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Pain is a major health concern and a growing field of research. Molecular biologists have made rapid progress in finding relationships between genetics and pain, and Molecular Pain is the first book specifically written to bring this research to doctors and pain scientists. Unlike traditional textbooks, this book utilizes basic neuroscience to explain the mechanisms of pain. It explores current pain medicine as well as alternative treatments for chronic pain, such as acupuncture. Edited by a leading neuroscientist and written by international experts, Molecular Pain is a concise and comprehensive review of recent progress in the field of pain.
This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.
Topic Editor John Streicher is a co-founder and equity partner of Teleport Pharmaceuticals, LLC. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Pain is a major health concern and a growing field of research. Molecular biologists have made rapid progress in finding relationships between genetics and pain, and Molecular Pain is the first book specifically written to bring this research to doctors and pain scientists. Unlike traditional textbooks, this book utilizes basic neuroscience to explain the mechanisms of pain. It explores current pain medicine as well as alternative treatments for chronic pain, such as acupuncture. Edited by a leading neuroscientist and written by international experts, Molecular Pain is a concise and comprehensive review of recent progress in the field of pain.
Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology. - Written by future leaders in the pain field - Covers a wide range of targets - Contains provocative ideas about the future direction of the pain field.
This book successfully explores cellular and molecular mechanisms of chronic pain based on recent basic neurobiological investigations. By focusing on major breakthroughs in basic neurosciences, it is believed to contain the promise for future new pain drug discovery.Instead of repeating extensive reviews of basic animal and clinical observations, the book provides a novel neuronal model that is believed to be the key target for treating chronic pain. In addition, it reviews and validates animal models developed for studying basic mechanisms of pain and chronic pain, and the current medicine used to treat chronic pain as well as alternative pain treatment. The final few chapters also cover how pain may interfere with other high brain functions, such as fear, anxiety, sleep, memory, etc.
This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical