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A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.; Supports further investigation by summarizing state of the art in the field of Buruli ulcer research Enriches understanding of epidemiology of Buruli ulcer in different geographic regions Reviews exhaustively the characteristics of Mycobacterium ulcerans disease This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Mycobacterium ulcerans disease, also known as Buruli ulcer, is an infection caused by the Mycobacterium ulcerans bacteria. This species of bacteria is found in various aquatic environments, predominantly in areas with a humid and hot climate. It can infect humans and some other animals such as rats and cattle, causing the development of painless open wounds. Myobacterium ulcerans disease affects the skin and bones. It can lead to permanent disfiguration and long-term disability. It does not spread from one person to another. This book includes some of the vital pieces of work being conducted across the world, on the Mycobacterium ulcerans disease, and its diagnosis and treatment. The various studies that are constantly contributing towards advancement in this field are examined in detail. This book will help the readers in keeping pace with the rapid changes in this field.
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
This well-illustrated book is a comprehensive guide to the cutaneous clinical presentations of mycobacterial infections. The Mycobacterium genus includes over 170 species, nontuberculous mycobacteria (NTM) having been added to the obligate human pathogens such as M. tuberculosis and M. leprae. NTM are widely distributed in the environment with high isolation rates worldwide; the skin is a major target with variable clinical manifestations. A current resurgence in tuberculosis is aggravated by the synergy with human immunodeficiency virus, the breakdown of health care systems, and the rise in multidrug-resistant disease, as the incidence of leprosy remains stable, at around 250,000 new cases annually, regardless of effective antibiotic therapy. Presentations of various cutaneous infections caused by mycobacteria may be overlooked by clinicians owing the lack of familiarity with tuberculosis, leprosy, and the related NTM clinical features. This handy guide will help the dermatologist to spot the different clinical manifestations, make a prompt diagnosis, and apply effective treatment.
A highly disabling infectious disease in developing countries, leprosy, or Hansen’s disease, is caused by Mycobacterium leprae, and is still very relevant for the human community due to its transmissible nature, variable presentation and composite clinical picture. Early identification of leprosy and Buruli ulcer (also caused by a Mycobacterium, M. ulcerans) is critical to prevent spreading and patient disability and to establish appropriate therapy. This richly illustrated, completely revised second edition of Leprosy and Buruli Ulcer describes the characteristic signs of both these diseases, and contents include abnormalities of the skin, nerves, eyes, hands, feet, testes and bone. It also presents the latest diagnostic tools to identify and quantify organ damage to enable readers to recognize and treat this composite systemic disorder, which can represent a true medical emergency if affecting eyes, nerves, and kidneys. Further, it includes additional chapters on leprosy in childhood, prophylaxis and vaccines. For both leprosy and Buruli ulcer, this handy guide helps practitioners and nursing personnel to spot the different clinical manifestations, make a prompt diagnosis and apply effective treatment of both these diseases.
This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.
This book is a printed edition of the Special Issue Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge that was published in TropicalMed
Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on Infection problems in systemic autoimmune diseases Provides a practical guide to the safer treatment of infections in patients with autoimmune diseases Includes a number of problems and recommendation that cannot be found in other books Designed as a 'guide to clinical practice' for management and risk interventions required by patients with SAD's