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This book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists.
The common cold is unlike any other human disease because of two f- tors: firstly, it is arguably the most common human disease and, secondly, it is one of the most complex diseases because of the number of viruses that cause the familiar syndrome of sneezing, sore throat, runny nose and nasal congestion. These two factors have made a ‘cure’ for the common cold one of the most difficult scientific and clinical endeavours (a topic often d- cussed in the popular media, where comparisons are made with the ease of putting a man on the moon). The present book brings together a wide range of experts from epidemiologists to virologists and pharmacologists to look at recent advances in our knowledge of the common cold. In some respects the book is unique, as it focuses on the common cold, a syndrome so familiar to the layperson but one that receives little attention from the scientist and clinician. The common cold can be viewed from many different aspects as illustrated in Figure 1. The core knowledge for understanding the common cold must first come from virology and this is discussed in several chapters of the book. There have been major advances in this field because of the use of new methods of detecting viruses such as polymerase chain reaction techniques that have greatly aided our understanding of the epidemiology of viruses associated with common cold.
In the last few years, a significant increase in applications of MMCs has taken place, particularly in the areas of automotive, aerospace, electronics, and recreation. These include continuous fiber reinforced MMCs for cables in power transmission, high temperature superconducting wires, particulate MMCs in civilian aircraft and automotive applications, and high volume fraction, high thermal conductivity substrates for electronic packaging. Nevertheless, as with any novel material systems, there is a lack of fundamental understanding on the part of practicing engineers and designers. This book would seek to address these issues, in a thorough and cohesive manner, as well as to provide students and scientists with a basic understanding of MMCs. This book will emphasize the synergistic relationships among processing, structure, and properties of metal matrix composites.
Cold Wars tells the story of the common cold, the most widespread disease of all. From ancient Egypt to the space age, colds have plagued mankind, and many attempts have been made to find a cure. Today, we spend millions of pounds on remedies and businesses lose millions of pounds through employee sickness- but are we any closer to conquering the cold? In the aftermath of the Second World War, a concerted effort was made in the UK to resolve the scientific conundrum of the common cold. A Common Cold Unit was established near Salisbury, making use of some rather primitive facilities provided by the American Red Cross, and for nearly 50 years was part of the British medical establishment. Much of the research was done on volunteers, who came in large numbers to the CCU to spend days in isolation while scientists attempted to give them a cold. Many eminent scientists, including James Lovelock, were part of the attempt to understand the common cold. This book begins with a brief history of colds through the centuries, describing what earlier generations believed and the strange treatments they tried. That the cold was caused by a virus was only uncovered at the beginning of the last century. The authors vividly describe the establishment of the Common Cold Unit, and its work in uncovering the causes and transmission of the cold and analysing possible treatments. Finally, they assess the progress made in recent years in understanding the psychological aspects of colds, and the latest research on prevention and cures. Cold Wars offers a fascinating account of an eccentric, but effective, attempt to unravel the mysteries of the common cold.
The book explores the clinical challenge of long-term eating disorders and examines the physical and psychological problems, family issues and difficulties in day-to-day living that patients with SEED can experience. Explores the clinical challenge of long-term eating disorders—often compounded by co-morbidity with depression, self-harm, OCD or psychosis Eating disorders can persist for many years, yet are rarely classified as ‘severe and enduring’ in the way that other disorders such as schizophrenia can be Introduces Severe and Enduring Eating Disorder (SEED) as a concept, and draws on detailed case histories to describe its assessment and treatment Examines the physical and psychological problems, family issues and difficulties in day-to-day living that patients with SEED can experience Discusses treatment approaches including Rehabilitation Eating Disorders Psychiatry—also covers treatment in a range of different settings
The contributions to this volume in the African Theatre series make clear that the role of women in the theatre across the continent has changed as control is mainly held by literate elites and women's traditional standing has been lost to men.
This volume hopes to act as a catalyst for some new and exciting areas of enquiry in the more “liminal” interstices of Irish Studies, Traveller Studies, Romani Studies and Diaspora and Migration Studies. These disciplines are all relatively new areas of enquiry in modern Ireland, a country whose society has witnessed very rapid and wide-ranging cultural and demographic change within the short space of a decade. The issue of multiculturalism is not one which is particularly new to Irish society as a number of contributors to this volume point out. What is new however is an increased acknowledgement of diversity and multiculturalism in Ireland and Europe as a whole. Such an acknowledgement makes increased dialogue between “mainstream” society, older minorities such as the Irish Travellers and the many newer immigrant communities such as the Roma all the more necessary. For such constructive dialogue to take place it is vital that migratory peoples and their particular expressions of postcolonial identity be voiced and valued. These identities are both complex and diverse and frequently straddle a number of countries and national identities. It is hoped that this volume will go some way towards the cultivation of such dialogue.