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This proceedings volume contains results presented at the Sixth International Workshop on Data Analysis in Astronomy — “Modeling and Simulation in Science” held on April 15-22, 2007, at the Ettore Majorana Foundation and Center for Scientific Culture, Erice, Italy. Recent progress and new trends in the field of simulation and modeling in three branches of science — astrophysics, biology, and climatology — are described in papers presented by outstanding scientists. The impact of new technologies on the design of novel data analysis systems and the interrelation among different fields are foremost in scientists' minds in the modern era. This book therefore focuses primarily on data analysis methodologies and techniques.
This proceedings volume contains results presented at the Sixth International Workshop on Data Analysis in Astronomy ? ?Modeling and Simulation in Science? held on April 15-22, 2007, at the Ettore Majorana Foundation and Center for Scientific Culture, Erice, Italy. Recent progress and new trends in the field of simulation and modeling in three branches of science ? astrophysics, biology, and climatology ? are described in papers presented by outstanding scientists. The impact of new technologies on the design of novel data analysis systems and the interrelation among different fields are foremost in scientists' minds in the modern era. This book therefore focuses primarily on data analysis methodologies and techniques.
The concept is fundamental in statistics and tailors to the emergence of collective behaviours. Communication then asks for uncertainty considerations - noise, indeterminacy or approximation - and its wider impact on the couple perception-action. Clustering being all about uncertainty handling, data set representation appears not to be the only solution: Introducing hierarchies with adapted metrics, a priori pre-improving the data resolution are other methods in need of evaluation. The technology together with increasing semantics enables to involve synthetic data as simulation results for the multiplication of sources. Part B plays with another couple important for complex systems: state vs. transition. State-first descriptions would characterize physics, while transition-first would fit biology. That could stem from life producing dynamical systems in essence.
This proceedings volume contains results presented at the Sixth International Workshop on Data Analysis in Astronomy OCo OC Modeling and Simulation in ScienceOCO held on April 15-22, 2007, at the Ettore Majorana Foundation and Center for Scientific Culture, Erice, Italy. Recent progress and new trends in the field of simulation and modeling in three branches of science OCo astrophysics, biology, and climatology OCo are described in papers presented by outstanding scientists. The impact of new technologies on the design of novel data analysis systems and the interrelation among different fields are foremost in scientists'' minds in the modern era. This book therefore focuses primarily on data analysis methodologies and techniques. Sample Chapter(s). Chapter 1: Simulations for Uhe Cosmic Ray Experiments (562 KB). Contents: Astrophysics, Cosmology and Earth Physics: Simulations for UHE Cosmic Ray Experiments (J Knapp); Problems and Solutions in Climate Modeling (A Sutera); Statistical Analysis of Quasar Data and Validity of the Hubble Law (S Roy et al.); Quantum Astronomy and Information (C Barbieri); Biology, Biochemistry and Bioinformatics: From Genomes to Protein Models and Back (A Tramontano et al.); Exploring Biomolecular Recognition by Modeling and Simulation (R Wade); BioInfogrid: Bioinformatics Simulation and Modeling Based on Grid (L Milanesi); Methods and Techniques: Optimization Strategies for Modeling and Simulation (J Louchet); Biclustering Bioinformatics Data Sets: A Possibilistic Approach (F Masulli); From the Qubit to the Quantum Search Algorithms (G Cariolaro & T Occhipinti); Comparison of Stereo Vision Techniques for Cloud-Top Height Retrieval (A Anzalone et al.); and other papers. Readership: Physicists; biologists; computer scientists and data analysts."
The book gathers articles that were exposed during the seventh edition of the Workshop ?Data Analysis in Astronomy?. It illustrates a current trend to search for common expressions or models transcending usual disciplines, possibly associated with some lack in the Mathematics required to model complex systems. In that, data analysis would be at the epicentre and a key facilitator of some current integrative phase of Science.It is all devoted to the question of ?representation in Science?, whence its name, IMAGe IN AcTION, and main thrusts Part A: Information: data organization and communication, Part B: System: structure and behaviour, Part C: Data ? System representation. Such a classification makes concepts as ?complexity? or ?dynamics? appear like transverse notions: a measure among others or a dimensional feature among others.Part A broadly discusses a dialogue between experiments and information, be information extracted-from or brought-to experiments. The concept is fundamental in statistics and tailors to the emergence of collective behaviours. Communication then asks for uncertainty considerations ? noise, indeterminacy or approximation ? and its wider impact on the couple perception-action. Clustering being all about uncertainty handling, data set representation appears not to be the only solution: Introducing hierarchies with adapted metrics, a priori pre-improving the data resolution are other methods in need of evaluation. The technology together with increasing semantics enables to involve synthetic data as simulation results for the multiplication of sources.Part B plays with another couple important for complex systems: state vs. transition. State-first descriptions would characterize physics, while transition-first would fit biology. That could stem from life producing dynamical systems in essence. Uncertainty joining causality here, geometry can bring answers: stable patterns in the state space involve constraints from some dynamics consistency. Stable patterns of activity characterize biological systems too. In the living world, the complexity ? i.e. a global measure on both states and transitions ? increases with consciousness: this might be a principle of evolution. Beside geometry or measures, operators and topology have supporters for reporting on dynamical systems. Eventually targeting universality, the category theory of topological thermodynamics is proposed as a foundation of dynamical system understanding.Part C details examples of actual data-system relations in regards to explicit applications and experiments. It shows how pure computer display and animation techniques link models and representations to ?reality? in some ?concrete? virtual, manner. Such techniques are inspired from artificial life, with no connection to physical, biological or physiological phenomena! The Virtual Observatory is the second illustration of the evidence that simulation helps Science not only in giving access to more flexible parameter variability, but also due to the associated data and method storing-capabilities. It fosters interoperability, statistics on bulky corpuses, efficient data mining possibly through the web etc. in short a reuse of resources in general, including novel ideas and competencies. Other examples deal more classically with inverse modelling and reconstruction, involving Bayesian techniques or chaos but also fractal and symmetry.
Data analysis is changing fast. Driven by a vast range of application domains and affordable tools, machine learning has become mainstream. Unsupervised data analysis, including cluster analysis, factor analysis, and low dimensionality mapping methods continually being updated, have reached new heights of achievement in the incredibly rich data wor
Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes. - Focuses on the discovery of epi-drugs as candidates to be used in therapy including combined therapies - Describes new computational methodologies and screening assays utilizing recent and emerging novel structural data - Highlights the discovery, development and optimization of epi-probes, which are molecular probes that elucidate epigenetic mechanisms - Includes important topics such as computational-guided optimization of epi-hits, virtual screening to identify novel compounds for epigenetic targets, development and mining of epigenetic molecular databases, SAR modeling of screening data and much more
Now approaching its tenth year, this hugely successful book presents an unusual attempt to publicise the field of Complex Dynamics. The text was originally conceived as a supplemented catalogue to the exhibition "Frontiers of Chaos", seen in Europe and the United States, and describes the context and meaning of these fascinating images. A total of 184 illustrations - including 88 full-colour pictures of Julia sets - are suggestive of a coffee-table book. However, the invited contributions which round off the book lend the text the required formality. Benoit Mandelbrot gives a very personal account, in his idiosyncratic self-centred style, of his discovery of the fractals named after him and Adrien Douady explains the solved and unsolved problems relating to this amusingly complex set.
Of working group C. Introduction and summary of working group C: part I / J.S.T. Ng -- Contributed papers. Is there emmitted radiation in the Unruh effect? / B.L. Hu and A. Raval -- Fermilab A0 channeling program / R.A. Carrigan, Jr. [and others] -- Integral characteristics of bremsstrahlung and pair photoproduction in a medium / V.N. Baier and V.M. Katkov -- The Coulomb corrections to e+e- pair production in ultrarelativistic heavy-ion collisions / R.N. Lee -- Spin depolarization due to beam-beam interaction in linear colliders / K.A. Thompson -- Gravitational Čerenkov radiation and scalar stars / S. Capozziello, G. Lambiase and D.F. Torres -- D. Quantum methodologies in beam physics. Plenary papers. Supersymmetry and beam dynamics / J.D. Bjorken and P. Chen -- Landau damping in nonlinear Schrödinger equations / R. Fedele [and others] -- Summary of working group D. Quantum methodology in beam physics / A. Dragt and M. Pusterla -- Contributed papers. Controlled stochastic collective dynamics of particle beams in the stability regime / C. Petroni [and others] -- Quantum mechanical formalism of particle beam optics / S.A. Khan -- Localized coherent structures and patterns formation in collective models of beam motion / A. Fedorova and M. Zeitlin -- Quasiclassical calculations for Wigner functions via multiresolution / A. Fedorova and M. Zeitlin -- Single-particle quantum dynamics in a magnetic lattice / M. Venturini and R.D. Ruth -- Quantum-like approach to beam dynamics - application to the LHC and HIDIF projects / M. Pusterla -- Quantum mechanics of Dirac particle beam optics: single-particle theory / R. Jaganathan -- Quantum models in beam physics and signal analysis / M. Manko -- Radiative corrections in symmetrized classical electrodynamics / J.R. Van Meter [and others] -- Beyond Unruh effect: nonequilibrium quantum dynamics of moving charges / B.L. Hu and P.R. Johnson.
Powerful techniques have been developed in recent years for the analysis of digital data, especially the manipulation of images. This book provides an in-depth introduction to a range of these innovative, avante-garde data-processing techniques. It develops the reader's understanding of each technique and then shows with practical examples how they can be applied to improve the skills of graduate students and researchers in astronomy, electrical engineering, physics, geophysics and medical imaging. What sets this book apart from others on the subject is the complementary blend of theory and practical application. Throughout, it is copiously illustrated with real-world examples from astronomy, electrical engineering, remote sensing and medicine. It also shows how many, more traditional, methods can be enhanced by incorporating the new wavelet and multiscale methods into the processing. For graduate students and researchers already experienced in image processing and data analysis, this book provides an indispensable guide to a wide range of exciting and original data-analysis techniques.