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Critical Appraisal of Medical Literature provides a step-by-step approach to help the reader reach a good level of proficiency in systematic critical appraisal of medical information. To this end, the book covers all the elements that are necessary to develop these skills and is a comprehensive guide to the subject. The book is written in three parts. The first part focuses on the logical justification and the validity of medical information. Its chapters present basic working definitions and discussions on relevant basic topics of statistics and epidemiology. The second part focuses on the complementary aspects of critique, common study designs and articles whose main topics are treatment, diagnosis, prognosis, aetiology, reviews, medical guidelines, audit, and qualitative research. The third part presents some statistical techniques that are commonly used in published articles. Critical Appraisal of Medical Literature is intended for those interested in developing critical appraisal skills such as psychiatric trainees preparing for the Critical Review Paper of the MRCPsych Examination in the UK, other practitioners as part of their preparation for examinations, and medical professionals and students as part of their introduction to aspects of systematic critical appraisal of medical information.
READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basics to more advanced techniques. Illustrated throughout by detailed case studies and worked examples Includes exercises in all chapters Accessible to anyone with a basic knowledge of statistics Authors are at the forefront of research into Bayesian methods in medical research Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.
Holistic approach to understanding medical statistics This hands-on guide is much more than a basic medical statistics introduction. It equips you with the statistical tools required for evidence-based clinical research. Each chapter provides a clear step-by-step guide to each statistical test with practical instructions on how to generate and interpret the numbers, and present the results as scientific tables or graphs. Showing you how to: analyse data with the help of data set examples (Click here to download datasets) select the correct statistics and report results for publication or presentation understand and critically appraise results reported in the literature Each statistical test is linked to the research question and the type of study design used. There are also checklists for critically appraising the literature and web links to useful internet sites. Clear and concise explanations, combined with plenty of examples and tabulated explanations are based on the authors’ popular medical statistics courses. Critical appraisal guidelines at the end of each chapter help the reader evaluate the statistical data in their particular contexts.
This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
CD-ROM contains: Coverage of research and design methods -- Statistical software and data sets.
Approximately 4 million U.S. service members took part in the wars in Afghanistan and Iraq. Shortly after troops started returning from their deployments, some active-duty service members and veterans began experiencing mental health problems. Given the stressors associated with war, it is not surprising that some service members developed such mental health conditions as posttraumatic stress disorder, depression, and substance use disorder. Subsequent epidemiologic studies conducted on military and veteran populations that served in the operations in Afghanistan and Iraq provided scientific evidence that those who fought were in fact being diagnosed with mental illnesses and experiencing mental healthâ€"related outcomesâ€"in particular, suicideâ€"at a higher rate than the general population. This report provides a comprehensive assessment of the quality, capacity, and access to mental health care services for veterans who served in the Armed Forces in Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn. It includes an analysis of not only the quality and capacity of mental health care services within the Department of Veterans Affairs, but also barriers faced by patients in utilizing those services.
First Edition Received 100 Points and 5-Star Doody'sReview! This is the only nursing text to facilitate the achievement by Doctor of Nursing Practice graduates (DNPs) s of the highest possible competency in conducting systematic and in-depth evaluations of all aspects of health care. The second edition of this award-winning text keeps pace with the rapidly evolving health care market by presenting a more comprehensive range of evaluation strategies for analyzing quality, safety, and value in health care practice and programs, with an emphasis on conducting, interpreting, and disseminating findings. It includes three new chapters addressing evaluation and outcomes, program evaluation, quality improvement, and reporting and disseminating the results. Based on the best evidence-based practices, the book provides DNPs with in-depth information on the conceptual basis of evaluation, its application as an integral part of contemporary health care delivery, and resources and methodology for evaluation of practice outcomes. It includes a critical examination of the characteristics, sources, and quality of the nature of evidence and presents several different evaluation models including those that focus oneconomic evaluation. The evaluation of organizations, systems, and standards for practice are covered in detail as are the evaluation of populations and health care teams, particularly interdisciplinary collaborative health teams. Also addressed is the process for translating outcomes from evaluation into health care policy, and opportunities for advocacy and leadership. Numerous examples and case studies illustrate concepts. New to the Second Edition: Includes three (3) new chapters that address evaluation and outcomes, program evaluation, quality improvement, and reporting and disseminating the results Explores health care practice determinates related to quality, safety, and value Covers how to lead and participate in comprehensive health care evaluations using best practices in conduct, interpretation and dissemination Includes strategies for evaluating small, medium, and large programs Key Features: Facilitates competency in conducting systematic and in-depth evaluations of all aspects of health care Based on best practices and evidence based practices Offers practical methods and tools used to conduct and implement a QI project Provides numerous examples and case studies Encourages the dissemination of results using a variety of venues, such as formal presentations, posters, and publications