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This book provides a critical overview of the advances being made toward overcoming biological barriers through the contribution of nanosciences and nanotechnologies to solve the problems of many current drugs and vaccines.
Nanostructured materials with designed biofunctions have brought about rapid and significant changes in materials science. "Nanostructured Biomaterials" provides up-to-date reviews of different methods for synthesizing new types of such materials and discusses their cutting-edge technological applications. The reviews mainly focus on potential applications of nanostructured materials in biology and the medical sciences. The book is of general interest to a broad audience of graduate students and researchers active in chemistry, materials science, engineering, biology, and physics. Dr. Junbai Li is a professor at the National Center for Nanoscience and Technology and the Institute of Chemistry, Chinese Academy of Sciences, China.
Nanostructured Biomaterials for Regenerative Medicine focuses on the definition of new trends for the design of biomaterials for biomedical applications. It includes the ex novo synthesis as well as technological strategies to manipulate them into appropriate two-dimensional (2D) and three-dimensional (3D) forms, in order to impart all the main physical, chemical, structural and biological properties requested to achieve desired clinical efficacy. This book aims at offering a concise overview of innovative platforms based on nanostructured biomaterials as a function of their chemical nature - established by a consolidated material classification i.e., polymer, ceramics and metals. For each class, emerging bioinspired systems with rapid expansion in the biomedical research area and fabricated via new enabling technologies will be proposed for the use in tissue repair/regeneration and nanomedicine. This book is an essential resource for researchers, academics and professionals interested in the potential of nanostructured biomaterials for regenerative medicine. Classifies materials into three classes for comprehensive discussion Discusses design techniques to create innovative nanostructured biomaterials Looks at enabling technologies and strategies for emerging applications
Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.
- The first reference work ever published on nanostructured biomaterials and their applications. - A unique source of in-depth knowledge of recent advances in applications of nanostructured biomaterials. Most up-to-date emerging aspects of nanobiomaterials and their applications in the field of nanotechnology. - Contains 33 state-of-the-art chapters written by over 70 internationally renowned experts from 10 countries. - About 5,000 bibliographic citations and hundreds of illustrations, figures, tables, chemical structures and equations.
Nanobiomaterials: Nanostructured materials for biomedical applications covers an extensive range of topics related to the processing, characterization, modeling, and biomedical applications of nanostructured ceramics, polymers, metals, composites, self-assembled materials, and macromolecules. Novel approaches for bottom-up and top-down processing of nanostructured biomaterials are highlighted. In addition, innovative techniques for characterizing the in vitro behavior and in vivo behavior of nanostructured biomaterials are considered. Applications of nanostructured biomaterials in dentistry, drug delivery, medical diagnostics, surgery and tissue engineering are examined. Provides a concise description of the materials and technologies used in the development of nanostructured biomaterials Provides industrial researchers with an up-to-date and handy reference on current topics in the field of nanostructured biomaterials Includes an integrated approach that is used to discuss both the biological and engineering aspects of nanostructured biomaterials
This work is a unique source for the rapidly growing biomaterials community on topics at the interface of biomaterials and nanotechnology. The book will cover an extensive range of topics related to the processing, characterization, modeling, and applications of nanostructured medical device materials and biological materials. The book will cover the science and technology of nanostructured ceramics, polymers, metals, and composites, including nanocomposites, self- assembled materials and biological macromolecules. Novel approaches for bottom-up and top-down processing of nanostructured biomaterials will be highlighted. Innovative techniques for characterizing and modeling nanostructured material properties, in vitro behavior, and in vivo behavior will also be included. In addition, applications of nanostructured biomaterials in bioMEMS, cardiology, drug delivery, gene therapy, orthopaedics, ophthalmology, sensing, separation, and tissue engineering will be featured. Finally, topics related to nanostructured material toxicology will be included. The book will serve many groups involved in the development and use of biomaterials, including engineering students, biological science students, and industrial researchers. Provides students and researchers with a concise and structured description of the materials and the technologies used in the development of nanostructured biomaterials, aiding impactful research An integrated approach discusses biological and engineering aspects of nanostructured biomaterials in one place, limiting time wasted in literature review Designed by intent rather than compiled loosely from random articles, the work builds sequential, building-block knowledge with course-suitable pedagogy, bringing researchers rapidly up to speed on any aspect of the are
This book fills the gap between fundamental and applied research in the use of nanomaterials in biomedical applications, covering the most relevant areas, such as the fundamental concepts of the preparation of nanostructures and regulatory requirements for their safe use in biomedical devices. It also critically discusses what has been achieved in the field, and what needs to be urgently addressed and reviews the state-of-the-art medical uses of nanomaterials for treating damaged organs and tissues. Combining the expertise of clinical researchers working in the field of tissue engineering and novel materials, the book explores the main topics regarding the characterization of materials, specific organ-oriented biomaterials and their applications, as well as regulations and safety. Further, it also examines recent advances, difficulties, and clinical requirements in terms of human bone, cornea, heart, skin and the nervous system, allowing readers to gain a clear and comprehensive understanding of current nanomaterial use in biomedical applications and devices, together with the challenges and future trends. This book is a valuable tool for multidisciplinary scientists and experts interested in fundamental concepts and synthetic routes for preparing nanomaterials. It is also of interest to students and researchers involved in cross-disciplinary research in nanomaterials for clinical applications and offers practical insights for clinicians as well as engineers and materials scientists working in nanoengineering.
This book presents recent advances in nanostructured biomaterials. It covers the structures and applications of advanced nanostructured biomaterials. The topics covered include overview on biological activities of thiazole derivatives, imidazole derivatives, pyrazole derivatives, tetrazole derivatives, benzimidazole derivatives, oxazole, isoxazoles, etc. The book also covers the topic of nanocarriers as drug delivery vectors. Given the contents, the book will be useful for students, researchers and professionals working in the area of biomaterials and nanomaterials.