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One of the few modern first-person accounts of Native American healers tells us about Indian life in this world and about life in the visionary medicine womans world. A compelling history.
Contrary to the fictional account of James Fenimore Cooper, the Mohegan/Mohican nation did not vanish with the death of Chief Uncas more than three hundred years ago. In the remarkable life story of one of its most beloved matriarchsÑ100-year-old medicine woman Gladys TantaquidgeonÑMedicine Trail tells of the Mohegans' survival into this century. Blending autobiography and history, with traditional knowledge and ways of life, Medicine Trail presents a collage of events in Tantaquidgeon's life. We see her childhood spent learning Mohegan ceremonies and healing methods at the hands of her tribal grandmothers, and her Ivy League education and career in the white male-dominated field of anthropology. We also witness her travels to other Indian communities, acting as both an ambassador of her own tribe and an employee of the federal government's Bureau of Indian Affairs. Finally we see Tantaquidgeon's return to her beloved Mohegan Hill, where she cofounded America's oldest Indian-run museum, carrying on her life's commitment to good medicine and the cultural continuance and renewal of all Indian nations. Written in the Mohegan oral tradition, this book offers a unique insider's understanding of Mohegan and other Native American cultures while discussing the major policies and trends that have affected people throughout Indian Country in the twentieth century. A significant departure from traditional anthropological "as told to" American Indian autobiography, Medicine Trail represents a major contribution to anthropology, history, theology, women's studies, and Native American studies.
Literally Italian for "bad air," malaria once plagued Rome, tropical trade routes and colonial ventures into India and South America and the disease has no known antidote aside from the therapeutic effects of the "miraculous" quinine. This first book from journalist Honigsbaum is a rousing history of the search for febrifuge or, more specifically, the rare red cinchona tree, the bark from which quinine is derived.
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Successful drug development relies on accurate and efficient clinical trials to deliver the best and most effective pharmaceuticals and clinical care to patients. However, the current model for clinical trials is outdated, inefficient and costly. Clinical trials are limited by small sample sizes that do not reflect variations among patients in the real world, financial burdens on participants, and slow processes, and these factors contribute to the disconnect between clinical research and clinical practice. On November 28-29, the National Academies of Sciences, Engineering, and Medicine convened a workshop to investigate the current clinical trials system and explore the potential benefits and challenges of implementing virtual clinical trials as an enhanced alternative for the future. This publication summarizes the presentations and discussions from the workshop.
Written by local author Jean Arthur, Top Trails: Glacier National Park leads visitors to secluded trails and unique settings while providing details of current and past human activity, wildlife movement, and geologic changes that altered the landscape and created America’s tenth national park. The unique approach of Top Trails: Glacier National Park reveals the best trails that wind alongside sensitive meadows and climb above crystalline lakes and leads hikers to backcountry respites unique to Glacier. The guide also traces outlaws, poachers, and mining ventures that occurred inside the current park boundary.
Dengue fever is the world’s most prevalent mosquito-borne illness, but Alex Nading argues that people in dengue-endemic communities do not always view humans and mosquitoes as mortal enemies. Drawing on two years of ethnographic research in urban Nicaragua and challenging current global health approaches to animal-borne illness, Mosquito Trails tells the story of a group of community health workers who struggle to come to terms with dengue epidemics amid poverty, political change, and economic upheaval. Blending theory from medical anthropology, political ecology, and science and technology studies, Nading develops the concept of “the politics of entanglement” to describe how Nicaraguans strive to remain alive to the world around them despite global health strategies that seek to insulate them from their environments. This innovative ethnography illustrates the continued significance of local environmental histories, politics, and household dynamics to the making and unmaking of a global pandemic.
Explore trails and points of interest in the Medicine Bow National Forest.