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It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists. The fact that bacterial attachment to the host tissue is a prerequisite for infection understandably led to the hope that infections could be prevented by blocking the adhesion of pathogenic bacteria. Progress in this field has been so rapid that it has become difficult to keep up with recent developments. This book contains the proceedings of the symposium on the Molecular Mechanisms of Microbial Adhesion, May 6-8, 1988. Both the symposium and this book were intended as an up-to-date review of the most recent findings concerning the adhesion of medically important bacteria. In addition, this book contains critical and provocative overviews of the past, present and future of this field.
Attachment to host cells or tissues is often the first step in the establishment of bacterial infections. A complex array of recognition, attachment, and virulence factors is involved in this process, which recent research has greatly illuminated. This comprehensive and authoritative volume discusses the specific cell and tissue-specific affinities of pathogenic microorganisms, including bioinorganic surfaces such as teeth, and is an essential reference for researchers and students of host-pathogen interactions.
It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists. The fact that bacterial attachment to the host tissue is a prerequisite for infection understandably led to the hope that infections could be prevented by blocking the adhesion of pathogenic bacteria. Progress in this field has been so rapid that it has become difficult to keep up with recent developments. This book contains the proceedings of the symposium on the Molecular Mechanisms of Microbial Adhesion, May 6-8, 1988. Both the symposium and this book were intended as an up-to-date review of the most recent findings concerning the adhesion of medically important bacteria. In addition, this book contains critical and provocative overviews of the past, present and future of this field.
Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control
Introductory textbook describing the ways in which bacteria cause disease at the molecular and cellular level.
Azospirillum is a plant growth promoting rhizobacterium used for inoculation of cereal and forage crops. The book covers its physiology, ecology, biochemistry, and molecular biology. The most advanced molecular techniques to understand the regulatory mechanisms of nitrogen fixation and ammonia assimilation, as well as the basis of phytohormone production, are included. In particular, the identification of novel types of promoters, specific regulatory circuits, and new regulatory proteins is described. New insights in the plant growth promoting role of the bacteria through the analysis of their interactions with the plant are presented. Also discussed are field applications, allowing the evaluation of the physiological and agronomic involvement of Azospirillum inoculations.
An emerging theme in molecular and cellular microbiology has been the ability of many pathogens to usurp the host cell and eventually colonize the host. This interaction between bacteria and host is not unidirectional - both pathogens and host cells engage in a signalling cross-talk. Research focused on this cross-talk and discussed in this volume, reveals not only novel aspects of bacterial pathogenesis, but also key information about epithelial biology with broader implications in the prevention and treatment of infectious diseases. Written by leading researchers in this field, this book provides a valuable overview of the host-bacterial interactions that occur at mucosal surfaces including the gastrointestinal, respiratory, and urogenital tracts. It will therefore be a valuable resource for graduate students and researchers working on these systems or in the fields of molecular and cellular microbiology or infectious disease medicine.
An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.