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Measurement of Cardiac Deformations from MRI: Physical and Mathematical Models describes the latest imaging and imag analysis techniques that have been developed at leading centers for the visualization, analysis, and understanding of normal and abnormal cardiac motion with magnetic resonance imaging (MRI). The use of MRI in measuring cardiac motion is particularly important because MRI is non-invasive, and it is the only modality capable of imaging detailed intramural motion within the myocardium. Biomedical engineers, medical physicists, computer scientists, and physicians interested in learning about the latest advances in cardiovascular MRI should find this book to be a valuable educational resource. In particular, it is more tutorial in nature than most of the technical papers where the research was originally published. Practitioners and researchers working in the field of cardiovascular MRI will find the book to be filled with practical technical details and references to other work, enabling the implementation of existing methods and serving as a basis for further research in the area.
Based on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.
This issue of Heart Failure Clinics, guest edited by Dr. Subha V. Raman, will cover key topics in Cardiovascular Magnetic Resonance. This issue is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: When to use CMR for patients with heart failure; Quantifying cardiac dysfunction with CMR; CMR in heritable cardiomyopathies; CMR in ischemic cardiomyopathy; CMR in right heart and pulmonary circulation disorders; CMR of myocardial fibrosis, edema, and infiltrates in heart failure; Magnetic resonance-based characterization of myocardial architecture; CMR in valvular heart disease-related heart failure; Pericardial disease with CMR; CMR's central role in chemotherapy-induced cardiotoxicity; Intracardiac and vascular hemodynamics with CMR in heart failure; Myocardial energetics with CMR; CMR in congenital heart disease: focus on heart failure; and Machine learning in CMR applied to heart failure.
Cardiovascular Magnetic Resonance provides you with up-to-date clinical applications of cardiovascular MRI for the broad spectrum of cardiovascular diseases, including ischemic, myopathic, valvular, and congenital heart diseases, as well as great vessel and peripheral vascular disease. Editors Warren J. Manning and Dudley J. Pennell and their team of international contributors cover everything from basic MR physics to sequence design, flow quantification and spectroscopy to structural anatomy and pathology. Learn the appropriate role for CMR in a variety of clinical settings with reference to other modalities, practical limitations, and costs. With the latest information on contrast agents, MR angiography, MR spectroscopy, imaging protocols, and more, this book is essential for both the beginner and expert CMR practitioner. Covers both the technical and clinical aspects of CMR to serve as a comprehensive reference. Demonstrates the full spectrum of the application of cardiac MR from ischemic heart disease to valvular, myopathic, pericardial, aortic, and congenital heart disease. Includes coverage of normal anatomy, orientation, and function to provide you with baseline values. Discusses advanced techniques, such as interventional MR, to include essential information relevant to the specialist. Features appendices with acronyms and CMR terminology used by equipment vendors that serve as an introduction to the field. Uses consistent terminology and abbreviations throughout the text for clarity and easy reference. Covers both the technical and clinical aspects of CMR to serve as a comprehensive reference. Demonstrates the full spectrum of the application of cardiac MR from ischemic heart disease to valvular, myopathic, pericardial, aortic, and congenital heart disease. Includes coverage of normal anatomy, orientation, and function to provide you with baseline values. Discusses advanced techniques, such as interventional MR, to include essential information relevant to the specialist. Features appendices with acronyms and CMR terminology used by equipment vendors that serve as an introduction to the field. Uses consistent terminology and abbreviations throughout the text for clarity and easy reference.
Although improved treatments have reduced the rates of acute complications from myocardial infarction, sequelae such as heart failure and sudden death threaten the future wellbeing of those patients. Secondary prevention after myocardial infarction is related to cardiovascular risk factors and the effect of the infarct on left ventricular function. Cardiovascular magnetic resonance imaging (CMR) is necessary to determine the size of the infarct scar and can with great precision determine left ventricular volumes, left ventricular ejection fraction, and deformation (strain and torsion). The purpose of this thesis was to improve on CMR methods to facilitate image acquisition and post processing in patients with high risk of coronary artery disease (CAD). In Paper 1, a three-dimensional phase-sensitive inversion-recovery (3D PSIR) sequence was modified to measure T1 during a single breath hold. The measured T1 values were used to extrapolate a map of T1 relaxation, which avoided the time-consuming manual determination of the inversion time. The data collection consisted of phantom experiments, Monte Carlo simulations of the effect of various heart rates, and clinical investigation of 18 patients with myocardial infarction. Scar images created with the modified sequence were compared to those created with the standard sequence. The 3D PSIR sequence was able to measure T1 relaxation with a high accuracy up to 800 ms, which is in the suitable range for scar imaging. Simulated arrhythmias showed that the method was robust and able to tolerate some variation in heart rate. The modified sequence provides measurements of inversion time that can be used to facilitate standard scar imaging or to reconstruct synthetic scar images. Images of infarct scar obtained with the 3D PSIR sequence bore striking similarity to images obtained with the standard sequence. In Paper 2, 125 patients with high risk of CAD were investigated using the displacement encoding with stimulated echoes (DENSE) sequence. Image segments with infarct scar area >50% (transmurality) could be identified with a sensitivity of 95% and a specificity of 80% based on circumferential strain calculated from the DENSE measurements. The DENSE sequence was also applied in other directions, but its sensitivity and specificity to detect scar was lower than when used for circumferential strain. In Paper 3, 90 patients with high risk of CAD were examined by DENSE, tagging with harmonic phase (HARP) imaging and cine imaging with feature tracking (FT), to detect cardiac abnormalities as manifested in end-systolic circumferential strain. Circumferential strain calculated with DENSE had higher sensitivity and specificity than the competing methods to detect infarction with transmurality >50%. Global circumferential strain measured by DENSE correlated better with global parameters such as left ventricular ejection fraction, myocardial wall mass, left ventricular end-diastolic and end-systolic volume; than strain measured by FT or HARP. In Paper 4, myocardial torsion was investigated using DENSE, HARP, and FT in 48 patients with high risk of CAD. Torsion measured by each of the three methods was correlated with other global measures such as left ventricular ejection fraction, left ventricular mass, and left ventricular end-diastolic and end-systolic volumes. The torsion measurements obtained with DENSE had a stronger relationship with left ventricular ejection fraction, left ventricular mass, and volumes than those obtained with HARP or FT. DENSE was superior to the other methods for strain and torsion measurement and can be used to describe myocardial deformation quantitatively and objectively.
Myocardial Torsion is a book different from others, simply because this book is unique, unusual, and I dare say with admiration, it is a curious book, partly magical, full of personality, for initiatory readers, revealing, provocative, challenging. The book has the infrequent peculiarity of being based, to a great extent, on original personal and multidisciplinary investigations, granting it an important extra value. The authors define their purpose since the firsts pages of the book: to provide solidity, validity and even more to Torrent Guasp's concepts. This is certainly a different book in its structure, content and elaboration. It is a text that the reader may admire or criticize, that may create skepticism or surprise at the new data it propose, but wich undoudtedly will leavenobody indifferent, and that is something few books can achieve.
A definitive resource, The ESC Textbook of Cardiovascular Imaging, second edition provides extensive coverage of all cardiovascular imaging modalities. Produced in collaboration with the European Association of Cardiovascular Imaging with contributions from specialists across the globe and edited by a distinguished team of experts, it is a 'state of the art' clinically-orientated imaging reference. Now fully revised and updated with the latest imaging techniques and technology and covering even more conditions than before, it not only discusses the principles of individual modalities but also clearly demonstrates the added value each technique can bring to the treatment of all cardiac diseases. Richly illustrated with colour figures, images, and tables and using a wealth of newly available evidence to link theory to practice, it demonstrates how these techniques can be used in the diagnosis of a range of cardiovascular diseases. Learning how to apply them in practice is made easy with free access to videos and imaging loops online along with the full text so that it is always available, even when on the move. Impressive in scope, The ESC Textbook of Cardiovascular Imaging contains information on cutting-edge technical developments in echocardiography, CT, CMR and hybrid imaging and well imaging's current role in cardiac interventions, such as identifying cardiac structures, helping to guide procedures and exclude possible complications. The application of imaging modalities in conditions such as valvular and coronary heart disease, heart failure, cardiomyopathies, peri-myocardioal disease, adult congenital heart disease and aortic disease, is also extensively considered. From discussion on improved imaging techniques and advances in technology, to guidance and explanation of key practices and theories, this new edition of The ESC Textbook of Cardiovascular Imaging is the ideal reference guide for cardiologists and radiologists alike.
This highly comprehensive and informed textbook has been prepared by the Cardiovascular Magnetic Resonance section of the European Society of Cardiology association on imaging, the EACVI. The EACVI Textbook of Cardiovascular Magnetic Resonance is the authority on the subject. The textbook is aligned with ESC Core Curriculum and EACVI Core Syllabus for CMR. It is a practical resource and provides a disease orientated outlook on the subject. Structured with thirteen clear and detailed sections, ranging from Physics to Methodology, and featuring specific sections on ischemic heart disease, myocardial disease, pericardial disease, and congenital heart disease and adult congenital heart disease, The EACVI Textbook of Cardiovascular Magnetic Resonance provides extensive knowledge across the entire subject area in CMR. Beautifully illustrated and physical principles enriched with schematic animations, the textbook is advanced further with key video content based on clinical cases. Written by leading experts in the field from across the world, the textbook aims to summarise the existing research and clinical evidence for the various CMR indications and provide an invaluable resource for cardiologists and radiologists across the board. The textbook is ideal for cardiologists and radiologists new to the field of Cardiovascular Magnetic Resonance, those preparing for ESC certification in CMR, and those established in the field wishing to gain a deep understanding of CMR. Online access to the digital version is included with purchase of the print book, with accompanying videos referenced within the text available on Oxford Medicine Online.
Based on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.