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This volume provides a comprehensive account of the most recent trends in human leukemia, as presented at the Ninth Wilsede Meeting. The internationally renowned contributors deal with all different aspects of these diseases: As well as discussing important clinical aspects of leukemia, new information on the biological basis of leukemia gained using the methods of molecular genetics, cell and molecular biology, virology, and immunology is covered. The book shows both the complexity of leukemia research, as well as the value of basic scientific research in furthering clinical medicine and therapy.
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 17-20, 1984 Wilsede Joint Meeting on Pediatric Oncology III. Hamburg, June 21/22, 1984.
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie, Wilsede, June 21-23, 1982
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie, Hamburg, June 27/28, 1986
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 21-23, 1982
"Es ist ja ganz eineriei, wer es gejunden hat, die Hauptsache ist, daB es gejunden worden ist." This was said by Hermann Wilbrand, director of the department of opthalmology at the university hospital Hamburg-Eppendorf (1919-1923), when others claimed priority for the long searched for cortical visuell center, which he had discovered. Five years ago we tried in Wilsede an unusual experiment, bringing together for three long days and nights scientists and medical doctors to learn like students about each others work. The hope was that the participants in the workshop would discuss the whole problem of human leukemia, and coopera tive programmes among the different specialized research groups and medical centers would be stimulated. Now five years later we feel that the experiment was a success. Coope rative research programmes around the world were started and most of us understand more and more the Frederic Stohl man question about the pratical application of our research and its benefit for the patient. The chairman have done a tremendous job organizing an up to date scientific programme for the third Wilsede meet ing. I would like to thank all of them for a programme which includes all the important results and future aspects of human leukemia.
You see things, and sa)' why? But I dream 1hings that never were, and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time, June 1st, 1909, Alexander Maximov communicated in a lecture, given in the Charite in Berlin, the fundamental knowledge, that there exists a lymphoid hemopoetic stem cell. Alexander Friedenstein explained that during the following years, Maximov also showed that the idea of interaction between hemopoetic cells and their stroma to be one of the most significant experiences. Monoclonal antibodies, recombinant DNA technics and the improvement of tissue culture models are the major developments to improve our possibilities to clarify growth and differentiation functions of hemopoetic cells. During the last two decades it was shown that soluble products, released from T cells, were not only involved in inducing B cells to produce specific immunoglobulin secretion after antigen stimulation. Furthermore, lymphokines together with other cytokines regulate the growth and differentiation of hemopoetic cells. As I have learned from Dick Gershon, our knowledge of the cellular basis for immunoregulation has come a long way since 450 B.C. Thucydides comments on the possible role of immune response in controlling the Black Death. Dick Gershon speculated that no scientific interest for these interesting observations was put forth at that time. Perhaps the problems, the Athenians were having with the Spartans, converted money from basis research into the military budget.
Mene Stil in jeglicher Kunst, daft er die spezijischen Schranken derselben zu entfernen weip, ohne doch ihre spezijischen Vorzuge mit aufzuhe ben, und durch eine weise Benut zung ihrer Eigentumlichkeit ihr einen mehr allgemeinen Charakter erteilt. Friedrich Schiller - Ober die as the tische Erziehung des Menschen. In den Horen, 22. Brief (1795) We are glad that you have all come to this small village and I hope that you will feel at home here for the next few days. The special atmosphere of the surround ings will probably have a good influence on our discussions, and you will perhaps remember this when you are back home again. It takes hard work to save this little piece of nature for man in our highly industrialized world, and we should all be grateful to the Verein Naturschutzpark e. V. (founded in 1909), Alfred Toepfer and his associates for their efforts. We intend to discuss modern trends in human leukemia in this workshop, but we should also take the opportunity to reflect on the trends of the past, which might still be modern.
Fractal geometry has become popular in the last 15 years, its applications can be found in technology, science, or even arts. Fractal methods and formalism are seen today as a general, abstract, but nevertheless practical instrument for the description of nature in a wide sense. But it was Computer Graphics which made possible the increasing popularity of fractals several years ago, and long after their mathematical formulation. The two disciplines are tightly linked. The book contains the scientificcontributions presented in an international workshop in the "Computer Graphics Center" in Darmstadt, Germany. The target of the workshop was to present the wide spectrum of interrelationships and interactions between Fractal Geometry and Computer Graphics. The topics vary from fundamentals and new theoretical results to various applications and systems development. All contributions are original, unpublished papers.The presentations have been discussed in two working groups; the discussion results, together with actual trends and topics of future research, are reported in the last section. The topics of the book are divides into four sections: Fundamentals, Computer Graphics and Optical Simulation, Simulation of Natural Phenomena, Image Processing and Image Analysis.
First multi-year cumulation covers six years: 1965-70.