multiscale and multidisciplinary issues in developing high-performance biosensors for complex practical biomedical problems Focusing on the connection between nanomaterials research and biosensor development, Biosensors Based on Nanomaterials and Nanodevices illustrates the exciting possibilities and critical challenges of biosensors based on nanomaterials and nanodevices for future health monitoring, disease diagnosis, therapeutic treatments, and beyond.
Nowadays, the implementation of novel technological platforms in biosensor-based developments is primarily directed to the miniaturization of analytical systems and lowering the limits of detection. Rapid scientific and technological progress enables the application of biosensors for the online detection of minute concentrations of different chemical compounds in a wide selection of matrixes and monitoring extremely low levels of biomarkers even in living organisms and individual cells. This book, including 16 chapters, characterizes the present state of the art and prospective options for micro and nanoscale activities in biosensors construction and applications.
Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. - Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection - Provides application methods and techniques for research analysis for bacteriological detection and food testing - Presents studies using analytical tools to improve food safety and quality analysis
As opposed to conventional electrochemical sensors, nanomaterials-based sensors are active and effective in their action with even a minute concentration of analyte. A number of research studies are bringing about an evolution in their development and advancement because of their unique and effective properties. Nanoscale electrochemical sensors have applications in almost every field of life including the detection of neurochemicals, heavy metals, energy components, body fluids, biological matrices, cancer relevant biomolecules, aromatic hydrocarbons, also in playing their role in food science because of their capability in providing quality control and safety. There is a need to develop these nanomaterials-based electrochemical sensors to be more widely available for accurate sensing of minute concentrations especially in the case of heavy metal detection, biofluids, and other biomaterials. This book outlines the major preparation, fabrication and manufacture of nanomaterials-based electrochemical sensors, as well as detailing their principle medical, environmental and industrial applications in an effort to meet this need.This book is a valuable reference source for materials scientists, engineers, electrochemists, environmental engineers and biomedical engineers who want to understand how nanomaterials-based electrochemical sensors are made, and how they are used. - Explains the techniques used for the fabrication and manufacture of nanomaterials-based electrochemical sensors - Discusses the major applications of nanomaterials-based electrochemical sensors in biomedicine and environmental science - Assesses the potential toxicity and other challenges associated with using nanomaterials-based electrochemical sensors
Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy